Celebra capsules

Celebra

  • Active Ingredient: Celecoxib
  • 200 mg, 100 mg
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What is Celebra?

The active ingredient of Celebra brand is celecoxib. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). Celecoxib works by reducing hormones that cause inflammation and pain in the body.

Used for

Celebra is used to treat diseases such as: Ankylosing Spondylitis, Familial Adenomatous Polyposis, Fibromatosis, Juvenile Rheumatoid Arthritis, Osteoarthritis, Pain, Period Pain, Rheumatoid Arthritis, Spondyloarthritis.

Side Effect

Possible side effects of Celebra include: depression; weakness or heaviness of the legs; high blood pressure; pain during sexual intercourse; tenderness in the stomach area; Back pain.

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Celebra was not carcinogenic in Sprague-Dawley rats given oral doses up to 200 mg/kg for males and 10 mg/kg for females (approximately 2-to 4-times the human exposure as measured by the AUC0-24 at 200 mg twice daily) or in mice given oral doses up to 25 mg/kg for males and 50 mg/kg for females (approximately equal to human exposure as measured by the AUC0-24 at 200 mg twice daily) for two years.

Pharmacokinetics

Celebra exhibits dose-proportional increase in exposure after oral administration up to 200 mg twice daily and less than proportional increase at higher doses. It has extensive distribution and high protein binding. It is primarily metabolized by CYP2C9 with a half-life of approximately 11 hours.

Storage And Handling

CELEBREX (Celebra) 50 mg capsules are white, with reverse printed white on red band of body and cap with markings of 7767 on the cap and 50 on the body, supplied as:

CELEBREX (Celebra) 100 mg capsules are white, with reverse printed white on blue band of body and cap with markings of 7767 on the cap and 100 on the body, supplied as:

CELEBREX (Celebra) 200 mg capsules are white, with reverse printed white on gold band with markings of 7767 on the cap and 200 on the body, supplied as:

CELEBREX (Celebra) 400 mg capsules are white, with reverse printed white on green band with markings of 7767 on the cap and 400 on the body, supplied as:

Metabolic

Frequency not reported: Increased blood urea nitrogen, increased creatinine phosphokinase, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, non-protein nitrogen increased, creatinine increased, alkaline phosphatase increased, weight increased, anorexia

Increased blood urea nitrogen, increased creatinine phosphokinase, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, non-protein nitrogen increased, creatinine increased, alkaline phosphatase increased, anorexia, and increased weight increase were reported in 0.1% to 1.9% of patients taking Celebra 100 to 200 mg twice a day or 200 mg once a day.

Read more about can you buy Zomepral capsules for GERD

Celebra

Pharmacologic class: Nonsteroidal cyclooxygenase-2 (COX-2) inhibitor, nonsteroidal anti-inflammatory drug (NSAID)

Therapeutic class: Antirheumatic

Pregnancy risk category C

Musculoskeletal

Arthralgia, arthrosis, bone disorder, accidental fracture, myalgia, neck stiffness, synovitis, and tendinitis were reported in 0.1% to 1.9% of patients taking Celebra 100 to 200 mg twice a day or 200 mg once a day. In the long-term polyp prevention studies in which exposure to Celebra was 400 to 800 mg per day for up to 3 years, epicondylitis or tendon rupture were reported in at least 0.1% of patients to less than 1% of patients.

Uncommon (0.1% to 1%): Epicondylitis, tendon rupture

Frequency not reported: Arthralgia, arthrosis, bone disorder, accidental fracture, myalgia, neck stiffness, synovitis, tendinitis

Generic Name: Celebra (SEL e KOX ib)Brand Names: CeleBREX

Medically reviewed by P. Thornton, DipPharm Last updated on Aug 1, 2019.

In Summary

Commonly reported side effects of Celebra include: diarrhea, hypertension, and abnormal hepatic function tests. Other side effects include: abdominal pain, dyspepsia, gastroesophageal reflux disease, peripheral edema, vomiting, and increased liver enzymes. See below for a comprehensive list of adverse effects.

What other drugs will affect Celebra?

Ask your doctor before using Celebra if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may cause you to bruise or bleed easily.

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • fluconazole;
  • lithium;
  • a blood thinner (warfarin, Coumadin, Jantoven);
  • heart or blood pressure medication, including a diuretic or "water pill"; or
  • steroid medicine (such as prednisone).

This list is not complete. Other drugs may interact with Celebra, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.


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