Qinosyn tablets

Qinosyn

  • Active Ingredient: Ciprofloxacin
  • 1000 mg, 750 mg, 500 mg, 250 mg
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What is Qinosyn?

The active ingredient of Qinosyn brand is ciprofloxacin. Ciprofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Ciprofloxacin is used to treat different types of bacterial infections. Ciprofloxacin is also used to treat people who have been exposed to anthrax or certain types of plague. Ciprofloxacin film-coated Tablets are available in 250 mg, 500 mg and 750 mg (Ciprofloxacin equivalent) strengths. Ciprofloxacin tablets USP are white to slightly yellowish. The inactive ingredients are pregelatinized starch, microcrystalline cellulose, colloidal silicon dioxide, crospovidone, magnesium stearate, hypromellose, titanium dioxide, polyethylene glycol, and purified water.

Used for

Qinosyn is used to treat diseases such as: Anthrax, Anthrax Prophylaxis, Bacteremia, Bacterial Infection, Bladder Infection, Bone infection, Bronchiectasis, Bronchitis, Chancroid, Cholera, Crohn's Disease, Cutaneous Bacillus anthracis, Diverticulitis, Epididymitis, Sexually Transmitted, Febrile Neutropenia, Gonococcal Infection, Disseminated, Gonococcal Infection, Uncomplicated, Granuloma Inguinale, Infection Prophylaxis, Infectious Diarrhea, Intraabdominal Infection, Joint Infection, Kidney Infections, Meningococcal Meningitis Prophylaxis, Mycobacterium avium-intracellulare, Treatment, Nosocomial Pneumonia, Peritonitis, Plague, Plague Prophylaxis, Pneumonia, Pneumonia with Cystic Fibrosis, Pouchitis, Prostatitis, Rabbit Fever, Salmonella Enteric Fever, Salmonella Gastroenteritis, Shigellosis, Sinusitis, Skin and Structure Infection, Skin or Soft Tissue Infection, Surgical Prophylaxis, Traveler's Diarrhea, Tuberculosis, Active, Typhoid Fever, Urinary Tract Infection.

Side Effect

Possible side effects of Qinosyn include: unusual bleeding or bruising; difficulty with breathing, chewing, or talking; burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings; unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness; swollen, painful, or tender lymph glands in the neck, armpit, or groin; severe abdominal or stomach pain, cramping, or burning; nightmares.

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Rated Qinosyn (Cipro) for Cystitis Report

I was perscribed this for a UTI. An hour after taking it I developed severe and burning pain in my calves that eventually spread to my body. I couldn't stand for 2 days and could barely move for about a week. I'm still weak and exhausted and in pain and in its been a month now. All from ONE pill. This drug is horrible and I'm angry and upset that it was perscribed for something that could have been treated with a drug with far fewer and far less dangerous side effects.

Rated Qinosyn (Cipro) for Diverticulitis Report

I was prescribed Metronidazole AND Qinosyn 500mg each. Next time my diverticulitis flares up, I'm going on a garlic soup diet or something other than pharmaceuticals. Cause Damn. Side effects of taking both these drugs together. dizzy, diarrhea, stoned (but not fun), found out that Metronidazole is actually a carcinogen and Qinosyn destroys your tendons. Look it up. I'm only 2 days in on a 10 day prescription, which I'll cut to 5-7 days since I've seen that's been prescribed elsewhere. Just hoping there's no permanent damage done after taking these drugs.

What should I avoid while taking Qinosyn?

Do not take Qinosyn with dairy products such as milk or yogurt, or with calcium- fortified juice. You may eat or drink these products with your meals, but do not use them alone when taking Qinosyn. They could make the medication less effective.

Using caffeine while taking Qinosyn can increase the effects of the caffeine.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Qinosyn could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Tell your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Rated Qinosyn (Cipro) for Prostatitis Report

Development of a myarid of health issues afterwards. I was perfectly healthy prior. Years later and 1/2 million dollars in Medical Bills was diagnosed with Mitochondrial Myopathy. If you are one of the unlucky individuals who has a genetic predisposition of not being able to metabolize the drug probably be prepared for a living nightmare. FYI if you take the generic version Qinosyn under current law you will have no means of legal recourse under current Federal and 47 States.

