Idoxen tablets


  • Active Ingredient: Venlafaxine
  • 150 mg, 75 mg, 37.5 mg
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What is Idoxen?

The active ingredient of Idoxen brand is venlafaxine. Venlafaxine is a selective serotonin and norepinephrine reuptake inhibitor (SNRIs) antidepressant. Venlafaxine affects chemicals in the brain that may be unbalanced in people with depression.

Used for

Idoxen is used to treat diseases such as: Anxiety, Anxiety and Stress, Autism, Bipolar Disorder, Bulimia, Cataplexy, Depression, Dissociative Identity Disorder, Fibromyalgia, Generalized Anxiety Disorder, Hot Flashes, Irritable Bowel Syndrome, Major Depressive Disorder, Migraine, Obsessive Compulsive Disorder, Panic Disorder, Post Traumatic Stress Disorder, Postpartum Depression, Premenstrual Dysphoric Disorder, Social Anxiety Disorder, Somatoform Pain Disorder, Vulvodynia.

Side Effect

Possible side effects of Idoxen include: heartburn; diarrhea; restlessness; nervousness; mood or mental changes; poor coordination; tingling, burning, or prickly sensations.

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Q: Does Effexor increase dream activity?

A: Effexor (Idoxen) is in a drug class called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). Effexor is used in the treatment of depression. In addition, Effexor XR (Idoxen long-acting) is used to treat generalized anxiety disorder (GAD), social anxiety disorder, and panic disorder. Effexor works by increasing the naturally occurring brain substances serotonin and norepinephrine, which in turn helps maintain mental balance. The most common side effects with Effexor are weakness (lack of energy and strength); sweating; nausea; constipation; loss of appetite; vomiting, sleepiness; dry mouth; dizziness; nervousness; anxiety; tremor; blurred vision; abnormal ejaculation/orgasm and impotence in men. Abnormal dreams are is reported side effect with Effexor. The most common side effects with Effexor XR are abnormal ejaculation; nausea; dry mouth; loss of appetite; dizziness; sleepiness; abnormal dreams; sweating; impotence in men; failure to achieve orgasm in women; decreased sexual desire; constipation; excessive gas; insomnia; nervousness; tremor; abnormal vision; high blood pressure; widening of blood vessels; yawning; weakness (lack of energy and strength); and insomnia. These are not complete lists of the side effects associated with Effexor and Effexor XR When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Tell your health care provider about any negative side effects from prescription drugs. You can also report them to the U.S. Food and Drug Administration by visiting or by calling 1-800-FDA-1088. Dreaming can be affected by many factors. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Derek Dore, PharmD

Effects Of Other Drugs On Effexor XR

Figure 1: Effect of interacting drugs on the pharmacokinetics of Idoxen and active metabolite O-desmethylIdoxen (ODV).


Do not stop taking Idoxen suddenly, or without talking to your doctor first.

Idoxen isn't any better or worse than other antidepressants. However, sometimes people respond better to one antidepressant than to another. If you aren't feeling any better after 6 weeks, talk to your doctor.

Antidepressants, including Idoxen, are just one of several approaches to treating depression or anxiety.

Other potential treatments for depression include:

  • talking therapy (such as cognitive behavioural therapy)
  • exercise programmes
  • help to get a good night's rest if sleep is a problem

Other potential treatments for anxiety include:

  • talking therapy (such as cognitive behavioural therapy)
  • joining a self-help group
  • using relaxation techniques

Choosing a treatment that's most suitable for you depends on:

  • how long you've had depression or anxiety and your symptoms
  • whether previous treatment has worked
  • how likely you are to stick with your treatment
  • the potential side effects
  • your preferences and priorities

If you're interested in any of these treatments, talk to your doctor.

There's no firm evidence to suggest that taking Idoxen will reduce fertility in men, but it may interfere with the menstrual cycle in women.

Speak to a pharmacist or your doctor if you're trying to get pregnant. They may want to review your treatment.

You can eat and drink normally while taking Idoxen.

Idoxen can make you feel less hungry than usual, so you may lose weight when you start taking it. Some people might find they gain weight.

If you start to have problems with your weight while taking Idoxen, talk to your doctor or pharmacist.

The good effects of Idoxen may, after a while, improve your sex life as your mood lifts and you become interested in life and relationships again.

Some of the possible negative effects include:

  • men might have problems with getting an erection, or with ejaculating
  • women might have some vaginal bleeding
  • both men and women might find they don't reach orgasm the same way as before
  • you may have a lower sex drive

Sexual side effects usually pass after the first couple of weeks. However, very rarely, they can be long lasting and may not get better even after stopping the medicine.

If these happen and are a problem for you, go back to your doctor to see if there's another treatment you can try.

Idoxen will not affect contraception including the combined pill or emergency contraception.

Some people can't concentrate properly while they're taking Idoxen. It might be best to stop driving and cycling for the first few days of treatment until you know how this medicine makes you feel.

You can drink alcohol while taking Idoxen but it may make you feel sleepy. It might be best to stop drinking alcohol during the first few days of treatment until you see how this medicine affects you.

