Paxon tablets


  • Active Ingredient: Buspirone
  • 10 mg, 5 mg
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What is Paxon?

The active ingredient of Paxon brand is buspirone. Buspirone is an anti-anxiety medicine that affects chemicals in the brain that may be unbalanced in people with anxiety. Each tablet, for oral administration, contains 5 mg, 7.5 mg, 10 mg, 15 mg or 30 mg of Buspirone hydrochloride, USP (equivalent to 4.6 mg, 6.9 mg, 9.1 mg, 13.7 mg and 27.4 mg of Buspirone free base, respectively). The 5 mg and 10 mg tablets are scored so they can be bisected. Thus, the 5 mg tablet can also provide a 2.5 mg dose, and the 10 mg tablet can provide a 5 mg dose. The 15 mg tablets are scored such that they may be bisected or trisected. Thus, a single tablet can provide the following doses: 15 mg (entire tablet), 10 mg (two-thirds of a tablet), 7.5 mg (one-half of a tablet), or 5 mg (one-third of a tablet). The 30 mg tablets are scored such that they may be bisected or trisected. Thus, a single tablet can provide the following doses: 30 mg (entire tablet), 20 mg (two-thirds of a tablet), 15 mg (one-half of a tablet), or 10 mg (one-third of a tablet). Buspirone hydrochloride tablets, USP contain the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate.

Used for

Paxon is used to treat diseases such as: Anxiety, Borderline Personality Disorder, Panic Disorder, Sexual Dysfunction, SSRI Induced.

Side Effect

Possible side effects of Paxon include: numbness, tingling, pain, or weakness in the hands or feet; sore throat; drowsiness (severe); decreased concentration; fast or pounding heartbeat; uncontrolled movements of the body; very small pupils of the eyes; fever.

How to Buy Paxon tablets online?

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In a study of steady-state pharmacokinetics in healthy volunteers, coadministration of Paxon (2.5 or 5 mg b.i.d.) with nefazodone (250 mg b.i.d.) resulted in marked increases in plasma Paxon concentrations (increases up to 20-fold in Cmax and up to 50-fold in AUC) and statistically significant decreases (about 50%) in plasma concentrations of the Paxon metabolite 1-PP. With 5 mg b.i.d. doses of Paxon, slight increases in AUC were observed for nefazodone (23%) and its metabolites hydroxynefazodone (HO-NEF) (17%) and meta-chlorophenylpiperazine (9%). Slight increases in Cmax were observed for nefazodone (8%) and its metabolite HO-NEF (11%).

Subjects receiving Paxon 5 mg b.i.d. and nefazodone 250 mg b.i.d experienced lightheadedness, asthenia, dizziness, and somnolence, adverse events also observed with either drug alone. If the two drugs are to be used in combination, a low dose of Paxon (e.g., 2.5 mg q.d.) is recommended. Subsequent dose adjustment of either drug should be based on clinical assessment.


Paxon ( Fig. 11-12 ), an azapirone (short for azaspirodecanedione) derivative structurally unrelated to the benzodiazepines, represents a unique class of antianxiety agents. Paxon has antianxiety effects that are therapeutically equivalent to the effects of diazepam, but it lacks the more prominent CNS depressant effects and the anticonvulsant and muscle relaxant properties of the benzodiazepines. In addition, Paxon does not augment the sedative effect of ethyl alcohol or other sedatives, and it has little effect on psychomotor or cognitive function. Physical dependence does not occur, and withdrawal does not occur at abrupt cessation. This drug has a more anxiolytic-selective profile than benzodiazepines, representing a major advance in antianxiety therapy and a useful alternative to benzodiazepines.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Heart or cardiovascular effects. Symptoms can include:
    • fast heart rate
    • palpitations (feeling like your heart is skipping a beat)
    • chest pain
    • low or high blood pressure
    • fainting
  • Trouble with coordination (controlling your movements)
  • Outbursts of anger
  • confusion
  • large pupils (the black centers of your eyes)
  • fast heart rate
  • high blood pressure
  • fever
  • excessive sweating
  • rigid muscles
  • nausea
  • vomiting
  • seizures

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Paxon oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with Paxon are listed below.


