Anksilon tablets


  • Active Ingredient: Buspirone
  • 10 mg, 5 mg
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What is Anksilon?

The active ingredient of Anksilon brand is buspirone. Buspirone is an anti-anxiety medicine that affects chemicals in the brain that may be unbalanced in people with anxiety. Each tablet, for oral administration, contains 5 mg, 7.5 mg, 10 mg, 15 mg or 30 mg of Buspirone hydrochloride, USP (equivalent to 4.6 mg, 6.9 mg, 9.1 mg, 13.7 mg and 27.4 mg of Buspirone free base, respectively). The 5 mg and 10 mg tablets are scored so they can be bisected. Thus, the 5 mg tablet can also provide a 2.5 mg dose, and the 10 mg tablet can provide a 5 mg dose. The 15 mg tablets are scored such that they may be bisected or trisected. Thus, a single tablet can provide the following doses: 15 mg (entire tablet), 10 mg (two-thirds of a tablet), 7.5 mg (one-half of a tablet), or 5 mg (one-third of a tablet). The 30 mg tablets are scored such that they may be bisected or trisected. Thus, a single tablet can provide the following doses: 30 mg (entire tablet), 20 mg (two-thirds of a tablet), 15 mg (one-half of a tablet), or 10 mg (one-third of a tablet). Buspirone hydrochloride tablets, USP contain the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate.

Used for

Anksilon is used to treat diseases such as: Anxiety, Borderline Personality Disorder, Panic Disorder, Sexual Dysfunction, SSRI Induced.

Side Effect

Possible side effects of Anksilon include: Chest pain; Restlessness, nervousness, or unusual excitement; Blurred vision; decreased concentration; mental depression; drowsiness (severe).

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The recommended initial dose is 15 mg daily (7.5 mg b.i.d.). To achieve an optimal therapeutic response, at intervals of 2 to 3 days the dosage may be increased 5 mg per day, as needed. The maximum daily dosage should not exceed 60 mg per day. In clinical trials allowing dose titration, divided doses of 20 mg to 30 mg per day were commonly employed.

The bioavailability of Anksilon is increased when given with food as compared to the fasted state (see CLINICAL PHARMACOLOGY). Consequently, patients should take Anksilon in a consistent manner with regard to the timing of dosing; either always with or always without food.

When Anksilon is to be given with a potent inhibitor of CYP3A4, the dosage recommendations described in the DRUG INTERACTIONS section should be followed.

Drug/Laboratory Test Interactions

Anksilon hydrochloride may interfere with the urinary metanephrine/catecholamine assay. It has been mistakenly read as metanephrine during routine assay testing for pheochromocytoma, resulting in a false positive laboratory result. Anksilon hydrochloride should therefore be discontinued for at least 48 hours prior to undergoing a urine collection for catecholamines.

Can Anksilon cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with Anksilon. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Rated Anksilon (BuSpar) for Anxiety Report

I am on 30 mg of buspar twice a day and have been for about a month. I am 19. My anxiety has gotten somewhat better I think. I find myself wanting to talk to people, but I still can't bring myself to :') I feel kinda like a zombie still. It was kinda bad when I first started. (5mg twice a day. Then 15mg. Then 30 mg). I think it's helped, but I am not sure. I was in a major transition period when I began the medicine so it may be possible that my zombie like state is due to that.

Use In Patients With Impaired Hepatic Or Renal Function

Anksilon is metabolized by the liver and excreted by the kidneys. A pharmacokinetic study in patients with impaired hepatic or renal function demonstrated increased plasma levels and a lengthened half-life of Anksilon. Therefore, the administration of Anksilon hydrochloride tablets to patients with severe hepatic or renal impairment cannot be recommended (see CLINICAL PHARMACOLOGY).

Michael Stewart, Reviewed by Sid Dajani | Last edited 27 Sep 2019 | Certified by The Information Standard

Most people are prescribed Anksilon tablets for short periods of time only.

Taking Anksilon may make you feel sleepy. It may also increase the time it takes for you to react, so it can impair your judgement. If this happens, do not drive and do not use tools or machines.

Do not drink any alcohol or large amounts of grapefruit juice while you are on Anksilon.

What special dietary instructions should I follow?

Avoid drinking large amounts of grapefruit juice while taking Anksilon.

Anksilon Warnings

You should not take Anksilon if you are taking a monoamine oxidase inhibitor (MAOI), a type of drug used for treating depression.

Examples of MAOIs include phenelzine (Nardil) and tranylcypromine (Parnate).

Taking Anksilon with MAOIs can cause a dangerous increase in blood pressure.

Research has shown that the safety of Anksilon does not vary by age. For short-term use (no more than six weeks), it's as safe in people 65 and older as in other adults and in children six to 17.

