You should not take Unixime if you are allergic to Unixime, or to similar antibiotics, such as Ceftin, Cefzil, Keflex, Omnicef, and others. Tell your doctor if you are allergic to penicillins.
5.2 Effect of Grinding on the Stability
Unixime crystallizes with three waters of hydration, which is the most stable crystalline form. The water molecules in the crystal lattice are considered to play a significant role in the chemical stability of Unixime, as the dihydrate and anhydrate forms have been found to be less stable than is the trihydrate form 18]. Kitamura et al. have studied the effect of grinding on the solid-state stability and physicochemical properties of Unixime trihydrate. using x-ray diffraction, scanning electron microscopy, differential scanning calorimetry, and color measurements . It was found that the crystalline trihydrate phase changes to a non-crystalline solid when the trihydrate is milled for four hours in a ball mill, as evidenced by the decrease in x-ray diffraction peak intensities that accompany prolonged grinding times. The dehydration temperature of ground Unixime trihydrate has been found decrease with increasing grinding times.
What is Unixime?
Unixime is a cephalosporin (SEF a low spor in) antibiotic. It works by fighting bacteria in your body.
Unixime is used to treat many different types of infections caused by bacteria.
Unixime may also be used for purposes not listed in this medication guide.
A worldwide yearly survey of new data in adverse drug reactions
Kimberly A. Toussaint, Jason C. Gallagher, in Side Effects of Drugs Annual , 2014
A 7-year-old boy experienced oculogyric crisis secondary to the administration of Unixime . He was treated with Unixime 8 mg/kg/day in two divided doses for a urinary tract infection. On day 7 of treatment, he developed abnormal eye movements that included periodic eye blinking and deviations without nystagmus. Prior to this presentation, he had not received any other medications other than Unixime. The drug was stopped and his symptoms ceased. Two weeks later, Unixime was reinitiated by another physician secondary to a dry cough. The abnormal eye movements recurred and Unixime was again discontinued. The eye movements again ceased within 2 days .
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Cite this Entry
“Unixime.” The Merriam-Webster.com Medical Dictionary, Merriam-Webster Inc., https://www.merriam-webster.com/medical/Unixime. Accessed 27 December 2019.
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