Proderma capsules


  • Active Ingredient: Doxycycline
  • 200 mg, 100 mg
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What is Proderma?

The active ingredient of Proderma brand is doxycycline. Doxycycline is a tetracycline antibiotic that fights bacteria in the body.

Used for

Proderma is used to treat diseases such as: Acne, Actinomycosis, Amebiasis, Anthrax, Anthrax Prophylaxis, Bacterial Infection, Bartonellosis, Bronchiectasis, Bronchitis, Brucellosis, Bullous Pemphigoid, Cervicitis, Chancroid, Chlamydia Infection, Cholera, Cutaneous Bacillus anthracis, Ehrlichiosis, Enterocolitis, Epididymitis, Sexually Transmitted, Gastroenteritis, Gonococcal Infection, Uncomplicated, Granuloma Inguinale, Inclusion Conjunctivitis, Lyme Disease, Lyme Disease, Arthritis, Lyme Disease, Carditis, Lyme Disease, Erythema Chronicum Migrans, Lyme Disease, Neurologic, Lymphogranuloma Venereum, Malaria, Malaria Prevention, Melioidosis, Mycoplasma Pneumonia, Nongonococcal Urethritis, Ocular Rosacea, Ornithosis, Pelvic Inflammatory Disease, Pemphigoid, Pemphigus, Periodontitis, Plague, Pleural Effusion, Pneumonia, Proctitis, Prostatitis, Psittacosis, Q Fever, Rabbit Fever, Rheumatoid Arthritis, Rickettsial Infection, Rosacea, Skin or Soft Tissue Infection, STD Prophylaxis, Syphilis, Early, Syphilis, Latent, Tertiary Syphilis, Trachoma, Upper Respiratory Tract Infection, Urinary Tract Infection.

Side Effect

Possible side effects of Proderma include: clay-colored stools; dark urine; difficulty breathing; sores in the mouth; yellow eyes or skin.

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Proderma and Alcohol

It's possible to drink alcohol while taking Proderma, but use of alcohol may increase your risk of side effects, including stomach upset.

Talk with your doctor about the risks of combining alcohol and Proderma.

Proderma for Dogs and Cats

Proderma is often used to treat bacterial infections in dogs, cats, and other animals.

Proderma may be prescribed to treat several bacterial infections, such as leptospirosis, urinary tract infections (UTI), toxoplasmosis, erlichiosis, or mycoplasma.

It's also used to treat tick-borne diseases, including Lyme disease and Rocky Mountain spotted fever.

Because Proderma can cause severe side effects in dogs and cats (such as nausea and diarrhea), it should be used only under the care and direction of a veterinarian.

What if I take too much?

Accidentally taking an extra dose of Proderma is unlikely to harm you.

Speak to your pharmacist or doctor if you're worried or you take more than 1 extra dose.

Like all medicines, Proderma can cause side effects, although not everyone gets them.

3. Who can and can't take Proderma

Proderma can be taken by adults and children over 12 years old. Proderma is not usually recommended in pregnancy or when breastfeeding.

It isn't suitable for some people. To make sure this medicine is safe for you, tell your doctor if you have:

  • ever had an allergic reaction to Proderma or any other medicine in the past
  • kidney problems
  • liver problems
  • an inflamed food pipe (oesophagitis)
  • lupus, an autoimmune disease
  • myasthenia gravis, an illness that causes severe muscle wasting

How to take it

Always swallow your Proderma capsule whole and have it with a full glass of water (a medium sized glass - 200ml).

You can take this medicine with or without food. However you're less likely to feel sick if you have it with food.

It's important to take Proderma while you're in an upright position. You can be sitting, standing or walking. This will stop the medicine irritating your food pipe or stomach.

Q: I have a recurrent sinus infection and have been prescrived Proderma for 30 days. Does it take that long for the antibiotic to work?

A: When an antibiotic is started for an infection an improvement is usually seen within a few days. It is important to take your full course of prescribed antibiotic even if you are feeling better. It will take the full course for the antibiotic to fully kill off the bacteria. If an antibiotic is only taken for a few of the prescribed days, the bacteria may mutate themselves to become resistant to that antibiotic. If enough antibiotics are taken this way, a strain of bacteria could develop that is resistant to all available antibiotics and could not be treated. That is why it is so important to take your antibiotic until it is all gone, unless otherwise directed by your health care provider. Laura Cable, PharmD, BCPS

Q: Is Proderma different than Malarone?

A: Proderma is a tetracycline-type antibiotic used to treat bacterial infections (e.g., Rickettsial infections, sexually transmitted infections, respiratory tract infections, ophthalmic infections, Anthrax, adjunctive therapy in acute intestinal amebiasis and severe acne, and prophylaxis of malaria). The most common side effects reported with tetracyclines include anorexia, nausea, vomiting, diarrhea, rash, photosensitivity, urticaria, and hemolytic anemia. Malarone is a combination of atovaquone and proguanil. These medications are used to treat and prevent malaria. Malaria is caused by parasites and these drugs work to inhibit the growth to the parasites in the human body. Malarone is associated with headache, cough, abdominal pain, and vomiting, nausea, diarrhea, weakness and dizziness. Proderma should be taken with plenty of fluids to minimize stomach irritation. Proderma should not be taken with dairy products or high-fat foods. Malarone should be taken with food to minimize stomach upset. Michelle McDermott, RPh, PharmD

By Mary Elizabeth Dallas | Medically Reviewed by Niya Jones, MD, MPH

Latest Update: 2014-07-31 Copyright © 2014 Everyday Health Media, LLC

1. About Proderma

Proderma is an antibiotic.

