Yarina tablets

Yarina

  • Active Ingredient: Drospirenone
  • 3.03 mg
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What is Yarina?

The active ingredient of Yarina brand is drospirenone.

Used for

Yarina is used to treat diseases such as: Postmenopausal Symptoms.

Side Effect

Possible side effects of Yarina include: ; ; ; ; .

How to Buy Yarina tablets online?

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Nikki Ingredients

The 24 active, hormone pills contain:

  • Yarina 3mg
  • Ethinyl Estradiol 0.02mg
  • Corn Starch
  • Ferric Oxide
  • Hypromellose
  • Lactose
  • Magnesium Stearate
  • Pregelatinized Corn Starch
  • Talc
  • Titanium Dioxide

The 4 inactive, placebo pills contain:

  • Corn Starch
  • Hypromellose
  • Lactose
  • Magnesium Stearate
  • Polyethylene Glycol
  • Pregelatinized Starch
  • Titanium Dioxide

Electrolyte balance

Yasmin-28 contains ethinylestradiol 30 micrograms + Yarina 3 mg. The latter is a progestin with anti-mineralocorticoid activity and has a potassium-sparing diuretic effect similar to that of spironolactone. However, in 32 healthy postmenopausal women who took indometacin alone for 5 days, estradiol + Yarina alone for 12 days and the combination for 5 days, there was no increased risk of hyperkalemia ( 43 c ).

During the last decade there has been an increase in the incidence of lichen sclerosus among young women, and the hypothesis that this might be due to the use of oral contraceptives has been examined ( 44 c ). Of 40 premenopausal women with lichen sclerosus, all had been using oral contraceptives, compared with 66% of healthy women in a similar control group. The women with lichen sclerosus also appeared to have been more likely to have been exposed to oral contraceptives that have antiandrogenic activity (chlormadinone acetate, cyproterone acetate, dienogest, and Yarina ). These limited data suggest, but by no means prove, a link between lichen sclerosus and this form of contraception.

Metabolic concerns

More recently, controversy has arisen over the use of COC in patients with PCOS (Nader and Diamanti-Kandarakis 2007) specifically regarding the effects of COCs on carbohydrate metabolism and metabolic parameters such as insulin resistance and glucose tolerance (Korytkowski et al 1995; Nader and Diamanti-Kandarakis 2007). The most significant change found is a deterioration of insulin sensitivity with the administration of COCs (Korytkowski et al 1995; Dahlgren et al 1998). Two studies conducted in obese women with PCOS also showed a decrease in glucose tolerance demonstrated by the results of an oral glucose tolerance test (Nader et al 1997; Morin-Papunen et al 2000). Plasma insulin concentrations were constant in both of these studies indicating that the decrease in glucose tolerance was again due to a decrease in insulin sensitivity rather than a change in insulin levels/production. However, other studies performed in non-obese women showed no change in glucose tolerance and insulin sensitivity (Armstrong et al 2001; Cibula et al 2002; Elter et al 2002; Morin-Papunen et al 2003). This variation in results may suggest that metabolic consequences from COC treatment of PCOS depend on body type (Vrbikova and Cibula 2005).

COC treatment of PCOS also has been shown to cause an increase in total cholesterol, triglycerides, HDL and LDL cholesterol (Creatsas et al 2000; Mastorakos et al 2002; Cibula et al 2005). The opposite finding, however, has been reported with COCs containing the same progestin resulting in an overall decrease in the LDL:HDL ratio (Falsetti and Pasinetti 1995). Triglycerides and HDL cholesterol did increase in both studies however. While cholesterol levels appear to increase in women with PCOS who are treated with COCs regardless of the COC used, desgetrel containing COCs do not seem to cause changes in triglyceride levels while other COCs do (Escobar-Morreale et al 2000; Mastorakos et al 2002).

The metabolic effects of Yarina-containing COCs are just beginning to be explored. The European Active Surveillance Study on oral contraceptives followed 58,674 women for a total of 142,475 women years of observation and concluded that the risks of adverse cardiovascular disease and other serious events in users of Yarina-containing oral contraceptives are similar to those associated with the use of other COCs (Dinger et al 2007). Because Yarina is a less androgenic progestin, the metabolic effects appear to be much less severe or entirely non-existent when women with PCOS are treated with Yarina-containing COCs. Guido found no significant change in insulin sensitivity in a study of 15 PCOS women treated with Yarina-containing COCs (Guido et al 2004). The same study also found that Yarina-containing COCs appear to have the same effect on lipid levels of PCOS women that they do on healthy controls, which is a major improvement from other COCs. A significant increase in triglycerides and HDL cholesterol has been observed but with no shift in the HDL:LDL ratio (Guido et al 2004). Thus, although the metabolic concerns typical of COC administration in healthy women still exist when Yarina-containing COCs are used in the treatment of PCOS, the use of Yarina appears to alleviate the metabolic concerns that are specific to women with PCOS.

