Mirena tablets


  • Active Ingredient: Levonorgestrel
  • 0.15 mg
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What is Mirena?

The active ingredient of Mirena brand is levonorgestrel. The originating document has been archived. We cannot confirm the completeness, accuracy and currency of the content.

Used for

Mirena is used to treat diseases such as: Abnormal Uterine Bleeding, Birth Control, Emergency Contraception.

Side Effect

Possible side effects of Mirena include: intradermal implant, intradermal kit; irregular menstruation; headache; Heavy or light menstrual bleeding; pain.

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What is the dosage for oral Mirena?

  • Emergency contraception pills should be taken as soon as possible and not more than 72 hours after unprotected sex or when birth control fails.
  • Single dose regimen: Take one 1.5 mg tablet as soon as possible within 72 hours of unprotected sex or when birth control fails.
  • Two-dose regimen: Take one 0.75 mg tablet as soon as possible within 72 hours of unprotected sex or when birth control fails, followed by a second 0.75 mg tablet 12 hours later.

Do I need a prescription for Mirena-oral?

No. Most emergency contraception pills can be purchased over-the-counter or OTC (without a prescription). However, some age restrictions may apply.

How should this medicine be used?

Mirena comes as a tablet to take by mouth. If you are taking Mirena as a single tablet product , take one tablet as soon as possible within 72 hours after unprotected sexual intercourse. If you are taking Mirena as a two tablet product, take one tablet as soon as possible within 72 hours after unprotected sexual intercourse and take a second dose 12 hours later. Mirena works best if it is taken as soon as possible after unprotected sexual intercourse. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Mirena exactly as directed.

If you vomit less than 2 hours after you take a dose of Mirena, call your doctor. You may need to take another dose of this medication.

Because you can become pregnant soon after treatment with Mirena, you should continue using your regular method of birth control or begin using regular birth control immediately.

What other drugs will affect Mirena emergency contraceptive?

Certain other medications can make Mirena emergency contraceptive less effective, which may result in pregnancy. Ask a doctor or pharmacist if Mirena emergency contraceptive is safe to use if you are using any of the following medications:

This list is not complete. Other drugs may affect Mirena, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Uses of Mirena:

  • It is used to lower the chance of pregnancy after unprotected sex.

Mirena Precautions

  • Mirena does not protect against HIV infection (AIDS) and other sexually transmitted diseases (STDs).
  • Cigarette smoking increases the risk of serious cardiovascular (CV) events. Risk increases with age (>35 yrs) and with the number of cigarettes smoked.
  • Should not be used by women who are >35 yrs of age and smoke.

Do not use this medication if you:

  • might be pregnant
  • have had a serious pelvic infection called pelvic inflammatory disease (PID) unless you have had a normal pregnancy after the infection went away
  • have an untreated pelvic infection now
  • have had a serious pelvic infection in the past 3 months after a pregnancy
  • more than one sexual partner or your partner has more than one partner
  • problems with your immune system
  • intravenous drug abuse
  • have or suspect you might have cancer of the uterus or cervix
  • have bleeding from the vagina that has not been explained
  • have liver disease or liver tumor
  • have breast cancer now or in the past or suspect you have breast cancer
  • have an intrauterine device in your uterus already
  • have a condition of the uterus that changes the shape of the uterine cavity, such as large fibroid tumors
  • are allergic to Mirena, silicone, or polyethylene
  • Uses of Mirena

    Mirena is a prescription medication that is a hormone-releasing system placed in the uterus to prevent pregnancy for up to 5 years. It is also used to lessen menstrual blood loss in women who have heavy menstrual flow and who also want to use a birth control method that is placed in the uterus to prevent pregnancy.

    This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

    Mirena Interactions

    Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

    • barbiturates
    • bosentan
    • carbamazepine
    • felbamate
    • griseofulvin
    • oxcarbazepine
    • phenytoin
    • rifampin
    • St. John’s wort
    • topiramate
    • HIV protease inhibitors
    • non-nucleoside reverse transcriptase inhibitors

    This is not a complete list of Mirena drug interactions. Ask your doctor or pharmacist for more information.

    Mirena Usage

    First, your healthcare provider will examine your pelvis to find the exact position of your uterus. Your healthcare provider will then clean your vagina and cervix with an antiseptic solution, and slide a thin plastic tube containing the intrauterine device (IUD) into your uterus. Your healthcare provider will then remove the plastic tube, and leave the IUD in your uterus. Your healthcare provider will cut the threads to the right length. Placement takes only a few minutes during an office visit.

