Oflomac

Oflomac

  • Active Ingredient: Ofloxacin
  • 400 mg, 200 mg
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What is Oflomac?

The active ingredient of Oflomac brand is ofloxacin. Ofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Ofloxacin, USP is an off-white to pale yellow crystalline powder. The molecule exists as a zwitterion at the pH conditions in the small intestine. The relative solubility characteristics of Ofloxacin, USP at room temperature, as defined by USP nomenclature, indicate that Ofloxacin, USP is considered to be soluble in aqueous solutions with pH between 2 and 5. It is sparingly to slightly soluble in aqueous solutions with pH 7 (solubility falls to 4 mg/mL) and freely soluble in aqueous solutions with pH above 9. Ofloxacin, USP has the potential to form stable coordination compounds with many metal ions. This in vitro chelation potential has the following formation order: Fe +3 > Al +3 > Cu +2 > Ni +2 > Pb +2 > Zn +2 > Mg +2 > Ca +2 > Ba +2.

Used for

Oflomac is used to treat diseases such as: Anthrax, Anthrax Prophylaxis, Bladder Infection, Bone infection, Bronchitis, Campylobacter Gastroenteritis, Cervicitis, Chancroid, Chlamydia Infection, Epididymitis, Non-Specific, Epididymitis, Sexually Transmitted, Gonococcal Infection, Disseminated, Gonococcal Infection, Uncomplicated, Joint Infection, Kidney Infections, Methicillin-Resistant Staphylococcus Aureus Infection, Mycobacterium avium-intracellulare, Treatment, Nongonococcal Urethritis, Pelvic Inflammatory Disease, Plague, Pneumonia, Prostatitis, Salmonella Enteric Fever, Salmonella Gastroenteritis, Shigellosis, Skin or Soft Tissue Infection, Traveler's Diarrhea, Tuberculosis, Active, Urinary Tract Infection.

Side Effect

Possible side effects of Oflomac include: increased menstrual flow or vaginal bleeding; diarrhea; shakiness in the legs, arms, hands, or feet; loss of interest or pleasure; difficulty with breathing, chewing, speaking, or swallowing.

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Oflomac Pictures

By Lynn Marks | Medically Reviewed by Robert Jasmer, MD

Latest Update: 2016-03-28 Copyright © 2014 Everyday Health Media, LLC

What Are Side Effects Associated with Using Oflomac?

Common side effects of Oflomac include:

Less common side effects of Oflomac include:

This is not a complete list of side effects and other serious side effects may occur. Call your doctor for information and medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What Is Oflomac (Floxin)?

Oflomac is an antibiotic drug used to treat bacterial infections.

It's commonly used as an eye drop to treat conjunctivitis (pink eye) and corneal ulcers.

The tablet form of Oflomac is prescribed for various bacterial infections, such as pneumonia, bronchitis, urinary tract infections (UTI), gastrointestinal infections, prostate infections caused by E. coli, skin infections, and some sexually transmitted diseases.

It may also be used to prevent or treat anthrax or plague in certain people.

The medicine also comes as an ear drop to treat middle and outer ear infections.

Oflomac belongs to a class of drugs called fluoroquinolone antibiotics. It works by killing harmful bacteria that cause infection.

The U.S. Food and Drug Administration (FDA) approved Oflomac in 1990. It's sold under different brand names and manufactured by various companies.

How should this medicine be used?

Oflomac comes as a tablet to take by mouth. It is usually taken with or without food twice a day for 3 days to 6 weeks. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take Oflomac. Take Oflomac at around the same times every day and try to space your doses 12 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Oflomac exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

You should begin to feel better during the first few days of your treatment with Oflomac. If your symptoms do not improve or if they get worse, call your doctor.

Take Oflomac until you finish the prescription, even if you feel better. Do not stop taking Oflomac without talking to your doctor unless you experience certain serious side effects that are listed in the IMPORTANT WARNING and SIDE EFFECT sections. If you stop taking Oflomac too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Pediatric Use

Safety and effectiveness in infants below the age of one year have not been established. Quinolones, including Oflomac, have been shown to cause arthropathy in immature animals after oral administration; however, topical ocular administration of Oflomac to immature animals has not shown any arthropathy. There is no evidence that the ophthalmic dosage form of Oflomac has any effect on weight bearing joints.

Carcinogenesis, Mutagenesis, Impairment of Fertility

Long term studies to determine the carcinogenic potential of Oflomac have not been conducted.

Oflomac was not mutagenic in the Ames test, in vitro and in vivo cytogenic assay, sister chromatid exchange assay (Chinese hamster and human cell lines), unscheduled DMA synthesis (UDS) assay using human fibroblasts, the dominant lethal assay, or mouse micronucleus assay. Oflomac was positive in the UDS test using rat hepatocyte, and in the mouse lymphoma assay.

In fertility studies in rats, Oflomac did not affect male or female fertility or morphological or reproductive performance at oral dosing up to 360 mg/kg/day (equivalent to 4000 times the maximum recommended daily ophthalmic dose).

What Other Drugs Interact with Oflomac?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Oflomac has no known severe interactions with other drugs.

Oflomac has serious interactions with at least 42 different drugs.

Oflomac has moderate interactions with at least 162 different drugs.

Oflomac has mild interactions with at least 94 different drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

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Eye infections are a common cause of conjunctivitis. In conjunctivitis, your eye becomes inflamed, feels gritty, and may water more than usual. The white of your eye may look red, and your eyelids may become swollen and stuck together with a discharge when you wake up in the morning. Only one eye may be infected to begin with, but it often spreads to both eyes. Most cases of infective conjunctivitis clear within a week or so without treatment. For more severe infections, or for infections which do not clear on their own, an antibiotic eye drop such as Oflomac can be used.

Is Oflomac safe to take while pregnant or breastfeeding?

Oflomac should be avoided during pregnancy because it is secreted in breast milk and can cause adverse events in the infant.

Oflomac should be avoided in nursing mothers, as safe use has not been established.

Oflomac Overdose

Symptoms of an Oflomac overdose may include:

  • Dizziness
  • Drowsiness
  • Nausea
  • Hot and cold flashes
  • Slurred speech
  • Confusion
  • Numbness or swelling of the face

If you suspect an overdose, contact a poison control center or emergency room immediately.

You can get in touch with a poison control center at 800-222-1222.

How is this medicine (Oflomac) best taken?

Use Oflomac (ophthalmic) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • To gain the most benefit, do not miss doses.
  • Use as you have been told, even if your signs get better.
  • Use Oflomac (ophthalmic) at the same time of day.
  • For the eye only.
  • Wash your hands before and after use.
  • Do not touch the container tip to the eye, lid, or other skin.
  • When using, tilt your head back.
  • Gently pull down the lower lid and squeeze in how much the doctor told you to use.
  • After use, keep your eyes closed. Put pressure on the inside corner of the eye. Do this for 1 to 2 minutes. This keeps the drug in your eye.
  • Avoid wearing contacts unless told to wear them by your doctor.

What do I do if I miss a dose?

  • Use a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not use 2 doses at the same time or extra doses.

INDICATIONS

Oflomac ophthalmic solution is indicated for the treatment of infections caused by susceptible strains of the following bacteria in the conditions listed below:

What do I need to tell my doctor BEFORE I take Oflomac?

  • If you have an allergy to Oflomac or any other part of Oflomac (ophthalmic).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are breast-feeding or plan to breast-feed.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Oflomac (ophthalmic) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.


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