Orixyl tablets


  • Active Ingredient: Amoxicillin
  • 500 mg, 250 mg
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What is Orixyl?

The active ingredient of Orixyl brand is amoxicillin. Amoxicillin is a penicillin antibiotic that fights bacteria. The Amoxicillin molecular formula is C16H19N3O5S•3H2O, and the molecular weight is 419.45. Capsules of Amoxicillin are intended for oral administration. Each capsule of Amoxicillin with blue cap and pink body, contains 250 mg or 500 mg Amoxicillin as the trihydrate. The body of the 250 mg capsule is imprinted with ‘A44’ in black ink. The body of the 500 mg capsule is imprinted with ‘A45’ in black ink. Inactive ingredients: microcrystalline cellulose, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin, magnesium stearate, titanium dioxide, and sodium lauryl sulfate. Meets USP Dissolution Test 2.

Used for

Orixyl is used to treat diseases such as: Actinomycosis, Anthrax Prophylaxis, Bacterial Endocarditis Prevention, Bacterial Infection, Bladder Infection, Bronchiectasis, Bronchitis, Chlamydia Infection, Cutaneous Bacillus anthracis, Dental Abscess, Helicobacter Pylori Infection, Lyme Disease, Arthritis, Lyme Disease, Carditis, Lyme Disease, Erythema Chronicum Migrans, Lyme Disease, Neurologic, Otitis Media, Pneumonia, Sinusitis, Skin or Soft Tissue Infection, Spleen Removal, Tonsillitis/Pharyngitis, Upper Respiratory Tract Infection, Urinary Tract Infection.

Side Effect

Possible side effects of Orixyl include: nosebleeds; joint or muscle pain; diarrhea; bloating; Bad, unusual, or unpleasant (after) taste; feeling of discomfort; tenderness; fast heartbeat.

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Orixyl Overdose

Though rare, it's possible to take an overdose of Orixyl.

If you or someone else takes too much medicine, call your local poison control center at 1-800-222-1222.

If the person collapses, stops breathing, or has any severe symptoms after an overdose, call 9-1-1.

Is Orixyl safe to take if I am pregnant or breastfeeding?

  • Penicillins are generally considered safe for use by pregnant women who are not allergic to penicillin.
  • Small amounts of Orixyl may be excreted in breast milk and may cause diarrhea or allergic responses in nursing infants. Orixyl is generally considered safe to use while breastfeeding. Orixyl is used to treat infections in the newborn.

Breathing problems

Breathing difficulty involves a sensation of difficult or uncomfortable breathing or a feeling of not getting enough air.

In some circumstances, a small degree of breathing difficulty may be normal. Severe nasal congestion is one example. Strenuous exercise, especially when you do not exercise regularly, is another example.

If you have difficulty breathing, you could be experiencing an allergic reaction to Orixyl.

If you’re experiencing mild breathing problems, you can try to ease breathing by doing the following:

  • Breathe through pursed lips, which slows down breathing and allows for deeper breaths.
  • Perform activities at a comfortable pace; avoid rushing.
  • Try not to hold your breath.
  • Sit in front of a fan.

If you are allergic to Orixyl or penicillin, inform your doctor so you can be prescribed another medication to prevent this reaction. If breathing becomes increasingly difficult, contact your doctor right away.

If you have swelling of your lips, face, mouth or throat, and difficulty breathing call 911 or go to the emergency room.

Orixyl Directions:

  • Orixyl is a broad-spectrum penicillin antibiotic available by prescription used to treat various infections caused by susceptible strains of bacteria.
  • Orixyl can be used to treat infections such as ear infections, urinary tract infections, and skin infections. Orixyl may also be used for purposes other than those listed.
  • Orixyl is available in tablet form in 100 mg and 400 mg strengths, and in capsule form in 250 mg and 500 mg strengths.

Contact your veterinarian immediately if your pet develops severe or bloody diarrhea. Give all of the Orixyl that is prescribed for your pet. Symptoms may begin to improve before the infection is completely treated.

Michael Stewart, Reviewed by Sid Dajani | Last edited 23 Apr 2019 | Certified by The Information Standard

Make sure you tell your doctor if you are allergic to penicillin. Orixyl is a type of penicillin - do not take it if you are allergic to penicillin.

Space your doses out evenly over the day and complete the full course of the antibiotic, even if you feel your infection has cleared up. You can take Orixyl either before or after food.

