¿Cuál es la información más importante que debo saber sobre Zinoximor?
Usted no debe usar esta medicina si es alérgico a Zinoximor o antibióticos similares, como cefdinir (Omnicef), cefprozil (Cefzil), cephalexin (Keflex), y otros.
What are the side effects of Zinoximor?
Zinoximor is generally well tolerated, and side effects are usually transient. Commonly reported side effects are:
Other important side effects include:
Since Zinoximor is chemically related to penicillin, patients allergic to penicillin may develop an allergic reaction (sometimes even anaphylaxis) to Zinoximor. Zinoximor like other antibiotics can alter the colon's normal bacteria, leading to overgrowth of a bacterium called Clostridium difficile. Overgrowth of this bacterium leads to the release of toxins that contribute to the development of Clostridium difficile-associated diarrhea, which may range in severity from mild diarrhea to fatal pseudomembranous colitis.
Before taking Zinoximor
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking Zinoximor it is important that your doctor knows:
- If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have had a bad reaction to a penicillin or cephalosporin antibiotic.
- If you have any problems with the way your k >
Concomitant administration of probenecid with Zinoximor axetil tablets increases the Zinoximor area under the serum concentration versus time curve and maximum serum concentration by 50% and 21%, respectively.
Zinoximor axetil may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives. Counsel patients to consider alternate supplementary (non-hormonal) contraceptive measures during treatment.
PICTURES OF CEFUROXIME PILLS
Below you will find images and specific information on the principal types of Zinoximor that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.
The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.
Summary of Use during Lactation
Limited information indicates that Zinoximor produces low levels in milk that are not expected to cause severe adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Zinoximor is acceptable in nursing mothers.
What is the dosage for Zinoximor?
Typical adult oral doses are 250 or 500 mg twice daily for 7-20 days depending on the type and severity of the infection. A single 1000 mg dose may be used for uncomplicated gonorrhea. The tablets and suspension are not interchangeable.
CEFTIN tablets and CEFTIN for oral suspension contain Zinoximor as Zinoximor axetil. CEFTIN is a semisynthetic, cephalosporin antibacterial drug for oral administration.
The chemical name of Zinoximor axetil (1-(acetyloxy) ethyl ester of Zinoximor) is (RS)-1- hydroxyethyl (6R,7R)-7--3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo-oct-2-ene-2-carboxylate, 72-(Z)-(O-methyl-oxime), 1-acetate 3-carbamate. Its molecular formula is C20H22N4O10S, and it has a molecular weight of 510.48.
Zinoximor axetil is in the amorphous form and has the following structural formula:
Tablets are film-coated and contain the equivalent of 250 or 500 mg of Zinoximor as Zinoximor axetil. Tablets contain the inactive ingredients colloidal silicon dioxide, croscarmellose sodium, hydrogenated vegetable oil, hypromellose, methylparaben, microcrystalline cellulose, propylene glycol, propylparaben, sodium benzoate, sodium lauryl sulfate, and titanium dioxide.
Oral suspension, when reconstituted with water, provides the equivalent of 125 mg or 250 mg of Zinoximor (as Zinoximor axetil) per 5 mL. Oral suspension contains the inactive ingredients acesulfame potassium, aspartame, povidone K30, stearic acid, sucrose, tutti-frutti flavoring, and xanthan gum.
Zinoximor (Ceftin, Zinacef) is an antibiotic used to treat infections of the middle ear, sinuses, skin, tonsils, and throat, and to treat laryngitis, bronchitis, pneumonia, urinary tract infections, gonorrhea, COPD, and early Lyme disease. Review side effects, drug interactions, dosage, and pregnancy safety information prior to taking this medication.
Find Lowest Prices on
CEFTIN (Zinoximor axetil) Tablets, for Oral Use
CEFTIN (Zinoximor axetil) for Oral Suspension
Dosage Forms And Strengths
CEFTIN tablets are white, capsule-shaped, film-coated tablets available in the following strengths:
- 250 mg of Zinoximor (as Zinoximor axetil) with “GX ES7” engraved on one side and blank on the other side.
