Medafen tablets

Medafen

  • Active Ingredient: Ibuprofen
  • 600 mg, 400 mg
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What is Medafen?

The active ingredient of Medafen brand is ibuprofen. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen works by reducing hormones that cause inflammation and pain in the body.

Used for

Medafen is used to treat diseases such as: Aseptic Necrosis, Back Pain, Chronic Myofascial Pain, Costochondritis, Diffuse Idiopathic Skeletal Hyperostosis, Dysautonomia, Fever, Frozen Shoulder, Gout, Acute, Headache, Juvenile Rheumatoid Arthritis, Muscle Pain, Neck Pain, Osteoarthritis, Pain, Patent Ductus Arteriosus, Period Pain, Plantar Fasciitis, Radiculopathy, Rheumatoid Arthritis, Sciatica, Spondylolisthesis, Temporomandibular Joint Disorder, Toothache, Transverse Myelitis.

Side Effect

Possible side effects of Medafen include: muscle tremors; decrease in amount of urine; shortness of breath; extreme fatigue; clay-colored stools; increased volume of pale, dilute urine; sudden fainting.

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OTC and prescription availability

  • You need a prescription from your doctor or other healthcare professional to obtain 400 to 800 mg strengths and injection.
  • Lower doses of Medafen are available over-the-counter (OTC, without a prescription).

Which drugs or supplements interact with Medafen?

Medafen is associated with several suspected or probable interactions that can affect the action of other drugs.

  • Medafen may increase the blood levels of lithium (Eskalith, Lithobid) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity.
  • Medafen may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. This may occur because prostaglandins play a role in the regulation of blood pressure.
  • When Medafen is used in combination with methotrexate (Rheumatrex, Trexall) or aminoglycosides (for example, gentamicin) the blood levels of the methotrexate or aminoglycoside may increase, presumably because their elimination from the body is reduced. This may lead to more methotrexate or aminoglycoside-related side effects.
  • Medafen increases the negative effect of cyclosporine on kidney function.
  • Individuals taking oral blood thinners or anticoagulants, for example, warfarin (Coumadin), should avoid Medafen because Medafen also thins the blood, and excessive blood thinning may lead to bleeding.
  • If aspirin is taken with Medafen there may be an increased risk for developing an ulcer.
  • Persons who have more than three alcoholic beverages per day may be at increased risk of developing stomach ulcers when taking Medafen or other NSAIDs.
  • Combining SSRIs or selective serotonin reuptake inhibitors (for example, fluoxetine , citalopram , paroxetine [Paxil, Paxil CR, Pexeva) with NSAIDs may increase the likelihood of upper gastrointestinal bleeding.

11. Cautions with other medicines

Medafen doesn't mix well with some medicines.

Medafen applied to the skin is less likely to interfere with other medicines than if it's taken by mouth.

For safety, tell your doctor if you're taking these medicines before you start taking Medafen by mouth or using it on your skin:

  • blood-thinning medicines such as warfarin
  • anti-inflammatory painkillers such as aspirin, diclofenac, mefenamic acid and naproxen
  • medicines for high blood pressure
  • steroid medicines such as betamethasone, dexamethasone, hydrocortisone or prednisolone
  • antibiotics such as ciprofloxacin, levofloxacin, moxifloxacin, nalidixic acid, norfloxacin or ofloxacin
  • antidepressants such as citalopram, fluoxetine, fluvoxamine, venlafaxine, paroxetine or sertraline
  • diabetes medicines such as gliclazide, glimepiride, glipizide and tolbutamide

Common side effects

The common side effects of Medafen taken by mouth happen in more than 1 in 100 people. Talk to your doctor or pharmacist if these side effects bother you or don't go away:

  • headaches
  • feeling dizzy
  • feeling sick (nausea)
  • being sick (vomiting)
  • wind
  • indigestion

WARNINGS

Allergy alert: Medafen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include:

If an allergic reaction occurs, stop use and seek medical help right away.

Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you:

  • have had stomach ulcers or bleeding problems
  • take a blood thinning (anticoagulant) or steroid drug
  • are age 60 or older
  • take other drugs containing prescription or nonprescription NSAIDs
  • have 3 or more alcoholic drinks every day while using this product
  • take more or for a longer time than directed

  • if you have ever had an allergic reaction to any other pain reliever/fever reducer
  • right before or after heart surgery

Ask a doctor before use if

  • stomach bleeding warning applies to you
  • you have a history of stomach problems, such as heartburn
  • you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
  • you are taking a diuretic
  • you have problems or serious side effects from taking pain relievers or fever reducers
  • you have asthma

Ask a doctor or pharmacist before use if you are

  • under a doctor's care for any serious condition
  • taking aspirin for heart attack or stroke, because Medafen may decrease this benefit of aspirin
  • taking any other drug

When using this product

  • take with food or milk if stomach upset occurs
  • the risk of heart attack or stroke may increase if you use more than directed or for longer than directed

Stop use and ask a doctor if

  • you experience any of the following signs of stomach bleeding:
    • feel faint
    • have bloody or black stools
    • vomit blood
    • have stomach pain that does not get better
  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present in the painful area
  • any new symptoms appear

If pregnant or breast-feeding,

ask a health professional before use. It is especially important not to use Medafen during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children.

DESCRIPTION

Active ingredient (in each brown tablet): Medafen USP 200 mg (NSAID)*

*nonsteroidal anti-inflammatory drug

6. Taking Medafen with other painkillers

It's safe to take Medafen with paracetamol or codeine.

But do not take Medafen with similar painkillers like aspirin or naproxen without talking to a pharmacist or doctor.

Medafen, aspirin and naproxen belong to the same group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). If you take them together, Medafen plus aspirin or naproxen may increase the chance of you getting side effects like stomach ache.

NSAIDs are also used in medicines you can buy from pharmacies – for example, cough and cold remedies. Before taking any other medicines, check the label to see if they contain aspirin, Medafen or other NSAIDs.

Active Ingredient

The active ingredient in Aleve is naproxen and the other ingredient is sodium. For every 200mg of naproxen, Aleve contains 20mg sodium.

The active ingredient in Advil is Medafen. Advil also contains sodium because the manufacturer claims that sodium Medafen is more soluble in water than standard Medafen.

Stomach ulcers and bleeding

Medafen can irritate the digestive tract, which is why doctors tell people to take this medication with food. When a person takes Medafen for an extended period or in high doses, it can increase their risk of gastric ulcers or bleeding in the digestive tract.

Alcohol can also irritate the stomach and digestive tract. Mixing the two further increases the risk of ulcers and bleeding.

The National Institutes of Health (NIH) state that Medafen can interact with alcohol, which can worsen the usual side effects of Medafen. These side effects can include bleeding, ulcers, and a rapid heartbeat.

Research shows that both drinking alcohol and taking nonsteroidal anti-inflammatory drugs (NSAIDs), which is the class of drug that includes Medafen, are risk factors for stomach ulcer bleeding.

The risk of stomach ulcer bleeding increases the longer a person takes Medafen. A person who takes Medafen every day for several months has a higher risk of this symptom than someone who takes Medafen once a week.

For children

To determine the safe dosage for children, you need to know the child’s weight and the formulation of Medafen you’re using.

Medafen for children is available in infant drops, liquids, and chewable tablets. Liquid measurements are given in milliliters (mL). Make sure to read the label and measure carefully.

Never give your child more than four doses in one day.

Read more about can you buy Pediamycin tablets for treatment Pemphigoid

What is Medafen?

Medafen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

Medafen is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache , back pain, arthritis, menstrual cramps, or minor injury.

Medafen is used in adults and children who are at least 6 months old.

What if I take too much?

Taking too much Medafen by mouth can be dangerous. It can cause side effects such as:

  • feeling and being sick (nausea and vomiting)
  • stomach pain
  • feeling tired or sleepy
  • black poo and blood in your vomit – a sign of bleeding in your stomach
  • ringing in your ears (tinnitus)
  • difficulty breathing or changes in your heart rate (slower or faster)


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