Cannabis with Idoxen can give you a fast heartbeat. Cannabis can also make drowsiness worse with Idoxen, especially in people who have just started taking it.

Methadone can make sleepiness worse with Idoxen. It can be potentially dangerous to take Idoxen with:

  • stimulants like MDMA (ecstasy) or cocaine
  • hallucinogens like LSD
  • novel psychoactive substances (which used to be known as legal highs) like mephedrone

Rated Idoxen for Chronic fatigue syndrome (CFS; CF >Report

I can NOT recommend taking this due the horrible side effects and reactions to my stomach . constant bouts of Gastritist ever since I began taking this drug and excoriating stomach pain . Enough is enough . it is not for me !!

Serious side effects

It is not common, but some people (less than 1 in 100) may have serious side effects when taking Idoxen.

Go to A&E immediately if you get:

  • chest pain or pressure, shortness of breath, or a fast or irregular heart beat
  • severe dizziness or passing out
  • any bleeding that is very bad or that you cannot stop such as cuts or nose bleeds that don't stop within 10 minutes

Call your doctor straight away if experience:

  • constant headaches, long-lasting confusion or weakness, or frequent muscle cramps can all be signs of low sodium levels in your blood - in severe cases low sodium levels can lead to seizures
  • feelings of euphoria, excessive enthusiasm or excitement, or a feeling of restlessness that means you can't sit or stand still
  • unexplained muscle pain or weakness
  • yellow skin or the whites of your eyes turn yellow - this can be a sign of liver problems
  • any changes in your eyesight, like blurred vision or dilated pupils
  • vomiting blood or dark vomit, coughing up blood, blood in your pee, black or red poo - these can be signs of bleeding from the gut
  • bleeding from the gums or bruises that appear without a reason or that get bigger
  • thoughts about harming yourself or ending your life

Book an appointment with your doctor if you experience:

  • weight gain or weight loss without trying
  • changes in your periods such as heavy bleeding, spotting, or bleeding between periods

What Other Drugs Interact with Idoxen (Zovirax)?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of this medicine or any drug before seeking medical advice from your doctor, healthcare provider or pharmacist first. To do so may result in serious consequences or side effects.

Severe Interactions of Idoxen include:

  • iobenguane I 123
  • isocarboxazid
  • phenelzine
  • procarbazine
  • selegiline
  • tranylcypromine

Idoxen has serious interactions with at least 69 different drugs.

Idoxen has moderate interactions with at least 172 different drugs.

Idoxen has mild interactions with at least 35 different drugs.

Idoxen has mild interactions with at least 65 different drugs.This document does not contain all possible interactions from the use of this medication. Therefore, before using this drug, tell your doctor or pharmacist of all the drugs you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

Idoxen and Other Interactions

Since Idoxen can induce sleepiness or hinder your ability to think clearly or react quickly, do not drive or operate heavy machinery until you know how Effexor affects you.

Your doctor needs to know about all the medications you take, whether prescription or over-the-counter, vitamins, illegal or recreational drugs, and dietary or herbal supplements, as they can affect how Effexor works, and vice-versa.

Idoxen interacts with the following drugs, which should not be taken with Effexor or taken only under close medical supervision:

How it works

Idoxen belongs to a class of antidepressant drugs called serotonin norepinephrine reuptake inhibitors (SNRIs). A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

SNRIs work by increasing the levels of substances called serotonin and norepinephrine in your brain. Having more serotonin and norepinephrine in your brain can improve your symptoms of depression and anxiety.

Idoxen oral tablet may cause drowsiness. It may also affect your ability to make decisions, think clearly, or react quickly. You should not drive, use heavy machinery, or do things that require you to be alert until you know you can function normally. Idoxen may also cause other side effects.

Q: What side effects does Effexor cause?

A: Effexor (Idoxen) is a medication that is used to treat depression. It is in a class of medications called serotonin-norepinephrine reuptake inhibitors. When the levels of serotonin or norepinephrine become unbalanced, it can cause a variety of conditions, including depression. Effexor helps to block the reuptake of serotonin and norepinephrine so that more remains in the space between the brain's nerve cells helping to alleviate the symptoms. The prescribing information for Effexor lists the following as side effects of the medication: nausea, headache, drowsiness, dry mouth, insomnia, loss of appetite, high blood pressure, sexual side effects, and anxiety. The prescribing information does not note any long-term effects of this medication. However, it has been found that some people who use this drug for long periods of time run the risk of becoming dependent on it. Withdrawal effects, which can last as long as two to four months, can include aggression, anxiety, blurred vision, problems concentrating, constipation, and fatigue. When you are ready to come off this medication, physicians recommend a gradual tapering off of the dosage amount over a period of time, and they will provide specific instructions on how to go about it. For more information on Effexor, visit // For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Lori Poulin, PharmD

What Is Idoxen (Effexor, Effexor XR) and How Does It Work?

Idoxen is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living. It may also decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Idoxen is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

Idoxen may also be used to treat hot flashes that occur with menopause.

Idoxen is available under the following different brand names: Effexor, and Effexor XR.

