Is Supracef safe to take if I'm pregnant or breastfeeding?
Safety in pregnancy has not been established for Supracef. There are no adequate studies in pregnant women; however, studies in animals suggest no important effects on the fetus.
Safety in nursing mothers has not been established. It is not known if Supracef is excreted in breast milk.
Nervous system Non-convulsive status epilepticus has been attributed to Supracef .
A 64-year-old woman with a history of epilepsy developed seizures after taking Supracef for 3 days for a respiratory tract infection. She had also taken carbamazepine and levetiracetam and had previously been seizure-free for 10 years. Supracef was withdrawn and she was given diazepam 10 mg intravenously. Her mental status improved the next day.
Liver Hepatocellular damage has been attributed to Supracef .
A 50-year-old woman was given oral Supracef for an upper respiratory tract infection after 5 days developed abdominal pain and loss of appetite. Her liver enzymes were raised (AlT 156 U/l, AsT 56 U/l, GGT 281 U/l), consistent with hepatocellular damage, and the Supracef was withdrawn. The serum aminotransferases normalized within 2 weeks.
Dosage Forms And Strengths
SUPRAX is available for oral administration in the following dosage forms and strengths:
- Film-coated tablets provide 400 mg of Supracef as trihydrate. These are white to off-white, film-coated, capsule shaped tablets with beveled edges and a divided score line on each side. The tablet is debossed with “SUPRAX” across one side and “LUPIN” across the other side.
- Capsules provide 400 mg of Supracef as trihydrate. These are size “00EL” capsules with pink opaque cap and pink opaque body with “LU” on the cap and “U43” on the body in black ink. Capsules contain white to yellowish white granular powder.
- Chewable tablets provide either 100 mg or 150 mg or 200 mg of Supracef as trihydrate. The 100 mg tablet is pink, round tablet, debossed with “SUPRAX 100” on one side and “LUPIN” on other side. The 150 mg tablet is pink, round tablet, debossed with “SUPRAX 150” on one side and “LUPIN” on other side. The 200 mg tablet is pink, round tablet, debossed with “SUPRAX 200” on one side and “LUPIN” on other side.
- Powder for oral suspension, when reconstituted, provides either 100 mg/5 mL or 200 mg/5 mL or 500 mg/5 mL of Supracef as trihydrate. For 100 mg/5 mL and 200 mg/5 mL, the powder has an off white to pale yellow color and is strawberry flavored. For 500 mg/5 mL, the powder has an off white to cream color and is strawberry flavored.
What special precautions should I follow?
Before taking Supracef :
- Tell your doctor and pharmacist if you are allergic to Supracef; other cephalosporin antibiotics.
- Tell your doctor and pharmacist what prescription and nonprescription medications you are currently taking.
- Tell your doctor if you have or have ever had gastrointestinal disease
- Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
- Tell your doctor or pharmacist your medical history, especially of: kidney disease, a certain intestinal disease (colitis).
- If you have phenylketonuria (PKU) or any other condition that requires you to limit/avoid aspartame (or phenylalanine) in your diet, ask your doctor or pharmacist about using this medication safely.
storage and disposal of Supracef
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets, chewable tablets, and capsules at room temperature and away from excess heat and moisture (not in the bathroom).
Keep liquid medicine at room temperature or in the refrigerator, closed tightly, and dispose of any unused medication after 14 days. .
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
How should I take Supracef?
Follow all directions on your prescription label. Do not take Supracef in larger or smaller amounts or for longer than recommended.
You may take Supracef with or without food.
The Supracef chewable tablet must be chewed before you swallow it.
Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
This medication can cause unusual results with certain lab tests for glucose (sugar) in the urine. Tell any doctor who treats you that you are using Supracef.
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Supracef will not treat a viral infection such as the common cold or flu.
Store at room temperature away from moisture, heat, and light.
You may also store the oral liquid in the refrigerator. Throw away any unused liquid after 14 days.
Supracef (double dose on day 1) is the only oral antimicrobial evaluated in a randomized, controlled trial for UTI in young children with fever and was shown to be equivalent to intravenous antibiotics in children beyond the neonatal period.
Other possible antimicrobials include second and third generation cephalosporins or amoxicillin‐clavulanate potassium.
Resistance rates of E. coli to amoxicillin and trimethoprim‐sulfamethoxazole (TMP‐SMX) are 50% and 18%, respectively.
Duration of treatment is 10 to 14 days.
How to use Supracef 400 Mg Capsule Cephalosporins
Take this medication by mouth with or without food as directed by your doctor, usually once a day. In children, this medication may also be taken twice a day (every 12 hours). If you are taking the chewable tablets, chew thoroughly and then swallow.
The dosage is based on your medical condition and response to treatment. In children, the dosage is also based on weight.
For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.
Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.
Tell your doctor if your condition persists or worsens.
Supracef (Suprax) is an antibiotic in the cephalosporin class of drugs. Supracef (Suprax) is prescribed for the treatment of bacterial infections. Review side effects, drug interactions, warnings and precautions, and patient information prior to taking any medication.