If you have an allergic reaction (such as any swelling around your mouth, any difficulties breathing or a red rash) contact a doctor for advice straightaway.

9. Common questions

Orixyl is a similar antibiotic to penicillin. It works by killing the bacteria that cause the infection.

For most infections, you should feel better within a few days.

It's very important that you keep taking Orixyl until your course is finished. Do this even if you feel better. It will help stop the infection coming back.

Tell your doctor if you don't start feeling better after taking Orixyl for 3 days. Also tell them if, at any time, you start to feel worse.

Some people get a fungal infection called thrush after taking a course of antibiotics like Orixyl. It happens because antibiotics kill the normal harmless bacteria that help to protect you against thrush.

Ask your pharmacist or doctor for advice if this happens to you.

Orixyl doesn't stop contraceptive pills working, including the combined pill or emergency contraception.

However, if Orixyl makes you vomit or have severe diarrhoea (6 to 8 watery poos in 24 hours) for more than 24 hours, your contraceptive pills may not protect you from pregnancy. Look on the pill packet to find out what to do.

There's no firm evidence to suggest that taking Orixyl will reduce fertility in either men or women.

However, speak to a pharmacist or your doctor before taking it if you're trying to get pregnant.

If you or your child take Orixyl as a liquid medicine, it can stain your teeth. This doesn't last and should go after brushing your teeth well.

Orixyl capsules don't stain teeth.

Yes, Orixyl shouldn't affect you being able to drive or cycle.

You can eat and drink normally while taking Orixyl.

Yes, you can drink alcohol with Orixyl.

It's possible that a straightforward urinary tract infection (UTI) may clear up on its own without any treatment. However, it's usually best to treat a UTI with an antibiotic, or it could spread to the kidneys and lead to more serious problems.

Once treated, there are steps you can take to stop UTIs coming back:

  • do not use perfumed bubble bath, soap or talcum powder around your genitals - use plain, unperfumed products, and have a shower rather than a bath
  • go to the toilet as soon as you need to pee and always empty your bladder fully
  • stay well hydrated - aim to drink 6 to 8 glasses of fluid a day (water, lower-fat milk and sugar-free drinks, including tea and coffee, all count)
  • wipe your bottom from front to back when you go to the toilet
  • empty your bladder as soon as possible after having sex
  • do not use a contraceptive diaphragm or condoms with spermicidal lubricant on them - use another type of contraception instead
  • wear underwear made from cotton, rather than synthetic material like nylon, and avoid tight jeans and trousers

Although they won't do any harm, there's little evidence to show drinking cranberry juice or taking cranberry supplements helps treat or prevent UTIs.

Yellowing of the eyes or skin

Jaundice is a yellow color in the skin, the mucous membranes, or the eyes. The yellow pigment is from bilirubin, a byproduct of old red blood cells. If you’ve ever had a bruise, you may have noticed that the skin went through a series of color changes as it healed. When you saw yellow in the bruise, you were seeing bilirubin.

This effect, and liver damage or injury, can also be caused by Orixyl. The liver injury can even occur after Orixyl doses have stopped. This is more likely to happen when taking Orixyl with clavulanate.

Recognizing early symptoms such as fatigue, poor appetite, and vomiting can help prevent jaundice from worsening. Talk to your doctor if you experience any of these symptoms.

Before taking Orixyl, tell your doctor if you have or have ever had liver damage.

What are the side effects of Orixyl?

Side effects due to Orixyl include

People who are allergic to the cephalosporin class of antibiotics, which are related to the penicillins, for example, cefaclor (Ceclor), cephalexin (Keflex), and cefprozil (Cefzil), may or may not be allergic to penicillins.

Serious but rare reactions include:

Orixyl can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting Orixyl (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.

Important: if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic. Do not take any more Orixyl and speak with your doctor or go to your local accident and emergency department straightaway.

If you experience any other symptoms which you think may be due to the antibiotic, speak with your doctor or pharmacist for further advice.

How to take it

Swallow Orixyl capsules whole with a drink of water. Do not chew or break them.

Orixyl is available as a liquid for children and people who find it difficult to swallow tablets.

If you or your child are taking Orixyl as a liquid, it will usually be made up for you by your pharmacist. The medicine will come with a plastic syringe or spoon to help you measure out the right dose.

If you don't have one, ask your pharmacist for one. Do not use a kitchen teaspoon as it will not give the right amount.

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