    You may experience pain, bleeding or dizziness during and after placement. If these symptoms do not pass 30 minutes after placement, the IUD may not have been placed correctly. Your healthcare provider will examine you to see if the IUD needs to be removed or replaced.

    You should check that the IUD is in proper position by feeling the removal threads. You should do this after each menstrual period. First, wash your hands with soap and water. Feel for the threads at the top of your vagina with your clean fingers. The threads are the only part of the IUD you should feel when it is in your uterus. Be careful not to pull on the threads. If you feel more than just the threads, the IUD is not in the right position and may not prevent pregnancy. Call your healthcare provider to have it removed. If you cannot feel the threads at all, ask your healthcare provider to check the IUD is still in the right place. In either case, use a non-hormonal birth control method (such as condoms or spermicide) until otherwise advised by your healthcare provider.

    Call your healthcare provider if you have any questions or concerns. Otherwise, you should return to your healthcare provider for a follow-up visit 4 to 12 weeks after the IUD is placed to make sure that it is in the right position.

    Tampons may be used with the IUD.

    Call your healthcare provider if you have any concerns about this medication. Be sure to call if you:

    • think you are pregnant
    • have pelvic pain or pain during sex
    • have unusual vaginal discharge or genital sores
    • have unexplained fever
    • might be exposed to sexually transmitted diseases (STDs)
    • cannot feel the IUD threads
    • develop very severe or migraine headaches
    • have yellowing of the skin or whites of the eyes. These may be signs of liver problems.
    • have a stroke or heart attack
    • or your partner becomes HIV positive
    • have severe vaginal bleeding or bleeding that lasts a long time

    Mirena may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • heavier or lighter than usual menstrual bleeding
    • spotting or bleeding between menstrual periods
    • nausea
    • vomiting
    • diarrhea
    • tiredness
    • headache
    • dizziness
    • breast pain or tenderness

    Mirena IUD

    The Mirena IUD or LNg 20‐IUD (Mirena) is a T‐shaped polyethylene device with a collar containing 52 mg of Mirena dispersed in polydimethylsiloxane attached to the vertical arm. This frame is also visible on x‐ray. The device releases 15 μg of Mirena daily in vivo.

    The LNg 20‐IUD is approved for up to 5 years in the United States, but is effective for up to 7 years. It is currently the most effective form of reversible contraception available (see Table 7‐1 ). Unlike the copper IUD, the LNg 20‐IUD actually reduces dysmenorrhea and decreases menstrual blood loss. Women receiving this type of IUD should be counseled regarding the altered bleeding patterns that can occur. Significant intramenstrual bleeding and spotting may occur during the first few months of use as the endometrial lining is thinning. Most women will experience lighter, shorter menses with continued use, with 20% of women becoming amenorrheic after 12 months of use. In fact, this decrease in menstrual bleeding has allowed the LNg‐20 IUD to be used as an alternative to hysterectomy and endometrial ablation for the treatment of menorrhagia, as well as a means of protecting the endometrium with hormone replacement therapy and as an adjuvant therapy for tamoxifen users. The LNg 20‐IUD may be a particularly useful method of contraception for women with hematologic disorders or for those who are taking chronic anticoagulants.

    Mirena Tablets

    Mirena Tablets 0.75mg is a generic form of Plan B. This product is no longer manufactured, but you may occasionally find it in stock. The package instructions state that you should take 1 white pill within 72 hours after unprotected sex and 1 more peach pill 12 hours later. Each dose contains 0.75 mg of Mirena (the two pills are identical, so it does not matter which pill you take first). However, research indicates that both doses can be taken at the same time up to 120 hours after unprotected sex. The pills are more effective the sooner they are taken, so take 2 Mirena pills at the same time as soon as possible after unprotected intercourse.

    Click here detailed labeling information from the manufacturer of Mirena Tablets.

    Why is this medication prescribed?

    Mirena is used to prevent pregnancy after unprotected sexual intercourse (sex without any method of birth control or with a birth control method that failed or was not used properly ). Mirena should not be used to prevent pregnancy on a regular basis. This medication is to be used as an emergency contraceptive or backup in case regular birth control fails or is used incorrectly. Mirena is in a class of medications called progestins. It works by preventing the release of an egg from the ovary or preventing fertilization of the egg by sperm (male reproductive cells). It also may work by changing the lining of the uterus (womb) to prevent development of a pregnancy. Mirena may prevent pregnancy, but it will not prevent the spread of human immunodeficiency virus (HIV, the virus that causes acquired immunodeficiency syndrome ) and other sexually transmitted diseases.

