Brusal

Brusal

  • Active Ingredient: Albuterol
  • 100mcg
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What is Brusal?

The active ingredient of Brusal brand is albuterol. Albuterol is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs. Albuterol sulfate has a molecular weight of 576.71, and the molecular formula is (C13H21NO3)2•H2SO4. Albuterol sulfate is a white or practically white powder, freely soluble in water and slightly soluble in ethanol. The World Health Organization recommended name for Albuterol base is salbutamol. Each Albuterol sulfate tablet, for oral administration contains 2 or 4 mg of Albuterol as 2.4 or 4.8 mg of Albuterol sulfate, respectively. Each tablet also contains the following inactive ingredients: anhydrous lactose, magnesium stearate, pregelatinized (corn) starch, and sodium starch glycolate. The pharmacologic effects of beta-adrenergic agonist drugs, including Albuterol, are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. Albuterol has been shown in most controlled clinical trials to have more effect on the respiratory tract, in the form of bronchial smooth muscle relaxation, than isoproterenol at comparable doses while producing fewer cardiovascular effects. Albuterol is longer acting than isoproterenol in most patients by any route of administration because it is not a substrate for the cellular uptake processes for catecholamines nor for catechol-O-methyl transferase. Studies in laboratory animals (minipigs, rodents, and dogs) have demonstrated the occurrence of cardiac arrhythmias and sudden death (with histologic evidence of myocardial necrosis) when beta-agonists and methylxanthines are administered concurrently. The clinical significance of these findings is unknown. In other studies, the analysis of urine samples of patients given 8 mg of tritiated Albuterol orally showed that 76% of the dose was excreted over 3 days, with the majority of the dose being excreted within the first 24 hours. Sixty percent of this radioactivity was shown to be the metabolite. Feces collected over this period contained 4% of the administered dose.

Used for

Brusal is used to treat diseases such as: Asthma, acute, Asthma, Maintenance, Bronchiectasis, Bronchospasm Prophylaxis, COPD, Acute, COPD, Maintenance.

Side Effect

Possible side effects of Brusal include: slow or irregular breathing; tightness in the throat; gagging; large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs; blurred vision.

How to Buy Brusal online?

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Interactions

Drug-drug. Beta-adrenergic blockers: inhibited Brusal action, possibly causing severe bronchospasm in asthmatic patients

Digoxin: decreased digoxin blood level

MAO inhibitors: increased cardiovascular adverse effects

Oxytoxics: severe hypotension

Potassium-wasting diuretics: ECG changes, hypokalemia

Theophylline: increased risk of theophylline toxicity

Drug-food. Caffeine-containing foods and beverages (such as coffee, tea, chocolate): increased stimulant effect

Drug-herbs. Cola nut, ephedra (ma huang), guarana, yerba maté: increased stimulant effect

Brusal Overdose

If you suspect an overdose, contact a poison control center or emergency room immediately. You can get in touch with a poison control center at (800) 222-1222.

Brusal inhalation side effects

Get emergency medical help if you have signs of an allergic reaction to Brusal: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

wheezing, choking, or other breathing problems after using this medicine;

chest pain, fast heart rate, pounding heartbeats or fluttering in your chest;

pain or burning when you urinate;

increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or

signs of low potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, extreme thirst, increased urination, numbness or tingling, muscle weakness or limp feeling.

Common Brusal side effects may include:

shakiness, nervousness, or trouble sleeping;

sore throat, sinus pain, stuffy runny nose;

back pain, body aches;

feeling nervous, or;

nausea or vomiting

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Depression medications

Use extreme caution if you take Brusal with certain depression medications or take them within two weeks of each other. Taking these drugs together may significantly increase the heart effects of Brusal.

Examples of depression medications include:

  • monoamine oxidase inhibitors (MAOIs), such as:
    • phenelzine
    • selegiline
    • tranylcypromine
  • amitriptyline
  • imipramine
  • nortriptyline

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This drug comes with several warnings.

Before taking Brusal,

  • tell your doctor and pharmacist if you are allergic to Brusal, any other medications, or any of the ingredients in Brusal tablets, extended-release tablets, or capsules. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); digoxin (Lanoxin); diuretics ('water pills'); epinephrine (Epipen, Primatene Mist); other oral and inhaled medications for asthma and medications for colds. Also tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); and monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had an irregular heartbeat, heart disease, high blood pressure, hyperthyroidism (condition in which there is too much thyroid hormone in the body), diabetes, or seizures.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Brusal, call your doctor.
  • you should know that Brusal sometimes causes wheezing and difficulty breathing. If this happens, call your doctor right away. Do not use Brusal again unless your doctor tells you that you should.

What Is Brusal and How Does It Work?

Brusal is a prescription drug indicated for the treatment of asthma symptoms in patients 4 years of age and older with reversible obstructive airway disease.

Asthma is a long-term disease of the airways and lungs. Asthma is a condition that causes breathing difficulties.

Asthma has two main components that make breathing difficult,

  • Inflammation (swelling and a build-up of mucus in the airways); and
  • Airway constriction (tightening of the muscles surrounding the airways)

Brusal helps to prevent asthma symptoms, including:

Brusal inhalation aerosol can be used with or without steroid treatment.