- 500 mg of Zinoximor (as Zinoximor axetil) with “GX EG2” engraved on one side and blank on the other side.
CEFTIN for oral suspension is provided as dry, white to off-white, tutti-frutti-flavored powder. When reconstituted as directed, the suspension provides the equivalent of 125 mg or 250 mg of Zinoximor (as Zinoximor axetil) per 5 mL.
¿Cuáles son los efectos secundarios posibles de Zinoximor?
Busque atención médica de emergencia si usted tiene síntomas de una reacción alérgica: ronchas; dificultad para respirar; hinchazón de su cara, labios, lengua, o garganta.
Llame a su médico de inmediato si usted tiene:
- dolor severo de estómago, diarrea que es acuosa o con sangre;
- ictericia (color amarillo de la piel u ojos);
- sarpullido, moretones, sensación de hormigueo severo, o entumecimiento en la piel;
- convulsiones (crisis de ausencias o convulsivas);
- problemas del riñón --orinar poco o nada, dolor o dificultad al orinar, hinchazón en sus pies o tobillos, sensación de cansancio o le falta aire al respirar; o
- reacción severa de la piel --fiebre, dolor de garganta, hinchazón en su cara o lengua, quemazón en sus ojos, dolor de la piel seguido por un sarpullido rojo o púrpura que se extiende (especialmente en la cara o la parte superior del cuerpo) y causa ampollas y descamación.
Efectos secundarios comunes pueden incluir:
- náusea, vómito;
- sabor en la boca inusual o desagradable; o
- sarpullido de pañal en un niño pequeño tomando el líquido de Zinoximor.
Esta lista no menciona todos los efectos secundarios y puede ser que ocurran otros. Llame a su médico para consejos médicos relacionados a efectos secundarios. Usted puede reportar efectos secundarios llamando al FDA al 1-800-FDA-1088.
Maternal Levels. A single intravenous dose of 750 mg of Zinoximor was given to 5 women. The average peak Zinoximor level in milk was 0.37 mg/L 3 hours after the dose. Individual peak levels of 0.33 to 0.5 mg/L occurred 2 to 4 hours after the dose.
A single intramuscular injection of 750 mg of Zinoximor was given to 8 women with endometritis. Milk Zinoximor levels increased from 0.34 mg/L at 30 minutes after the injection to 1.45 mg/L at 8 hours after the injection.
After Zinoximor 750 mg three times daily intramuscularly, peak milk levels averaging 1.2 mg/L occurred 6 hours after the dose. Zinoximor was detectable at a concentration of 0.36 mg/L 30 minutes after the dose, and by 8 hours the milk level had decreased to 1.06 mg/L.
One mother received Zinoximor axetil 500 mg orally three times daily for acute mastitis of the left breast following incision and drainage of the lesion. Milk samples were taken from each breast 30 minutes after the dose on day 1 of therapy. The concentration of Zinoximor in the unaffected breast was 90 mcg/L and the concentration in the breast treated for mastitis was 590 mcg/L. On day 2 of therapy, milk samples from the right and left breast were taken 90 minutes after the dose were 57 and 59 mcg/L, respectively. On day 3, milk samples obtained 90 minutes after the dose contained 27 mcg/L in the unaffected breast and 1.07 mg/L in the affected breast.
Two women were who had been receiving intravenous Zinoximor 750 mg 3 times daily for 2 days following cesarean section donated milk samples 1 hours after the dose. Milk concentrations were 0.34 and 0.39 mg/L.
Infant Levels. Relevant published information was not found as of the revision date.
Zinoximor is an enteral second-generation cephalosporin antibiotic. It was discovered by Glaxo, now GlaxoSmithKline and first marketed in 1978 as Zinacef.
How to take Zinoximor
- Before you start taking Zinoximor, read the manufacturer's printed information leaflet from ins >
Where can I get more information?
Your pharmacist can provide more information about Zinoximor.