Other uses for this medicine

In the event of biological warfare, Qinosyn may be used to treat and prevent dangerous illnesses that are deliberately spread such as tularemia and anthrax of the skin or mouth. Qinosyn is also sometimes used to treat cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease (type of lung infection), chancroid (genital sores caused by bacteria), granuloma inguinale (donovanosis; a sexually transmitted disease), and infections of the outer ear that spread to the bones of the face. Qinosyn may also be used to help treat tuberculosis and Crohn's disease (condition in which the immune system attacks the lining of the digestive tract causing pain, diarrhea, weight loss, and fever). Qinosyn is also sometimes used to prevent traveler's diarrhea in certain patients and to prevent infections in patients who have fever and are at high risk for infection because they have very few white blood cells, people who are having certain types of surgery, and those people in close contact with someone who is sick with meningitis. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Rated Qinosyn (Cipro) for Sinusitis Report

I took one pill 13 hours ago and now my left leg is one giant tendor cramp. Stopping the course after one pill. Hope it isn't permanent. Was mot warned by doctor of all the side effects that could happen and hopefully they don't rear their ugly heads after just one pill.

Adverse Laboratory Changes

Changes in laboratory parameters while on CIPRO are listed below:

Hepatic – Elevations of ALT (SGPT), AST (SGOT), alkaline phosphatase, LDH, serum bilirubin.

Hematologic – Eosinophilia, leukopenia, decreased blood platelets, elevated blood platelets, pancytopenia.

Renal – Elevations of serum creatinine, BUN, crystalluria, cylindruria, and hematuria have been reported.

Other changes occurring were: elevation of serum gammaglutamyl transferase, elevation of serum amylase, reduction in blood glucose, elevated uric acid, decrease in hemoglobin, anemia, bleeding diathesis, increase in blood monocytes, and leukocytosis.

Read the entire FDA prescribing information for Cipro (Qinosyn)

What other drugs will affect Qinosyn?

Before giving Qinosyn, tell your veterinarian if your pet is being given warfarin, theophylline, probenecid, insulin or oral diabetes medication such as Glipizide, an NSAID such as carprofen, Deramaxx or other, Phenytoin or cyclosporine modified. Drugs other than those listed may also interact with Qinosyn. Talk to your veterinarian or pharmacist before giving any prescription or over-the-counter medications.

Qinosyn Dosage

Your dose of Qinosyn will depend on the type of bacterial infection you have.

Qinosyn comes in regular and extended-release tablets and as a liquid.

Take regular tablets or the liquid twice a day (morning and evening) at about the same time each day, and take extended-release tablets once a day.

Swallow all tablets whole. Don't crush, split, or chew them.

Regular tablets come in 250, 500, and 750 milligrams (mg).

Some typical doses for common infections using regular tablets include:

  • Uncomplicated gonorrhea infection: 250 mg, single dose
  • Uncomplicated urinary tract infection: 250 mg every 12 hours for three days
  • Bacterial diarrhea: 500 mg every 12 hours for five to seven days
  • Acute sinusitis: 500 mg every 12 hours for 10 days
  • Severe pneumonia: 750 mg every 12 hours for seven to 14 days
  • Chronic bacterial prostatitis: 500 mg every 12 hours for 28 days
  • Moderate bone or joint infection: 500 mg every 12 hours for four to six weeks

Getting the most from your treatment

  • Remember to keep any routine appointments with your doctor. This is so your progress can be monitored.
  • Qinosyn may cause your skin to become more sensitive to sunlight than normal. Protect your skin by using a sunscreen, particularly if you are exposed to strong sunlight for a prolonged period of time. Do not use sunbeds.
  • If you buy any medicines, check with a pharmacist that they are safe to take with this antibiotic. In particular, do not take painkillers called non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, while you are taking Qinosyn.
  • Some people develop thrush (redness and itching in the mouth or vagina) after taking a course of antibiotics. If you think you have thrush, speak with your doctor or pharmacist for advice.
  • This antibiotic may stop the oral typhoid vaccine from working. If you are due to have any vaccinations, make sure the person treating you knows that you are taking this medicine.
  • Qinosyn may make you feel light-headed and impair your ability to concentrate. Make sure your reactions are normal before you drive and before you use tools or machines.
  • If you have diabetes, you may need to check your blood glucose levels more regularly, as Qinosyn can affect the levels of sugar in your blood.

Qinosyn is given to treat a bacterial infection. It is useful for treating infections such as chest infections, urine infections, prostatitis, infections of the digestive system, bone and joint infections, and some sexually transmitted infections. It works by killing the bacteria which are the cause of the infection.

Qinosyn (Cipro) is more effective than amoxicillin-clavulanate (Augmentin) as a treatment for bladder infections in women, even when the microbe is susceptible to the latter drug, according to a report in the Journal of the American Medical Association.

