AccuNeb

AccuNeb

  • Active Ingredient: Albuterol
  • 100mcg
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What is AccuNeb?

The active ingredient of AccuNeb brand is albuterol. Albuterol is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs. Albuterol sulfate has a molecular weight of 576.71, and the molecular formula is (C13H21NO3)2•H2SO4. Albuterol sulfate is a white or practically white powder, freely soluble in water and slightly soluble in ethanol. The World Health Organization recommended name for Albuterol base is salbutamol. Each Albuterol sulfate tablet, for oral administration contains 2 or 4 mg of Albuterol as 2.4 or 4.8 mg of Albuterol sulfate, respectively. Each tablet also contains the following inactive ingredients: anhydrous lactose, magnesium stearate, pregelatinized (corn) starch, and sodium starch glycolate. The pharmacologic effects of beta-adrenergic agonist drugs, including Albuterol, are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. Albuterol has been shown in most controlled clinical trials to have more effect on the respiratory tract, in the form of bronchial smooth muscle relaxation, than isoproterenol at comparable doses while producing fewer cardiovascular effects. Albuterol is longer acting than isoproterenol in most patients by any route of administration because it is not a substrate for the cellular uptake processes for catecholamines nor for catechol-O-methyl transferase. Studies in laboratory animals (minipigs, rodents, and dogs) have demonstrated the occurrence of cardiac arrhythmias and sudden death (with histologic evidence of myocardial necrosis) when beta-agonists and methylxanthines are administered concurrently. The clinical significance of these findings is unknown. In other studies, the analysis of urine samples of patients given 8 mg of tritiated Albuterol orally showed that 76% of the dose was excreted over 3 days, with the majority of the dose being excreted within the first 24 hours. Sixty percent of this radioactivity was shown to be the metabolite. Feces collected over this period contained 4% of the administered dose.

Used for

AccuNeb is used to treat diseases such as: Asthma, acute, Asthma, Maintenance, Bronchiectasis, Bronchospasm Prophylaxis, COPD, Acute, COPD, Maintenance.

Side Effect

Possible side effects of AccuNeb include: tightness in the throat; hoarseness; irritability; Cough; swelling of the mouth or throat; unable to sleep; Bad, unusual, or unpleasant (after) taste.

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AccuNeb Dosage

This medicine comes as a liquid to inhale with a nebulizer (a machine that turns medication into a mist) or as an aerosol inhaler.

You should follow your doctor's instructions carefully when using this medicine.

The inhaler is typically used every four to six hours as needed to treat or prevent symptoms of lung disease. The nebulizer solution is typically used three to four times a day as needed.

The inhaler form of AccuNeb comes in canisters. Each canister provides 200 inhalations. You should throw away the canister after you've used the labeled number of inhalations, even if you think it still contains some medication.

Your inhaler may provide an attached counter that keeps track of the number of sprays you've used. You shouldn't try to change the numbers or remove the counter from the canister. When the number "020" appears on the counter, you should contact your doctor or pharmacist for a refill. When the number "000" appears, you shouldn't use the inhaler any longer.

If your inhaler doesn't contain a counter, you'll have to keep track of the number of inhalations you use. You can divide the number of inhalations in your inhaler by the number of inhalations you use each day to determine how many days your inhaler will last.

When using the inhaler for the first time, you should prime it by spraying four test sprays into the air, away from your face. Also, prime the inhaler if you haven't used it for two weeks or longer, or if you drop it.

Never use your inhaler to inhale any other type of medication. Your inhaler is designed for an AccuNeb canister only.

You should clean your inhaler or nebulizer on a regular basis. If you don't care for your inhaler properly, it can become blocked.

Q: How safe is an AccuNeb inhaler for asthma?