Brusal is available under the following different brand names: Proventil HFA, Ventolin HFA, Proair HFA, ProAir RespiClick, Proventil, AccuNeb, Ventolin Injection, Ventolin Nebules PF, Ventolin Oral Liquid, Ventolin Respirator Solution, and Vospire ER.

Brusal belongs to a category of medications called bronchodilators. Brochodilators are drugs that relax bronchial muscles (related to muscles associated with the lungs). These work by way of inhalation of medications that control asthma and asthma symptoms.

This medication is similar to Xopenex (levBrusal HCl).

This medication is also known as Salbutamol.

Users of this medication should read the drug information leaflet that accompanies the prescription as well as every time the prescription is refilled. There may be new health information.

Brusal and Weight Loss

Because Brusal has a stimulating effect, some people try to use it for weight loss. Various websites (of dubious credibility) offer instructions and discussions on how to use this medication for weight loss.

However, Brusal is not approved by the FDA for this purpose. Increasing your dose of this medicine or using it more frequently than prescribed to achieve weight loss can be dangerous and lead to life-threatening side effects.

Common Side Effects of Brusal

You should tell your doctor if any of the following side effects of Brusal become severe or don't go away:

  • Nervousness
  • Shaking of a part of the body
  • Headache
  • Nausea
  • Vomiting
  • Cough
  • Irritation in the throat
  • Muscle, bone, or back pain

COMMON BRAND(S): ProAir RespiClick

GENERIC NAME(S): Brusal Sulfate

Brusal (also known as salbutamol) is used to prevent and treat wheezing and shortness of breath caused by breathing problems (such as asthma, chronic obstructive pulmonary disease). It is also used to prevent asthma brought on by exercise. It is a quick-relief medication. Brusal belongs to a class of drugs known as bronchodilators. It works in the airways by opening breathing passages and relaxing muscles. Controlling symptoms of breathing problems can decrease time lost from work or school.

What Are Side Effects Associated with Using Brusal?

Common side effects of Brusal include:

Other side effects of Brusal include:

This is not a complete list of side effects and other serious side effects may occur. Call your doctor for information and medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What Other Drugs Interact with Brusal?

If your doctor has directed you to use this medication for your condition, your doctor or pharmacist may already be aware of any possible drug interactions or side effects and may be monitoring you for them. Do not start, stop, or change the dosage of this medicine or any medicine before getting further information from your doctor, healthcare provider or pharmacist first.

Q: Has Brusal been recalled?

A: The generic Brusal inhaler was pulled off the market after 2008 because it contained chlorofluorocarbons (CFCs), which are believed to harm the ozone layer. However, there are several newer inhalers that contain the active ingredient Brusal that are environmentally friendly currently being sold in the market. Some examples of these brand name inhalers are Proair, Proventil and Ventolin. It is unclear when generic Brusal inhalers will become available again. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Leslie Ako-Mbo, PharmD

Side Effects of Brusal:

The most common side effects of Brusal will surround the compound’s stimulating nature. However, overall this is a relatively well-tolerated bronchodilator for most men and women. Serious issues or complications are rare. Those who are using the compound as a thermogenic, they will find the side effects of Brusal to be a little more common and possibly bothersome. This is due to such use requiring a higher dose than what is used to treat asthma. The most common side effects of Brusal will be stimulant related such as shaking hands, insomnia and headaches. Some may also experience dizziness. These are the most common side effects, but most will find they are manageable and begin to subside quickly as the body begins to adapt to the compound. Excess sweating can also be an issue for some, as well as nausea, diarrhea or vomiting although rare.

There are other possible side effects of Brusal that can be more bothersome, but are thankfully less common. An allergic reaction to the compound can cause a swelling of the lips or tongue as well as a possible rash. Oddly enough, an allergic reaction can also lead to difficulty breathing. Less common but most commonly associated with high doses is chest pain, high blood pressure and an irregular heartbeat. If such side effects of Brusal begin to manifest use should be discontinued immediately. If ignored, these effects can become quite extreme. When the side effects of Brusal reach an extreme level, harsh shaking or trembling may occur. Anxiety, panic and an extremely fast and irregular heartbeat are all possible, and can be potentially fatal.

Brusal can be used safely, but it will require responsible use. At the same time, we are all unique individuals and will respond to varying medications differently. If harsh or severe effects of Brusal use begin to show for any reason, discontinue use. It is when such effects are ignored that trouble may arise. While many will be able to use the compound safely, if you cannot, simply reexamine your plan and search for better options. There is no reason to risk your health for a little extra fat loss.

Serious interactions of Brusal include:

  • amitriptyline
  • amoxapine
  • clomipramine
  • desipramine
  • dosulepin
  • doxepin
  • imipramine
  • isocarboxazid
  • linezolid
  • lofepramine
  • maprotiline
  • mianserin
  • nortriptyline
  • phenelzine
  • protriptyline
  • tranylcypromine
  • trazodone
  • trimipramine

Brusal has moderate interactions with at least 249 different drugs.

Mild Interactions of Brusal include:

The information presented does not contain all possible interactions from the use of this drug. Therefore, before using this product, tell your doctor or pharmacist of all the drugs you use. Keep a list of all your medications with you, and share the list of drugs with your doctor and pharmacist. Check with your doctor if you have health questions or concerns about asthma or asthma medications.


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