Q: My daughter is trying to wean herself off of Effexor, but she's going through crying jags and nervousness. What's the best way to wean off Effexor and onto another medicine, such as Paxil?

A: All medications for your daughter should be taken exactly as prescribed by your daughter's physician. She should not stop taking or decrease the dose of her medication without first talking to her physician. If her physician decides to discontinue the medication, then he or she should provide your daughter with instructions on how to wean herself off of it. Effexor (Idoxen) is classified as a serotonin/norepinephrine reuptake inhibitor antidepressant. It's approved for the treatment of depression, anxiety disorders, and panic disorders. The manufacturer recommendeds that patients gradually reduce the dosage, rather than abruptly stopping the medication. If intolerable symptoms occur while decreasing the dose or after the medication has been stopped, then the physician may want to consider resuming the previous dosage and decreasing more gradually. Tapering of dosages should be individualized for each patient and done under the supervision of the treating physician. Dose reduction or discontinuation of Effexor can include the following symptoms: agitation, anxiety, anorexia, confusion, impaired coordination and balance, diarrhea, dizziness, dry mouth, dysphoric mood (unpleasant or uncomfortable mood), fasciculation (muscle twitch), fatigue, flu-like symptoms, headaches, hypomania, insomnia, nausea, nervousness, nightmares, sensory disturbances, somnolence, sweating, tremor, vertigo, and vomiting. Please keep in mind that these are only possible symptoms that have been seen, and they are not guaranteed to occur. Jennyfer Marsico, RPh

Rated Idoxen for Depression Report

This medication is effective. Make sure you get brand name Efexor XL or Effexor XR, i got given (unbrandad) generic versions of this medication and the side effects were unbearable, BECAREFUL

What is the most important information I should know about Idoxen?

Do not use Idoxen within 7 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Do not stop using Idoxen without first talking to your doctor. Idoxen

Idoxen is a phenylethylamine derivative which produces a potent blockade of both serotonin and noradrenaline reuptake. In this respect the pharmacological properties of Idoxen resemble those of clomipramine. However, unlike clomipramine and other tricyclic antidepressants, Idoxen has a negligible affinity for other neurotransmitter receptor sites and so lacks sedative and anticholinergic effects. Idoxen is classified as a selective serotonin and noradrenaline reuptake inhibitor (SNRI). Idoxen has been studied in both inpatients and outpatients with major depression and compared with placebo and active comparators. Current studies suggest that it is more effective than placebo and at least of equal efficacy to other available antidepressant drugs. Idoxen also appears to be effective in depressed inpatients, perhaps more so than fluoxetine ( Clerc, Ruimy, & Verdeau-Pailles, 1994; Feighner, 1994 ).

Idoxen has a wider dosage range than SSRIs, from 75 mg to 375 mg daily, in two divided doses. Higher doses are associated with a greater incidence of adverse effects. The usual starting dose of Idoxen is 75 mg daily which may be sufficient for many patients. Upward titration can be considered where there is insufficient response, or if a faster onset of therapeutic activity is needed.

The adverse effect profile of Idoxen resembles that of SSRIs, with the most common adverse effects being nausea, headache, insomnia, and sexual dysfunction. Idoxen occasionally causes postural hypotension but, in addition, dose-related increases in blood pressure can occur. Blood pressure monitoring may be advisable in patients receiving more than 200 mg of Idoxen daily. Sudden discontinuation of Idoxen has been associated with symptoms of fatigue, nausea, and dizziness. It is recommended that the dose should be reduced gradually over at least a one week period. Preliminary evidence suggests that Idoxen is less toxic in overdose than tricyclic antidepressants ( Feighner, 1994 ).

Rated Idoxen for Depression Report

My doctor put me 75 mg for depression. After 3 doses I chose to stop taking. I was completely out of it and could not function at all. I could barely stay awake and I felt numb all over. 2 days later the numb feeling comes and goes. After reading up on Idoxen I am not sure why my doctor even put me on something like this initially without trying anything else first.

Serotonin and Norepinephrine Reuptake Inhibitors

Idoxen , desIdoxen, and duloxetine are marketed representatives of antidepressants whose mechanism of action is serotonin and norepinephrine transporter antagonism (at higher doses, paroxetine, usually classified as an SSRI, acts as a serotonin and norepinephrine reuptake inhibitor). Idoxen, approved for use in adult depression, generalized anxiety disorder, and social phobia, is also a weak inhibitor of dopamine reuptake but has little affinity for other neuroreceptors. Idoxen is metabolized principally by the cytochrome P-450 2D6 system to O-desmethylIdoxen, also an active serotonin and norepinephrine reuptake inhibitor. The elimination half-lives of Idoxen and its metabolite are 5 and 11 hours, respectively. Two large-scale, controlled, multicenter FDA pediatric exclusivity trials of Idoxen for pediatric depression failed to show efficacy at doses ranging from 37.5 to 225 mg daily in 6- to 17-year-olds ( U.S. FDA, 2003 ). Careful analysis revealed growth deceleration, hyperlipidemia, and hypertension in the treated group.

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