Paxon is an azaspirone that acts as a full agonist on the serotonin 1A (5HT 1A) autoreceptor and as a partial agonist on the postsynaptic 5-HT1A receptor. Positive results of the trials with SSRIs for SAD stimulated further research with drugs that have a serotonergic effect.

Clark and Agras (1991) randomized 34 musicians with SAD to receive either six weeks of Paxon, six weeks of placebo, five sessions of group CBT plus Paxon, or CBT with placebo. The average dose of Paxon was 32 mg. There was no difference between Paxon and placebo, whereas CBT was superior to both Paxon and placebo without psychotherapy. Munjack, Bruns, Baltazar, Brown, Leonard et al. (1991) conducted a 12-week open trial of Paxon (mean dose=48 mg/day) in 17 patients with GSAD. The overall response rate was 53% of the intent-to-treat sample.

Schneier, Saoud, Campeas, Fallon, Hollander et al. (1993) conducted another 12-week open trial with 21 patients with similar response rates (47%) to those obtained in Munjack and colleagues' study. Seventeen patients completed at least two weeks of treatment and were included in the analysis. Interestingly, responders received a higher average dose of Paxon than did nonresponders (56.9 vs. 38.3 mg/day). Van Vliet, den Boer, Westenberg, and Pian (1997) investigated further the efficacy of fixed-dose Paxon (30 mg/day) versus placebo in a 12-week placebo-controlled study of 30 patients with SAD. Only one patient receiving Paxon and another taking placebo were >

In contrast with the promising results of the open trials, neither of the two controlled trials of Paxon was able to show its efficacy as monotherapy for SAD. Additionally, the dosage of Paxon needed seems to be in the upper range (60 mg/day), which may limit its usefulness on the basis of side effects, such as nausea or headache. Although Paxon has not proven to be superior to placebo as monotherapy, a small trial conducted by van Ameringen, Mancini, and Wilson (1996) studied Paxon (doses range=30–60 mg/day; mean dose=45 mg/day) as an augmenting agent on 10 patients with GSAD with a partial response to an adequate trial of an SSRI during eight weeks. Although seven patients (70%) were considered responders according to CGI criteria, this approach has not been further studied.

What are Paxon and Xanax?

Paxon is used for the treatment of anxiety. Its mechanism of action is not clearly understood but may involve effects on the neurotransmitters serotonin and dopamine. Paxon may work by stimulating serotonin type 1A receptors on nerves, thereby altering the chemical messages that nerves receive. Unlike medications for anxiety of the benzodiazepine class, Paxon does not cause sedation.

Xanax (alprazolam) is an anti-anxiety medication in the benzodiazepine family, the same family that includes diazepam (Valium), clonazepam (Klonopin), lorazepam (Ativan), and flurazepam (Dalmane). Xanax and other benzodiazepines act by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain. GABA inhibits activity in the brain. It is believed that excessive activity in the brain may cause anxiety or other psychiatric disorders.

Rated Paxon (BuSpar) for Anxiety Report

I was taking bursprione for a month. It was was literally hell and still is. I had the worst panic/anxiety attack of my life which put me in the hospital. It took nearly 4 hrs for it to break. I've been off of it for a tad over a month and I'm still having withdrawals from it. Burning sensations in my brain, tremors constipation you name it. Ive nearly passed out while driving and had to pull over. My doctor states that "in on such a low dose" I'd really hate to see what a high dose does to someone. If your doctor recommends this "medication" to you.. I suggest finding a new doctor ASAP. Anyone having a bad experience, you're not alone.


In a study in normal volunteers, concomitant administration of Paxon and haloperidol resulted in increased serum haloperidol concentrations. The clinical significance of this finding is not clear.