Currently, the standard treatment for bladder infections or cystitis is trimethoprim-sulfamethoxazole (Bactrim), but emerging resistance to this agent has led to greater use of “fluoroquinolone” drugs, such as Qinosyn. In an effort to maintain the usefulness of this drug class, however, there has been a push to use non-fluoroquinolone antibiotics.

Despite increasing use of amoxicillin-clavulanate for cystitis, few studies have assessed the effectiveness of this treatment, according to Dr. Thomas M. Hooton of Harborview Medical Center in Seattle, and colleagues.

To investigate, the researchers assessed cure rates in 370 women with cystitis who were randomly selected to receive a 3-day course of Qinosyn or amoxicillin-clavulanate.

Cure was achieved in 77 percent of Qinosyn-treated women compared with just 58 percent of amoxicillin-clavulanate-treated women. Moreover, even when the analysis was confined to women infected with bacteria susceptible to amoxicillin-clavulanate, Qinosyn still provided a higher cure rate.

The authors believe that Qinosyn may have worked better than amoxicillin-clavulanate because of eradication of E. coli bacteria in the vagina. At 2-week follow-up, 45 percent of women treated with amoxicillin-clavulanate had vaginal E. coli compared with just 10 percent of women treated with Qinosyn.

The results, the investigators conclude, suggest that amoxicillin-clavulanate should only be considered as a treatment for cystitis when “use of other first- and second-line antibiotics is not feasible.”

SOURCE: Journal of the American Medical Association, February 23, 2005.

¿Qué es Qinosyn?

Qinosyn es un antibiótico fluoroquinolona que combate la bacteria en su cuerpo. Qinosyn se usa para tratar varios tipos de infecciones bacterianas. Qinosyn se usa también para tratar personas que se han sido expuestas al ántrax o ciertos tipos de la plaga.

Los antibióticos fluoroquinolonas pueden causar efectos secundarios serios o incapacitantes. Qinosyn debe usarse solamente para infecciones que no se pueden tratar con un antibiótico más seguro.

Qinosyn puede también usarse para fines no mencionados en esta guía del medicamento.

What are the important side effects of Cipro (Qinosyn)?

Cipro and Cipro XR as well as other antibiotics in the fluoroquinolone class of antibiotics has been associated with tendonitis and even tendon rupture, particularly the Achilles tendon. Some doctors and other medical professionals recommend that their patients discontinue vigorous exercise while they are taking fluoroquinolone antibiotics.

Fluoroquinolones have neuromuscular blocking activity and can worsen muscle weakness in individuals with myasthenia gravis.

The most common side effects of Cipro, Cipro XR are:

Anaphylaxis, or shock, is a rare allergic reaction to this drug. This allergic reaction is a medical emergency and you are experiencing these symptoms seek medical immediately.

Symptoms of shock include:

  • Cardiovascular collapse
  • Facial or throat swelling
  • Shortness of breath
  • Hives
  • Itching

Other possible serious side effects of Cipro, Cipro XR include:

  • Peripheral neuropathy
  • toxic psychosis,
  • nervousness,
  • agitation,
  • insomnia,
  • anxiety,
  • nightmares,
  • paranoia,
  • dizziness,
  • tremors,
  • depression, and
  • hallucinations.
  • Hyperglycemia
  • Clostridiumdifficile-associated diarrhea (CDAD)
  • Abnormal heartbeats
  • Liver dysfunction
  • Stroke
  • Convulsions
  • Toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • Vasculitis
  • Allergic pneumonitis
  • Interstitial nephritis
  • Acute kidney failure
  • Hepatitis
  • Jaundice
  • Liver failure
  • Anemia
  • Leukopenia
  • Cardiac arrest
  • Respiratory failure
  • Other serious side effects and adverse events of Cipro, Cipro XR include:

    Cipro, Cipro XR should be used with caution in patients with central nervous system diseases such as seizures, because rare seizures have been reported in patients receiving Cipro, Cipro XR.

    Cipro, Cipro XR should be avoided in children and adolescents less than 18 years of age, as safe use in these patients has not been established.

    Many antibiotics, including Cipro, Cipro XR, can alter the normal bacteria in the colon and encourage overgrowth of a bacterium responsible for the development of inflammation of the colon, (C. difficile or pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting Cipro, Cipro XR (diarrhea, fever, abdominal pain, and possibly shock) should contact their doctor immediately.

    Qinosyn Overdose

    A large overdose of Qinosyn could cause kidney damage.

    In animal studies, very large doses of Qinosyn have caused reduced breathing, vomiting, and seizures.

    If an overdose occurs, call a poison control center at 1-800-222-1222.

    If you or someone else has any severe symptoms after an overdose, call 9-1-1.


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