It's used to treat infections such as chest infections, skin infections, rosacea, dental infections and sexually transmitted infections (STIs), as well as a lot of other rare infections.

It can also be used to prevent malaria if you're travelling abroad.

Proderma is available on prescription. It comes as capsules.

6. How to cope with s >

What to do about:

  • headaches - make sure you rest and drink plenty of fluids. Everyday painkillers, such as paracetamol and ibuprofen, are safe to take with Proderma.
  • feeling or being sick (nausea or vomitting) - stick to simple meals and do not eat rich or spicy food. It might help to take your Proderma after a meal or snack but avoid dairy products like milk, cheese and yoghurt. Dairy products can stop your body absorbing your medicine properly. If you are being sick, drink plenty of fluids, such as water or squash, to avoid dehydration. Signs of dehydration include peeing less than usual or having strong-smelling pee. Do not take any medicines to treat vomiting without speaking to a pharmacist or doctor.
  • sensitivity to sunlight - when you go outside, wear sunglasses and clothes that cover you up. Put sunscreen or sunblock on your skin - with a sun protection factor (SPF) of at least 15 (if you have fair skin, you may need a much higher number than this). Also use a sunscreen product for your lips. Do not use sunlamps or tanning beds. If you get sunburn, there are things you can do to treat your symptoms.

Outcome and Management

Recovery after withdrawal of Proderma is usually rapid, but in instances with severe cholestasis, can require 2 to 6 months. No case of acute liver failure has been reported due to Proderma, but rare instances of vanishing bile duct syndrome have been linked to its use. Cross sensitivity to hepatic injury between minocycline and Proderma has not been shown, but both can cause a short incubation period acute hepatitis with immunoallergic features, so that some degree of cross reactivity may occur.

8. Cautions with other medicines

There are some medicines that don't mix well with Proderma.

Tell your doctor if you're taking these medicines before you start taking Proderma:

  • indigestion remedies (antacids)
  • supplements which contain aluminium, bismuth, calcium, magnesium or zinc
  • stomach ulcer medicines that contain bismuth
  • iron supplements
  • other antibiotics
  • acne medicines which contain vitamin A, such as isotretinoin
  • a blood thinner called warfarin
  • medicines for epilepsy, such as phenytoin or carbamazepine
  • ciclosporin, a medicine to damp down your immune system

Typhoid vaccine given by mouth may not work properly if you're taking Proderma. If you need a typhoid vaccine while taking Proderma, your doctor or nurse will give it by injection.

9. Common questions

Proderma is from a group of medicines called tetracycline antibiotics. These antibiotics kill bacteria by stopping them from making the proteins that they need to survive.

For most infections, you should feel better within a few days.

It's very important that you keep taking Proderma until you finish your medicine. Do this even if you feel better. It will help stop the infection coming back.

If you have rosacea, Proderma works slowly to treat it. Your doctor will usually review you after 4 to 6 weeks to check how well the medicine is working.

If you are taking Proderma for any other infection, tell your doctor if you don't start feeling better after 3 days. Also tell them if, at any time, you start to feel worse.

If you are taking Proderma to prevent malaria, you will not feel any different. You should take Proderma as prescribed, and continue taking it for 4 weeks after leaving the area where there is malaria.

Some people get a fungal infection called thrush after taking a course of antibiotics like Proderma. Antibiotics kill the normal harmless bacteria that help to protect you against thrush.

If this happens to you, ask your pharmacist or doctor for advice.

Proderma does not affect any type of contraception, including the contraception pill and emergency contraception.

However, if Proderma makes you vomit or have severe diarrhoea (6 to 8 watery poos in 24 hours) for more than 24 hours, your combined pill may not protect you from pregnancy. Look on the pill packet to find out what to do.

There's no firm evidence to suggest that taking Proderma will reduce fertility in either men or women.

However, speak to a pharmacist or your doctor before taking it if you're trying to get pregnant.

Proderma can build up in growing bones and teeth by binding to calcium. This can stain teeth.

It only happens in growing bones and teeth. This is why Proderma is not given to children under 12 years old or to pregnant or breastfeeding women.

Yes, Proderma shouldn't affect you being able to drive or cycle.

Avoid drinking alcohol with Proderma. Alcohol can stop it working properly. Speak to your doctor or pharmacist if you have questions about this.

Do not take your medicine together with dairy products. This is because dairy foods like milk, cheese and yoghurt can stop your body from absorbing Proderma. You can have dairy products a few hours before or after your dose.

Avoid drinking alcohol with Proderma.

Yes, you can take Proderma if you are allergic to penicillin. They are 2 different types of antibiotic.

Proderma has been used successfully in hot countries for many years. The best way to protect yourself against a reaction to sunlight is to be careful with sun exposure.

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