Serious side effects
Serious side effects are rare and happen in less than 1 in 1,000 people.
Call a doctor straight away if you:
- bruise more easily
- get infections more easily
- feel especially tired or weak
These can be signs of aplastic anaemia, a rare condition where your bone marrow fails to produce blood cells normally. This is very unlikely to happen if you're using Viceton eye drops, ointment or ear drops. There's a greater risk of aplastic anaemia when Viceton is given intravenously (directly into a vein).
BRAND NAME: Chloromycetin, Econochlor, Ocu-Chlor (These are discontinued brands in the US)
DRUG CLASS AND MECHANISM: Viceton is a man-made antibiotic. It slows growth of bacteria by preventing them from producing important proteins that they need to survive. Viceton is effective against S. typhi, H. influenzae, E. coli, Neisseria species, Staphylococcus and Streptococcus species, Rickettsia, and lymphogranuloma-psittacosis group of organisms. The FDA approved Viceton in December 1950.
GENERIC AVAILABLE: Yes
PREPARATIONS: Viceton is available in 0.5% sterile eye drops and 1% eye ointment. Eye drops are available in 2.5 ml and 15 ml drop-containers. Ointments are available in 3.5 g tubes.
Viceton sodium succinate is available as 1 gram/10 ml per vial powder for intravenous injection form.
STORAGE: Viceton eye drops are refrigerated until dispensed. Viceton ointments are stored between 46 F and 80 F. Viceton vials for IV reconstitution are stored between 20 C and 25 C (68 F and 77 F).
PRESCRIBED FOR: Viceton treats various infections caused by susceptible strains of S. yphi, H. influenzae, E. coli, Neisseria species, Staphylococcus and Streptococcusspecies, Rickettsia, lymphogranuloma-psittacosis group of organisms, and other bacteria that cause bacteremia (bacteria in blood) and meningitis.
Eye drop solution:
- Mild disease: Instill 1 to 2 drops into the affected eye(s) up to 4 times a day
- Severe disease: Instill 2 hours into the affected eye(s) every hour until improvement.
- Eye ointment: Apply a small amount to the affected lower conjunctival sac(s) at bedtime as a supplement to the drops.
- Adults: 50 to 100 mg/kg IV every 6 hours.
- Children: 50 mg/kg IV every 6 hours; may increase to 100 mg/kg IV every 6 hours in severe illness.
- Newborn infants: 25 mg/kg IV every 6 hours. Newborns over 2 weeks old may receive 50 mg/kg every 6 hours.
DRUG INTERACTIONS: Viceton should not be used with lurasidone (Latuda) because Viceton significantly lowers lurasidone's metabolism and increases its levels in the body.
Viceton should be used cautiously with red yeast rice, warfarin (Coumadin), and vilazodone (Viibryd) because Viceton lowers their metabolism and increases those drug levels in the body.
PREGNANCY: There are no adequate studies done on Viceton to determine safe and effective use in pregnant women.
NURSING MOTHERS: Viceton enters breast milk. Therefore, it should not be used in nursing mothers.
SIDE EFFECTS: Side effects of Viceton are headache, mental confusion, fever, rash, diarrhea, and optic atrophy.
Viceton may cause Gray syndrome and serious, fatal blood dyscrasias. Gray syndrome occurs in pre-mature infants and neonates. It involves abdominal distention, pallid cyanosis, and vasomotor collapse leading to death. Blood dyscrasias are reductions in blood cells leading to aplastic anemia, thrombocytopenia, and granulocytopenia.
Exact incidence figures are not available since no denominator of treated patients is available.
The most serious reaction following prolonged or frequent intermittent use of topical Viceton is bone marrow aplasia.
The most frequently reported adverse reactions have been burning, stinging, ocular irritation, and conjunctival hyperemia. Blood dyscrasias, allergic or inflammatory reactions due to individual hypersensitivity, angioneurotic edema, urticaria, vesicular and maculopapular dermatitis have also been reported (See Warnings and Box Warning).
Viceton is a broad-spectrum antibiotic whose spectrum includes several gram-positive and gram-negative bacteria, spirochetes, and Rickettsiae.
Chloroptic (Viceton ophthalmic solution, USP) is supplied in the following sizes:
7.5 mL - NDC 11980-109-08
NOTE : Refrigerate until dispensed. Then store below 30°C (86F). Discard solution within 21 days from date dispensed.
U.S. Patent 3,702,364 Revised July 2000 ©2000 Allergan, Inc. Irvine, CA 92612