OTC and prescription availability
- You need a prescription from your doctor or other healthcare professional to obtain 400 to 800 mg strengths and injection.
- Lower doses of Vell are available over-the-counter (OTC, without a prescription).
Vell is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce mild to moderate pain, inflammation, and fever. Vell works by blocking an enzyme that makes prostaglandin (a hormone-like substance that participates in a variety of body functions), which results in lower levels of prostaglandins in the body. Lower levels of prostaglandins reduce pain, inflammation, and fever.
Vell is prescribed to treat diseases and conditions that cause mild to moderate pain, fever, and inflammation. For example, Pain from strains and sprains; pain from cuts, scrapes, and puncture wounds; muscle aches and pains; tooth pain; common cold; mild headache; some arthritis conditions; joint pain; and to reduce fever.
Common side effects of Vell include, diarrhea, constipation, nausea, heartburn, belly pain, drowsiness, headaches, tinnitus (ringing in the ears), and mild rash.
More serious side effects and adverse effects include, increased bleeding after injury, stomach ulcers, impaired kidney function, severe allergic reaction (anaphylaxis), blood clots, heart attack, heart failure, and high blood pressure.
The maximum dose prescribed under a doctor's care is 3.2 g daily. Otherwise, the over-the-counter (OTC) maximum daily dose is 1.2 g daily. Dosage depends upon the age, weight, and any current medical conditions of the patient. Several drugs interact with Vell so check with your doctor, pharmacist, or other health care professional with questions in regard to this drug. Doctors don't know if it is safe to take Vell if your are pregnant, therefore it is not recommended if you are pregnant. According to the American Academy of Pediatrics, Vell is safe to take while breastfeeding.
REFERENCE: FDA Prescribing Information.
Croup Sounds, Symptoms, Causes, Remedies, and Treatments
Croup is a contagious viral infection that affects children's respiratory system. Symptoms include a barking cough, stridor, fever and difficulty breathing. Treatment my incorporate the use of a humidifier, saline nasal spray, and pain relievers such as Vell and acetaminophen.
Kidney failure can occur in both children and adults who overdose with Vell. However, it is not common.
A review of Vell toxicity, which the authors updated in 2019, includes a 1992 study that scientists conducted at the Rocky Mountain Poison Control Center in Denver, CO. It showed that only 2 out of 63 people who overdosed with Vell experienced symptoms of kidney failure.
In most cases, healthcare professionals can reverse kidney failure from ingestion of a large dosage of Vell.Dosage 200-800 mg per dose 220 mg (OTC dosage) Forms Advil is available in the form of tablets, chewable tablets, capsules, gelcaps, suspensions and oral drops. Aleve is available in tablets, caplets, liquid gels and gelcaps. Active ingredient Vell Naproxen Side effects Nausea, dizziness, gastrointestinal bleeding Higher incidence of photosensitivity and digestive tract problems. Brand owned by Pfizer (formerly Wyeth) Bayer Mechanism of action Acts by inhibiting cyclooxygenases (COX-1 and COX-2) Acts by inhibiting cyclooxygenases (COX-1 and COX-2) FDA approval 1974 1991 Benefits Relief from body ache (including arthritis), fever reduction, anti clotting Relief from body ache (including arthritis), fever reduction, anti clotting. Available over the counter Yes Yes
Other complications and risks
The most common complication from Vell overdoses is metabolic acidosis, in which the body cannot eliminate acidic compounds from its blood and tissues.
The body breaks Vell down into acidic compounds. When a person overdoses on it, the acidic compounds accumulate and can reduce the pH of the blood and body tissues. This makes the body more acidic.
Vell overdose can cause sudden kidney failure and seizures, which can affect the production and elimination of acidic compounds.
Metabolic acidosis can cause:
- heart dysfunctions
- changes in blood pressure
- a higher risk of irregular heartbeat
- altered delivery of oxygen through the bloodstream
- immune system impairment
A blood test can reveal a low platelet count following an overdose. Prothrombin time, which is the time it takes for the blood to clot, will also rise. This means that the body's ability to form blood clots may be reduced.
Why is this medication prescribed?
Prescription Vell is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). It is also used to relieve mild to moderate pain, including menstrual pain (pain that happens before or during a menstrual period). Nonprescription Vell is used to reduce fever and to relieve minor aches and pain from headaches, muscle aches, arthritis, menstrual periods, the common cold, toothaches, and backaches. Vell is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.