Soxime tablets

Soxime

  • Active Ingredient: Cefuroxime
  • 500 mg, 250 mg
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What is Soxime?

The active ingredient of Soxime brand is cefuroxime. Cefuroxime is a cephalosporin (SEF a low spor in) antibiotic. It works by fighting bacteria in your body.

Used for

Soxime is used to treat diseases such as: Bacterial Infection, Bladder Infection, Bone infection, Bronchitis, Epiglottitis, Gonococcal Infection, Disseminated, Gonococcal Infection, Uncomplicated, Impetigo, Joint Infection, Kidney Infections, Lyme Disease, Meningitis, Otitis Media, Peritonitis, Pneumonia, Sepsis, Sinusitis, Skin and Structure Infection, Skin or Soft Tissue Infection, Strep Throat, Surgical Prophylaxis, Tonsillitis/Pharyngitis, Upper Respiratory Tract Infection, Urinary Tract Infection, Wound Infection.

Side Effect

Possible side effects of Soxime include: belching; pain during sexual intercourse; Chills; itching of the vagina or genital area; general feeling of tiredness or weakness.

How to Buy Soxime tablets online?

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What should I discuss with my healthcare prov >

Do not take this medicine if you are allergic to Soxime, or to other cephalosporin antibiotics, such as:

  • cefaclor (Raniclor);
  • cefadroxil (Duricef);
  • cefazolin (Ancef);
  • cefdinir (Omnicef);
  • cefditoren (Spectracef);
  • cefpodoxime (Vantin);
  • cefprozil (Cefzil);
  • ceftibuten (Cedax);
  • cephalexin (Keflex); or
  • cephradine (Velosef).

To make sure Soxime is safe for you, tell your doctor if you have:

  • an allergy to penicillin;
  • kidney disease;
  • liver disease;
  • a history of intestinal problems, such as colitis;
  • diabetes; or
  • if you are malnourished.

The liquid form may contain phenylalanine. Talk to your doctor before using this form of Soxime if you have phenylketonuria (PKU).

This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Soxime can make birth control pills less effective. Ask your doctor about using a non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

Soxime can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Soxime is not approved for use by anyone younger than 3 months old.

Getting the most from your treatment

  • Some people develop thrush (redness and itching in the mouth or vagina) after taking a course of antibiotics. If you think you have thrush speak with your doctor or pharmacist for advice.
  • If you are using oral combined hormonal contraception (the 'pill'), additional contraceptive precautions such as condoms are recommended for a time if you have vomiting or diarrhoea which lasts for more than 24 hours. If you need further advice about this, speak with your doctor or pharmacist.
  • If you are having an operation or any other medical treatment, tell the person carrying out the treatment that you are taking an antibiotic. This is because Soxime may interfere with the results of some tests to check for sugar in your urine.
  • Soxime may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this antibiotic.

Important: if you develop an itchy rash, or a swollen face or mouth, or have difficulty breathing, these can be signs that you are allergic to the antibiotic. Do not take any more Soxime and speak with your doctor or go to your local accident and emergency department straightaway.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist for further advice.

How to take Soxime

  • Before you start taking Soxime, read the manufacturer's printed information leaflet from ins >

¿Cuál es la información más importante que debo saber sobre Soxime?

Usted no debe usar esta medicina si es alérgico a Soxime o antibióticos similares, como cefdinir (Omnicef), cefprozil (Cefzil), cephalexin (Keflex), y otros.

Soxime is a broad-spectrum antibiotic, which means that it is active against a wide variety of bacteria. It is used to treat bacterial infections such as urinary tract infections, skin infections, chest infections, ear infections and sinusitis. It is also given before some surgical operations, to prevent an infection from occurring. Soxime treats an infection by killing the bacteria that are causing it.

Pregnancy

Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, CEFTIN should be used during pregnancy only if clearly needed.

Reproduction studies have been performed in mice at doses up to 3,200 mg/kg/day (14 times the recommended maximum human dose based on body surface area) and in rats at doses up to 1,000 mg/kg/day (9 times the recommended maximum human dose based on body surface area) and have revealed no evidence of impaired fertility or harm to the fetus due to Soxime axetil.