Rated Paxon (BuSpar) for Anxiety Report

This drug caused severe headaches and asthma-like breathing problems which was really frightening.


There is one report suggesting that the concomitant use of Desyrel®# (trazodone hydrochloride) and Paxon may have caused 3- to 6-fold elevations on SGPT (ALT) in a few patients. In a similar study attempting to replicate this finding, no interactive effect on hepatic transaminases was identified.

High blood pressure drugs

Taking certain blood pressure drugs with Paxon can increase the levels of Paxon in your body. This raises your risk of side effects. Your doctor may change your dosage of Paxon if you’ll be taking it with one of these drugs.

Examples of these blood pressure drugs include:


After addition of Paxon to the diazepam dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) were observed for diazepam, but increases of about 15% were seen for nordiazepam, and minor adverse clinical effects (dizziness, headache, and nausea) were observed.

Rated Paxon (BuSpar) for Anxiety Report

Well I have always had anxiety problems since I was a teenager I ignored it by either drinking or smoking weed and I have made worse by depending on it to help me. Today I was having an anxiety attack and didn't know wat to do till I remembered my doctor prescribed the Paxon for me. So far so good I'm more relaxed and my mind isn't racing so we shall c how it works from here on out.

Read more about how to buy Zelapar tablets for treatment Depression

Paxon vs. Xanax Differences Between S >
  • Paxon vs. Xanax differences between side effects and uses
  • What are Paxon and Xanax?
  • What are the side effects of Paxon and Xanax?
  • What is the dosage for Paxon vs. Xanax?
  • What drugs interact with Paxon and Xanax?
  • Are Paxon and Xanax safe to take while pregnant and breastfeeding?

Paxon Warnings

You should not take Paxon if you are taking a monoamine oxidase inhibitor (MAOI), a type of drug used for treating depression.

Examples of MAOIs include phenelzine (Nardil) and tranylcypromine (Parnate).

Taking Paxon with MAOIs can cause a dangerous increase in blood pressure.

Research has shown that the safety of Paxon does not vary by age. For short-term use (no more than six weeks), it's as safe in people 65 and older as in other adults and in children six to 17.

However, long-term safety of Paxon in children is unknown.

Let your doctor know if you're taking other medications for anxiety.

Many anxiety medications can be dangerous if you stop taking them suddenly. They can cause a dangerous withdrawal reaction that could include anxiety, insomnia, abdominal pain, and seizure.

Switching from one of these drugs to Paxon will not prevent a withdrawal reaction because Paxon does not act like these other medications. Instead, you have to taper down the dose of the drugs gradually.

Your doctor should know if you have certain conditions so he or she can decide if Paxon is the right drug for you. They include:

  • Kidney disease
  • Liver disease
  • Drug or alcohol abuse
  • Pheochromocytoma (a rare tumor that causes high blood pressure)


Paxon hydrochloride tablets are indicated for the management of anxiety disorders or the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

The efficacy of Paxon hydrochloride tablets have been demonstrated in controlled clinical trials of outpatients whose diagnosis roughly corresponds to Generalized Anxiety Disorder (GAD). Many of the patients enrolled in these studies also had coexisting depressive symptoms and Paxon hydrochloride tablets relieved anxiety in the presence of these coexisting depressive symptoms. The patients evaluated in these studies had experienced symptoms for periods of 1 month to over 1 year prior to the study, with an average symptom duration of 6 months. Generalized Anxiety Disorder (300.02) is described in the American Psychiatric Association’s Diagnostic and Statistical Manual, III1 as follows:

Generalized, persistent anxiety (of at least 1 month continual duration), manifested by symptoms from three of the four following categories:

Rated Paxon (BuSpar) for Anxiety Report

This medication actually worked for me. Like reviews below say it works for some and not for others. Just like all other medication. I was hesitant to go on it at first however it’s been helping me manage my anxiety to a point where I can focus on it and help myself. Only side effect I’ve noticed is super vivid dreams. The most vivid dreams I’ve ever had. Some nightmares but all tolerable.

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