    COMMON BRAND(S): Amethyst, Lybrel

    GENERIC NAME(S): Mirena-Ethinyl Estrad

    Do not use this medication if you smoke cigarettes/use tobacco and are over 35 years old. Smoking raises your risk of stroke, heart attack, blood clots, and high blood pressure from hormonal birth control (such as the pill, patch, ring). The risk of these serious problems increases with age and with the number of cigarettes you smoke. Do not smoke or use tobacco.

    This combination hormone medication is used to prevent pregnancy. It contains 2 hormones: Mirena (a progestin) and ethinyl estradiol (an estrogen). It works mainly by preventing the release of an egg (ovulation) during your menstrual cycle. It also makes vaginal fluid thicker to help prevent sperm from reaching an egg (fertilization) and changes the lining of the uterus (womb) to prevent attachment of a fertilized egg.

    Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, decrease your risk of ovarian cysts, and also treat acne.

    Using this medication does not protect you or your partner against sexually transmitted diseases (such as HIV, gonorrhea, chlamydia).

    Mirena Dosage

    The intrauterine device (IUD) contains 52 mg of Mirena. Initially, Mirena is released at a rate of approximately 20 mcg/day. This rate decreases over time to half that amount after 5 years.

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    Is oral Mirena safe to take if I'm pregnant or breastfeeding?

    • Emergency contraception pills will not work if you are already pregnant and should not be used during pregnancy.
    • Mirena is thought to enter human milk after oral administration and should be used cautiously in nursing mothers.

    Intrauterine administration of Mirena

    The Mirena system for intrauterine administration of Mirena is estimated to release some 20 micrograms of the drug daily. This has been the subject of some sharply differing assessments. In a mailed questionnaire study of 1056 British women who had been treated with this product for menstrual disorders, 73% had continued using the system, having found that it provided relief; the most common adverse effect was menstrual spotting (19%) .

    The possible long-term effects of a Mirena-releasing intrauterine system on the endometrium and lipid profile have been examined in 142 postmenopausal women with breast cancer who took tamoxifen and were studied for 36 months. At the end of this period there were only very minor changes in serum lipids, fewer endometrial polyps, and no endometrial hyperplasia in the study group compared with a control group taking tamoxifen alone. The authors concluded that use of the Mirena-releasing intrauterine system may reduce the need for investigation of adverse effects in women taking tamoxifen and may also reduce patient discomfort while improving adherence to treatment .

    However, some women express a dislike for the Mirena intrauterine releasing system, declaring that they have an excessive incidence of adverse reactions. When another hospital sent questionnaires to 203 British women in whom the device had been inserted over a 5-year period it was found that the continuation rate fell progressively from 85% after the first 6 months to 50% after 4 or 5 years . The median duration of use was only 270 days. The principal reasons for requesting removal were unscheduled bleeding, progestogenic adverse effects, or abdominal pain.

    This may well prove to be one of the situations in which patient satisfaction with a method of treatment appears to differ markedly from one place to another, and especially between countries. Differences in the tradition of treatment or in the manner in which a physician presents a proposed therapy to the patient may be important factors determining patients’ expectations. The British report (published under the heading “Why do some people dislike it?”) needs to be set alongside an Austrian study of 180 000 users of the intrauterine system, many of them apparently very satisfied with the method. To cite a group of 13 Austrian authors: “Reliability, comfort, excellent compatibility and less severe, shorter and less painful monthly periods were the most frequently named advantages of the Mirena-releasing . Medication-induced cervical priming before insertion can be carried out on a routine or selective basis (for example in nullipara, in women who have undergone cervical conisation or in women who have previously experienced painful insertion). There is, at present, no evidence of an increased rate of breast cancer … A directly comparative study with oral contraceptives in young nullipara showed excellent results for the Mirena-releasing ” . A Spanish group similarly considered that the system “meets the effectiveness and tolerability criteria for being considered as a first choice treatment option for women with idiopathic menorrhagia” .

    Estradiol-Mirena S >

    Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

    Call your doctor at once if you have:

    • heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
    • signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
    • signs of a blood clot--sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs;
    • memory problems, confusion, unusual behavior;
    • unusual vaginal bleeding, pelvic pain;
    • a lump in your breast; or
    • high levels of calcium in your blood--nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, lack of energy.

    Common side effects may include:

    • nausea, vomiting, bloating, stomach cramps;
    • fluid retention (swelling, rapid weight gain);
    • headache;
    • breast pain;
    • redness or irritation where the patch was worn;
    • thinning scalp hair; or
    • vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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