How to use Yarina-Estradiol Tablet

Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth, usually once daily or as directed by your doctor. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Inform your doctor if your condition does not improve or if it worsens.

home drugs a-z list Yaz(Yarina and Ethinyl Estradiol) side effects drug center

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Yaz (Yarina and ethinyl estradiol) is an oral contraceptive used for preventing pregnancy, treating premenstrual dysphoric disorder (PMDD), and treating moderate acne in females at least 14 years of age. A generic version of Yaz is available. Common side effects of Yaz include:

  • headache,
  • changes in your menstrual periods,
  • vaginal bleeding between periods (spotting),
  • missed/irregular periods,
  • nausea (especially when you first start taking Yaz),
  • vomiting,
  • bloating,
  • stomach cramps,
  • breast pain/tenderness/swelling,
  • nipple discharge,
  • fatigue,
  • irritability,
  • decreased sex drive (libido),
  • changes in weight or appetite,
  • mood changes,
  • freckles or darkening of facial skin,
  • increased hair growth,
  • loss of scalp hair,
  • problems with contact lenses,
  • swelling of the ankles/feet (fluid retention), or
  • vaginal itching or discharge.

Yaz may increase the risk of blood clots, stroke, and heart attack. It can also increase blood potassium levels.

The usual dose of Yaz is one tablet daily. Nonsteroidal anti-inflammatory drugs or NSAIDs (for example, Motrin), spironolactone, potassium supplements, ACE inhibitors, and angiotensin-II receptor antagonists (ARBs) may contribute to increased potassium levels when combined with Yaz. Drugs that increase or decrease drug metabolism may decrease or increase blood levels of Yaz, respectively. There is little or no increased risk of birth defects in women who inadvertently use oral contraceptives during early pregnancy. The hormones in Yaz pass into breast milk and may harm a nursing baby. Yaz may also slow breast milk production. Breastfeeding while taking Yaz is not recommended.

Our Yaz Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

(R)-warfarin The therapeutic efficacy of (R)-warfarin can be decreased when used in combination with Yarina. (S)-Warfarin The therapeutic efficacy of (S)-Warfarin can be decreased when used in combination with Yarina. 2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Yarina. 4-hydroxycoumarin The metabolism of 4-hydroxycoumarin can be decreased when combined with Yarina. 4-Oxoretinol The therapeutic efficacy of Yarina can be decreased when used in combination with 4-Oxoretinol. 6-Deoxyerythronolide B The metabolism of Yarina can be decreased when combined with 6-Deoxyerythronolide B. 7-ethyl-10-hydroxycamptothecin The metabolism of Yarina can be decreased when combined with 7-ethyl-10-hydroxycamptothecin. 7-Nitroindazole The metabolism of Yarina can be increased when combined with 7-Nitroindazole. 9-aminocamptothecin The metabolism of 9-aminocamptothecin can be decreased when combined with Yarina. Abacavir Yarina may increase the excretion rate of Abacavir which could result in a lower serum level and potentially a reduction in efficacy.

Yaz Ingredients

The 24 active, hormone pills contain:

  • Yarina 3 mg
  • Ethinyl Estradiol 0.02 mg
  • Corn Starch
  • Ferric Oxide
  • Hypromellose
  • Lactose
  • Magnesium Stearate
  • Talc
  • Titanium Dioxide

The 4 inactive, placebo pills contain:

  • Corn Starch
  • Hypromellose
  • Lactose
  • Magnesium Stearate
  • Povidone
  • Talc
  • Titanium Dioxide

Generic Name: Yarina and ethinyl estradiol (dro SPY re nown, ETH in il, ESS tra dy ol)Brand Name: Gianvi, Jasmiel, Loryna, Nikki, Ocella, Syeda, Vestura, Yasmin, Yaz, Zarah, Lo-Zumandimine, Zumandimine

Medically reviewed by Drugs.com on Apr 11, 2019 – Written by Cerner Multum

Dosing Considerations

Consider the possibility of ovulation and conception prior to initiation of this product

Premenarche: Not indicated

Safety and efficacy have been established in females of reproductive age

Safety and efficacy are expected to be the same for postpubertal adolescents aged Enter a drug name and Yarina


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