A: AccuNeb is a bronchodilator that relaxes muscles in the airways improving air flow to the lungs. AccuNeb inhalers are used to treat bronchospasm (wheezing and shortness of breath) in patients with lung conditions such as asthma. Patients with certain medical conditions like high blood pressure, heart disease, heart rhythm disorder, epilepsy, diabetes, or overactive thyroid have an increased chance of having an adverse reaction with AccuNeb. Rare but serious side effects have been reported with AccuNeb including chest tightness, chest pain, abnormal heart rhythm, nervousness, tremor, and increased blood pressure. Less serious side effects include headache, dizziness, nervousness, insomnia, cough, dry mouth, sore throat, muscle pain, and diarrhea. This is not a complete list of the side effects associated with AccuNeb. For more specific information, consult with your doctor or pharmacist. AccuNeb can have interactions with some medications particularly beta-blockers for high blood pressure. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your healthcare providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Burton Dunaway, PharmD

How should I use AccuNeb inhalation?

Use AccuNeb inhalation exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use AccuNeb inhalation in larger or smaller amounts or for longer than recommended.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

You may need to prime your AccuNeb inhaler device before the first use. Your medicine comes with directions for priming if needed. You may also need to shake your AccuNeb device just before each use.

Keeping your inhaler clean is important to ensure you are receiving the medication. Clean the plastic actuator with the canister removed at least once a week. Your medicine comes with directions for properly cleaning your device.

Follow all medication instructions very carefully.

Do not allow a young child to use AccuNeb inhalation without help from an adult.

The usual dose of AccuNeb inhalation is 2 inhalations every 4 to 6 hours. To prevent exercise-induced bronchospasm, use 2 inhalations 15 to 30 minutes before you exercise. The effects of AccuNeb inhalation should last about 4 to 6 hours.

Seek medical attention if you think your asthma medications are not working as well. An increased need for medication could be an early sign of a serious asthma attack.

Use the dose counter on your AccuNeb inhaler device and get your prescription refilled before you run out of medicine completely. Always use the new inhaler device provided with your refill. Do not float a medicine canister in water to see if it is empty.

Follow all product instructions on how to clean your AccuNeb inhaler device and mouthpiece. Do not try to clean or take apart the ProAir RespiClick inhaler device.

Asthma is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Store at room temperature away from moisture, heat, or cold temperatures.

Keep the AccuNeb canister away from open flame or high heat, such as in a car on a hot day. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.

Tell your doctor if you experience serious side effects of AccuNeb sulfate including bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new canister of this medicine; nervousness; shaking (tremor); headache; chest pain and fast, pounding, or irregular/uneven heartbeats (palpitations); low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

The usual starting dosage of AccuNeb sulfate for patients 2 to 12 years of age is 1.25 mg or 0.63 mg of AccuNeb sulfate inhalation solution administered 3 or 4 times daily, as needed, by nebulization. AccuNeb sulfate may interact with diuretics (water pills), digoxin, beta-blockers, antidepressants, MAO inhibitor, or other bronchodilators. Tell your doctor all medications you use. During pregnancy, AccuNeb sulfate should be used only when prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Our AccuNeb sulfate (AccuNeb sulfate inhalation solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Why is this medication prescribed?

AccuNeb is used to prevent and treat wheezing, difficulty breathing, chest tightness, and coughing caused by lung diseases such as asthma and chronic obstructive pulmonary disease (COPD; a group of diseases that affect the lungs and airways). AccuNeb is in a class of medications called bronchodilators. It works by relaxing and opening the air passages to the lungs to make breathing easier.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use AccuNeb only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2019 Cerner Multum, Inc. Version: 8.03.

AccuNeb sulfate (salbutamol sulfate)

Pharmacologic class: Sympathomimetic (beta2-adrenergic agonist)

Therapeutic class: Bronchodilator, antiasthmatic

Pregnancy risk category C

What should I do if I forget a dose?

If you have been told to use AccuNeb inhalation on a regular schedule, use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.