However, long-term safety of Anksilon in children is unknown.

Let your doctor know if you're taking other medications for anxiety.

Many anxiety medications can be dangerous if you stop taking them suddenly. They can cause a dangerous withdrawal reaction that could include anxiety, insomnia, abdominal pain, and seizure.

Switching from one of these drugs to Anksilon will not prevent a withdrawal reaction because Anksilon does not act like these other medications. Instead, you have to taper down the dose of the drugs gradually.

Your doctor should know if you have certain conditions so he or she can decide if Anksilon is the right drug for you. They include:

  • Kidney disease
  • Liver disease
  • Drug or alcohol abuse
  • Pheochromocytoma (a rare tumor that causes high blood pressure)

Anksilon - is it available in extended (slow) release tablets?

Updated 7 May 2018 • 1 answer

What Is Anksilon (BuSpar)?

Anksilon is a prescription medication used to treat anxiety.

It belongs to a group of anti-anxiety drugs called anxiolytics, but it seems to work somewhat differently than other drugs in the class.

Though researchers don't know exactly how Anksilon reduces anxiety, they believe it competes with serotonin and dopamine, which are neurotransmitters (chemical brain messengers) involved with causing anxiety symptoms.

Anksilon isn't for treating occasional stress associated with everyday life. Rather, doctors prescribe Anksilon for anxiety disorder and short-term relief of anxiety symptoms.

You may be diagnosed with anxiety disorder if you have at least one full month of anxiety symptoms such as shakiness, tension, irritability, dizziness, worry, fear, upset stomach, and trouble sleeping.

The Food and Drug Administration (FDA) approved Anksilon in 1986 for the drug manufacturer Bristol-Myers Squibb, under the brand name BuSpar.

In 2001, the FDA approved a generic version of Anksilon for several drug manufacturers, and Bristol-Myers Squibb discontinued the brand name BuSpar.

Recently, researchers began studying other possible uses for Anksilon.

A 2013 study published in the journal International Review of Neurobiology found that Anksilon may be an effective treatment for Tourette syndrome, a brain disorder that causes people to make uncontrolled and repetitive movements and sounds (tics).

An earlier study, published in 2011 in the journal Therapeutic Advances in Neurological Disorders, also found that Anksilon may reduce the frequency and severity of Tourette syndrome tics.

HIV drugs

Taking certain drugs used to treat HIV with Anksilon can increase the levels of Anksilon in your body. This raises your risk of side effects. Your doctor may change your dosage of Anksilon if you’ll be taking it with one of these drugs.

Examples of these HIV drugs include:

  • ritonavir
  • atazanavir
  • darunavir
  • lopinavir/ritonavir

Anksilon Interactions

Some drugs may affect the way Anksilon works, and Anksilon may affect other drugs you are taking.

It's very important to let your doctor know about all drugs you are taking, including over-the-counter drugs, vitamins, and supplements.

Medications that are known to interact with Anksilon include:

  • MAOIs
  • Selective serotonin reuptake inhibitors (SSRIs) such as nefazodone (Serzone) and trazodone (Oleptro)
  • The blood thinner warfarin (Coumadin)
  • Drugs used to treat seizures, such as phenytoin (Dilantin) and carbamazepine (Tegretol)
  • Benzodiazepines that are used to treat anxiety and insomnia, such as diazepam (Valium) and triazolam (Halcion)
  • Muscle relaxants like cyclobenzaprine (Flexeril)
  • Drugs used to treat fungal infections, including itraconazole (Sporanox, Onmel), itraconazole (Sporanox), and ketoconazole (Nizoral)
  • Certain antibiotics, including erythromycin (E.E.S., E-Mycin, Erythrocin) and rifampin (Rifadin, Rimactane)
  • Steroids such as prednisone
  • The heartburn drug cimetidine (Tagamet)
  • The HIV drug ritonavir (Norvir)
  • Drugs used to treat high blood pressure and chest pain, including diltiazem (Cardizem) and verapamil (Calan, Verelan, Covera-HS)
  • The antipsychotic drug haloperidol (Haldol)

What is Anksilon (Buspar)? How does it work (mechanism of action)?

Anksilon is a medication that is used for the treatment of anxiety. Its mechanism of action is not clearly understood but may involve effects on neurotransmitters, chemicals that nerves use to communicate with one another. Serotonin and dopamine are two of these neurotransmitters. Anksilon may work by stimulating serotonin type 1A receptors on nerves, thereby altering the chemical messages that nerves receive. It also has minor effects on dopamine receptors but this does not contribute much to its action. Unlike medications for anxiety of the benzodiazepine class, for example, diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), and clonazepam (Klonopin), Anksilon does not cause sedation.

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