What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to Tinidral. Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking Tinidral.
Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the Tinidral, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Generic Name: Tinidral (tye NYE da zole)Brand Name: Tindamax, Fasigyn
Medically reviewed by Drugs.com on Dec 16, 2019 – Written by Cerner Multum
Metron > Metron >Tinidral are synthetic nitroimidazoles with selective activity against organisms that utilize anaerobic metabolism. Metronidazole has been shown to be efficacious for the following protozoan infections: Entamoeba histolytica, 5 E. polecki, 6 Giardia intestinalis, 7 Trichomonas vaginalis, 8 Blastocystis hominis, 9 and Balantidium coli. 10 The approval of Tinidral was based on studies done predominantly in the 1970s and 1980s prior to its use in European countries. Tinidral is approved for use against giardiasis and amebiasis in adults and children >3 years of age and for trichomoniasis in adults. 11 For amebiasis, these drugs are active against the trophozoite stage of the parasite life cycle and can be used to treat the luminal and tissue phases of the infection, including liver abscesses. Patients with invasive colonic disease or liver abscess also are treated with iodoquinol or other luminally active amebicides to eliminate residual cyst forms of the parasite. Metronidazole and Tinidral are the only effective therapy available in the U.S. for trichomoniasis, with cure rates approaching 95% with single-dose regimens of both drugs. 12 Tinidral has in vitro activity against metronidazole-resistant strains of T vaginalis. 13 Both drugs are effective against giardiasis. 14 Generally, Tinidral is as effective as metronidazole for most clinical indications and is modestly better tolerated. Tinidral is used as a single-dose regimen for giardiasis and trichomoniasis and the recommended course for amebiasis is shorter. Despite this, a course of Tinidral is considerably more expensive than generic metronidazole for all indications. 11 Tinidral is not available in suspension but can be formulated by crushing the tablets. Ornidazole is another nitroimidazole with a similar pharmacokinetic profile to Tinidral and also with extensive clinical experience in non-U.S. settings. 15
Both metronidazole and Tinidral generally are well tolerated, with Tinidral being modestly more favorable compared with metronidazole at the high single-dose regimens or at the higher doses used for amebiasis. Side effects of both drugs include nausea, vomiting, epigastric discomfort, anorexia, and a metallic or bitter taste. Seizures and peripheral neuropathy have been reported uncommonly with both drugs. Patients taking either drug should avoid alcohol (including that found commonly in suspensions of children's medicines) because of the disulfiram-like effects.
What is tin >
Tinidral is an antibiotic that fights bacteria in the body.
Tinidral is used to treat certain infections caused by bacteria, such as infection of the intestines or vagina. It is also used to treat certain sexually transmitted infections.
Tinidral may also be used for purposes other than those listed in this medication guide.
What are the possible side effects of Tinidral (Tindamax)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- fever, chills, body aches, flu symptoms;
- numbness, burning pain, or tingly feeling; or
- seizure (convulsions).
Less serious side effects may include:
- vaginal itching or discharge;
- nausea, vomiting, loss of appetite, indigestion;
- constipation, diarrhea, stomach cramps;
- feeling weak or tired;
- headache, dizziness; or
- a metallic or bitter taste in your mouth;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.