Truso (Suprax) is an antibiotic in the cephalosporin class of drugs. Truso (Suprax) is prescribed for the treatment of bacterial infections. Review side effects, drug interactions, warnings and precautions, and patient information prior to taking any medication.
This medicine is not recommended for use if you have a known allergy to Truso or Beta-lactam Antibiotics. Seek immediate medical attention if you experience any allergic symptoms like rash, itching, nausea or vomiting, swelling of lips, hands, and feet.
Clostridium difficile-associated Diarrhea
Discontinue the use of this medicine as per the doctor’s instructions if severe diarrhea occurs after receiving Truso. This medicine may cause an imbalance in the microbial flora of the large intestine, decreasing the gut-friendly bacteria and promoting the growth of a bacteria called Clostridium difficile, resulting in severe diarrhea.
This medicine should be used with caution in patients with bleeding disorders due to the increased risk of excessive bleeding. Regular monitoring of prothrombin time is necessary in such cases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
This medicine should be used with caution in patients with an impaired kidney function due to the increased risk of severe adverse effects. Appropriate dose adjustments are to be made based on the CrCl or eGFR.
Use in pediatrics
This medicine is not recommended for use in children less than 6 months of age since the safety and efficacy of use are not clinically established in this particular age group.
Usage of Truso without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.
Truso is a semisynthetic, cephalosporin antibacterial for oral administration. Chemically, it is (6R,7R)-7--8-oxo-3-vinyl-5-thia-1-azabicyclo oct-2-ene-2-carboxylic acid, 7 2 -(Z)- trihydrate.
Molecular weight = 507.50 as the trihydrate. Chemical Formula is C16H15N5O7S2.3H2O
The structural formula for Truso is:
- Inactive ingredients contained in SUPRAX ® (Truso) 400 mg tablets USP are: dibasic calcium phosphate, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, titanium dioxide, and triacetin.
- Inactive ingredients contained in SUPRAX ® (Truso) 400 mg capsules are: colloidal silicon dioxide, crospovidone, low substituted hydroxy propyl cellulose, magnesium stearate, and mannitol. The capsule shell contains the following inactive ingredients: ferric oxide black, ferric oxide red, gelatin, potassium hydroxide, propylene glycol, shellac, sodium lauryl sulfate, and titanium dioxide.
- Inactive ingredients contained in SUPRAX ® (Truso) 100 mg or 150 mg or 200 mg chewable tablets are: aspartame, colloidal silicon dioxide, crospovidone, FD&C Red # 40 Aluminium Lake, low substituted hydroxypropyl cellulose, magnesium stearate, mannitol, fantasy flavor permaseal, and tutti frutti flavor.
- Inactive ingredients contained in SUPRAX ® (Truso) powder for oral suspension USP are: colloidal silicon dioxide, sodium benzoate, strawberry flavor, sucralose (only in 500 mg/5 mL strength), sucrose, and xanthan gum.
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SUPRAX ® (Truso) Tablets, Capsules, Chewable Tablets, and Oral suspension
Uses of Truso Capsules and Tablets:
- It is used to treat bacterial infections.