Dosage to prevent exercise-induced asthma

Adult dosage (ages 18–64 years)

  • The typical dosage is 2 inhalations taken by mouth, taken 15–30 minutes before starting exercise.

Child dosage (ages 4–17 years)

  • The typical dosage is 2 inhalations taken by mouth, taken 15–30 minutes before starting exercise.

Child dosage (ages 0–3 years)

The safety and effectiveness of this drug hasn’t been established in children younger than 4 years of age.

Senior dosage (ages 65 years and older)

Older adults may process drugs more slowly. A normal adult dose may cause levels of the drug to be higher than normal. If you’re a senior, you may need a lower dose or a different schedule.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

AccuNeb is used for short-term and long-term treatment. You can use this drug during flare-ups for your asthma. You might also need to take this drug long-term to relieve shortness of breath, wheezing, and coughing due to your asthma.

AccuNeb comes with risks if you don’t take it as prescribed.

If you stop taking the drug or don’t take it at all: If you don’t take AccuNeb at all, your asthma might get worse. This can lead to irreversible scarring of your airway. You’ll likely have shortness of breath, wheezing, and coughing.

If you miss doses or don’t take the drug on schedule: This drug is used on an as-needed basis. However, if you’re having acute flare-ups of asthma, you should be taking this drug 3 to 4 times a day. If you don’t take it on schedule during this time, you’ll likely have more trouble breathing.

If you take too much: You could have dangerous levels of the drug in your body. You may have the following symptoms:

  • fast heartbeat
  • arrhythmia (irregular heartbeat)
  • jitteriness

If you think you’ve taken too much of the drug, act right away. Call your doctor or local poison control center, or go to the nearest emergency room.

What to do if you miss a dose: This drug can be used as needed. If you’re using it on a scheduled basis (for asthma flare-ups) and miss a dose, take your dose as soon as you remember. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working: If this drug is working, your asthma symptoms should get better. You may not have as much shortness of breath, wheezing, or coughing.

Keep these considerations in mind if your doctor prescribes AccuNeb for you.

AccuNeb Warnings

You should keep AccuNeb with you at all times and get your prescription refilled before you run out of this medication.

AccuNeb can control symptoms of asthma and other lung diseases, but it doesn't cure them. You should not stop taking this medicine without first talking to your doctor.

This medicine can sometimes cause wheezing or breathing difficulties immediately after it's inhaled. You should call your doctor right away if this happens to you.

You should also tell your doctor if your symptoms worsen or if AccuNeb stops helping your symptoms.

Before taking AccuNeb, tell your healthcare provider if you have or have ever had:

Don't use your AccuNeb inhaler near a flame or source of heat. The inhaler can explode when exposed to very high temperatures.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of AccuNeb can be fatal.

Overdose symptoms may include dry mouth, tremors, chest pain, fast or irregular heartbeat, nausea, general ill feeling, seizure (convulsions), feeling light-headed or fainting.

AccuNeb

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Blood pressure drugs

In general, people with asthma shouldn’t use blood pressure medications called beta blockers. Beta blockers block the effects that AccuNeb has on your breathing. This can cause severe bronchospasms and more trouble breathing in people with asthma.

Examples of beta blockers include:

Using other blood pressure drugs such as diuretics (water pills) with AccuNeb can cause heart rhythm changes and potassium levels that drop lower than normal. If these medications are given together, your doctor should monitor your potassium levels.

Examples of diuretics include:

  • furosemide
  • hydrochlorothiazide
  • chlorthalidone
  • bumetanide

AccuNeb Overdose

If you suspect an overdose, contact a poison control center or emergency room immediately. You can get in touch with a poison control center at (800) 222-1222.

What should I avoid while using AccuNeb inhalation?

Rinse with water if this medicine gets in your eyes.

What Are Side Effects Associated with Using AccuNeb?

Common side effects of AccuNeb include:

Other side effects of AccuNeb include:

This is not a complete list of side effects and other serious side effects may occur. Call your doctor for information and medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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