Carcinogenesis, Mutagenesis, Impairment Of Fertility

Although lifetime studies in animals have not been performed to evaluate carcinogenic potential, no mutagenic activity was found for Soxime axetil in a battery of bacterial mutation tests. Positive results were obtained in an in vitro chromosome aberration assay; however, negative results were found in an in vivo micronucleus test at doses up to 1.5 g/kg. Reproduction studies in rats at doses up to 1,000 mg/kg/day (9 times the recommended maximum human dose based on body surface area) have revealed no impairment of fertility.

¿Qué otras drogas afectarán a Soxime?

Dígale a su médico todas las medicinas que usa, y cualquiera que comience o deje de usar, especialmente:

  • probenecid (Benemid);
  • un anticoagulante como warfarin (Coumadin, Jantoven); o
  • un diurético o "pastilla para eliminar el agua."

Esta lista no está completa. Otras drogas pueden interactuar con Soxime, incluyendo medicinas que se obtienen con o sin receta, vitaminas, y productos herbarios. No todas las interacciones posibles aparecen en esta guía del medicamento.

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CEFTIN (Soxime axetil) Tablets, for Oral Use

CEFTIN (Soxime axetil) for Oral Suspension

Two adequate and well-controlled trials were performed in subjects with early Lyme disease. All subjects presented with physician-documented erythema migrans, with or without systemic manifestations of infection. Subjects were assessed at 1 month posttreatment for success in treating early Lyme disease (Part I) and at 1 year posttreatment for success in preventing the progression to the sequelae of late Lyme disease (Part II).

A total of 355 adult subjects (181 treated with Soxime axetil and 174 treated with doxycycline) were randomized in the 2 trials, with diagnosis of early Lyme disease confirmed in 79% (281/355). The clinical diagnosis of early Lyme disease in these subjects was validated by 1) blinded expert reading of photographs, when available, of the pretreatment erythema migrans skin lesion, and 2) serologic confirmation (using enzyme-linked immunosorbent assay and immunoblot assay ) of the presence of antibodies specific to Borrelia burgdorferi, the etiologic agent of Lyme disease. The efficacy data in Table 13 are specific to this “validated” patient subset, while the safety data below reflect the entire patient population for the 2 trials. Clinical data for evaluable subjects in the “validated” patient subset are shown in Table 13.

Table 13: Clinical Effectiveness of CEFTIN Tablets Compared with Doxycycline in the Treatment of Early Lyme Disease

CEFTIN and doxycycline were effective in prevention of the development of sequelae of late Lyme disease.

While the incidence of drug-related gastrointestinal adverse reactions was similar in the 2 treatment groups (Soxime axetil - 13%; doxycycline - 11%), the incidence of drug-related diarrhea was higher in the Soxime axetil arm versus the doxycycline arm (11% versus 3%, respectively).

1. Clinical and Laboratory Standards Institute (CLSI). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically; Approved Standard - Tenth Edition. 2015. CLSI document M07-A10, Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA.

2. Clinical and Laboratory Standards Institute (CLSI). Methods for Antimicrobial Dilution and Disk Susceptibility Testing for Infrequently Isolated or Fastidious Bacteria: Approved Guidelines - Second Edition. 2010. CLSI document M45-A2, Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA.

3. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing; Twenty-fifth Informational Supplement. 2015. CLSI document M100- S25, Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA.

4. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Disk Diffusion Susceptibility Tests; Approved Standard - Twelfth Edition. 2015. CLSI document M02-A12, Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA.

If you have a bacterial infection, you may benefit from Soxime axetil. Uses of this medication include treatment of tonsillitis, strep throat, ear infections, skin infections, and bronchitis, to name a few. This prescription medication works by preventing the bacteria from forming cell walls. It is approved for use in both adults and children (as young as three months old).

Our free DiscountRx savings card can help you and your family save money on your prescriptions. This card is accepted at all major chain pharmacies, nationwide. Enter your name and email address to receive your free savings card.

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Probenecid

Concomitant administration of probenecid with Soxime axetil tablets increases serum concentrations of Soxime . Coadministration of probenecid with Soxime axetil is not recommended.


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