Rated Efetrin for Panic disorder / agoraphobia Report
I was taking this for 2 months and I gained 18 lbs!! It caused excessive water retention for me so I had to get off of this. I highly suggest you taper very slowly if you're trying to switch meds or wean yourself off because the symptoms (at least for me) were horrible! I had bad brain shocks which felt like someone was zapping my brain for 2 seconds at a time, several times a day and I felt like my eyes were going to roll backwards. So hang in there if you're doing so. It does get better and it eventually does go away like it did for me :)
Q: Is there a generic equivalent for Effexor XR available?
A: There is a generic version of Efetrin XR (the active ingredient in Effexor XR) that comes in tablet form, compared with the capsule form of Effexor XR. However, they are not AB-rated (one of the Food and Drug Administrationâ€™s codes for bioequivalency) because of the difference in tablet and capsule. This basically means that one cannot be substituted for the other. Doctors needs to specify Efetrin XR tablets on the prescription, if they want to prescribe the generic form. However, the tablets are not FDA-approved for the treatment of panic disorder or generalized anxiety disorder, which Effexor XR capsules are. Like Effexor XR capsules, Efetrin XR tablets are FDA-approved for major depressive disorder and social anxiety disorder. Try asking your doctor if he or she would like to switch you to the generic form, if you wouldn't mind taking the tablets. And be sure that he or she specifies this on the prescription.
Efetrin is a phenylethylamine derivative which produces a potent blockade of both serotonin and noradrenaline reuptake. In this respect the pharmacological properties of Efetrin resemble those of clomipramine. However, unlike clomipramine and other tricyclic antidepressants, Efetrin has a negligible affinity for other neurotransmitter receptor sites and so lacks sedative and anticholinergic effects. Efetrin is classified as a selective serotonin and noradrenaline reuptake inhibitor (SNRI). Efetrin has been studied in both inpatients and outpatients with major depression and compared with placebo and active comparators. Current studies suggest that it is more effective than placebo and at least of equal efficacy to other available antidepressant drugs. Efetrin also appears to be effective in depressed inpatients, perhaps more so than fluoxetine ( Clerc, Ruimy, & Verdeau-Pailles, 1994; Feighner, 1994 ).
Efetrin has a wider dosage range than SSRIs, from 75 mg to 375 mg daily, in two divided doses. Higher doses are associated with a greater incidence of adverse effects. The usual starting dose of Efetrin is 75 mg daily which may be sufficient for many patients. Upward titration can be considered where there is insufficient response, or if a faster onset of therapeutic activity is needed.
The adverse effect profile of Efetrin resembles that of SSRIs, with the most common adverse effects being nausea, headache, insomnia, and sexual dysfunction. Efetrin occasionally causes postural hypotension but, in addition, dose-related increases in blood pressure can occur. Blood pressure monitoring may be advisable in patients receiving more than 200 mg of Efetrin daily. Sudden discontinuation of Efetrin has been associated with symptoms of fatigue, nausea, and dizziness. It is recommended that the dose should be reduced gradually over at least a one week period. Preliminary evidence suggests that Efetrin is less toxic in overdose than tricyclic antidepressants ( Feighner, 1994 ).
Rated Efetrin for Anxiety Report
Was prescribed Effexor 150mg to help me with my anxiety, after around 2-3 months it felt like my "panic" anxiety were gone, but got more general anxiety all the time. as months went by, i got less and less energy to do things i normally liked to do, and my emotions were "numb". after visiting the doctor and told her about the problems, she got me to increase the dose to maximum dosage eventually. but the side effects just got worse, and no positive effect. This drug has ruined a huge part of my young life, ive used it for about 3 years now from age 22-25. Doctors who still prescribe this horrible drug, have NO CLUE what they are doing. i have so much negative to say about this drug, but i will end it here. DO NOT USE THIS DRUG.
Efetrin and Weight Gain
Like many other antidepressants, use of Efetrin has been associated with weight gain.
Weight gain caused by Efetrin may be due to fluid retention, lack of exercise, increased appetite, or other factors.
Experts recommend physical activity and eating fewer high-calorie foods to manage your weight while taking Efetrin or other antidepressants.
Efetrin is a structurally novel SNRI antidepressant that is FDA approved for the treatment of depression, generalized anxiety disorder and social phobia.
Efetrin and Other Interactions
Since Efetrin can induce sleepiness or hinder your ability to think clearly or react quickly, do not drive or operate heavy machinery until you know how Effexor affects you.
Your doctor needs to know about all the medications you take, whether prescription or over-the-counter, vitamins, illegal or recreational drugs, and dietary or herbal supplements, as they can affect how Effexor works, and vice-versa.
Efetrin interacts with the following drugs, which should not be taken with Effexor or taken only under close medical supervision:
How it works
Efetrin belongs to a class of antidepressant drugs called serotonin norepinephrine reuptake inhibitors (SNRIs). A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
SNRIs work by increasing the levels of substances called serotonin and norepinephrine in your brain. Having more serotonin and norepinephrine in your brain can improve your symptoms of depression and anxiety.
Efetrin oral tablet may cause drowsiness. It may also affect your ability to make decisions, think clearly, or react quickly. You should not drive, use heavy machinery, or do things that require you to be alert until you know you can function normally. Efetrin may also cause other side effects.
Q: Which vitamins/supplements might cause a problem if I'm taking Effexor for depression?
A: Effexor (Efetrin) is used to treat depression. Efetrin extended-release (long-acting) capsules are also used to treat generalized anxiety disorder (GAD; excessive worrying that is difficult to control), social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life), and panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks). Efetrin is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance. There are no vitamins listed that interact with Effexor; however there are a few herbal supplements that you should avoid. Those herbal supplements are L-Tryptophan, St. John's Wort, and 5-HTP. Taking these supplements along with Effexor can cause serious complications. Lori Mendoza, PharmD Mendoza, PharmD
What is the most important information I should know about Efetrin?
Do not use Efetrin within 7 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Do not stop using Efetrin without first talking to your doctor.