What other drugs will affect Nobactam?
Other drugs may interact with Nobactam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Mixing Nobactam with herbal remedies and supplements
There are no known problems with taking herbal remedies and supplements alongside Nobactam.
On this page
- About Nobactam
- Key facts
- Who can and can't take Nobactam
- How and when to take it
- Side effects
- How to cope with side effects
- Pregnancy and breastfeeding
- Cautions with other medicines
- Common questions
Q: My allergist has me on a 30 day regimen of 4 prednisone daily for 1 week, 3 the next week, 2 the next and 1 the 4th week. At the same time, I'm to take 1 Nobactam twice daily. Now, in the 3rd week, I'm feeling a lot of stomach pain and wonder if this is related?
A: Stomach pain and/or cramping is a common side effect of Nobactam. Other common side effects include nausea, vomiting, and diarrhea. Contact your healthcare provider right away if the stomach pain is severe or accompanied by diarrhea, blood in your stool, fever, yellowing of the skin, loss of appetite, dark urine, or clay-colored stools. You may also find helpful information at //www.everydayhealth.com/drugs/Nobactam Sarah McKenney Lewis, PharmD
1. About Nobactam
Nobactam is an antibiotic.
It's used in children, often to treat ear infections and chest infections.
The medicine is only available on prescription. It comes as capsules or as a liquid that you drink. It's also given by injection, but this is usually only done in hospital.
How does Nobactam work?
Nobactam works by inhibiting the formation of bacterial cell walls.
What should I discuss with my veterinarian before giving Nobactam to my pet?
Tell your veterinarian if your pet has ever had an allergic reaction to another penicillin or to a cephalosporin. Tell your veterinarian if your pet has kidney disease or stomach or intestinal disease.
Nobactam s >
Nobactam is a penicillin antibiotic used to treat bacterial infections, including bronchitis, pneumonia, and infections of the ear, nose, throat, skin, and urinary tract. Though it can be highly effective in treating bacterial infections, it also comes with a list of potential side effects.
Among the more common side effects for Nobactam (Amoxil, Trimox) are:
Less common side effects include:
- allergic reactions like itching or hives, swelling of the face, lips, or tongue
- breathing problems
- blistering, peeling, or loosening of the skin, including inside the mouth
- trouble sleeping
- trouble passing urine, dark urine, or a decrease in the quantity of urine
- unusually weak or tired
- unusual bleeding or bruising
- yellowing of the eyes or skin
Q: Is antibiotic Nobactam compatible with the drug acylovir?
A: There is no known interaction or incompatibility between Nobactam/clavulanate potassium and acyclovir. Gregory Latham, RPh
125 mg/5 mL, 200 mg/5 mL, 250 mg/5 mL, 400 mg/5 mL. Each 5 mL of reconstituted strawberry-flavored suspension contains 125 mg Nobactam as the trihydrate. Each 5 mL of reconstituted bubble-gumflavored suspension contains 200 mg, 250 mg or 400 mg Nobactam as the trihydrate.
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Nobactam is sometimes used to get rid of Helicobacter pylori. This is an infection often found in people with stomach ulcers. If you are prescribed it for this reason, you will also be prescribed other medicines to take alongside it.
What is Nobactam?
Nobactam is a broad-spectrum penicillin antibiotic used to treat various infections caused by susceptible strains of bacteria. Nobactam is sold per capsule or per tablet and requires a prescription from your veterinarian.
NOTE: Nobactam is also available in a suspension as Nobactam Drops.
When available, the clinical microbiology laboratory should provide cumulative in vitro susceptibility test results for antimicrobial drugs used in local hospitals and practice areas to the physician as periodic reports that describe the susceptibility profile of nosocomial and community-acquired pathogens. These reports should aid the physician in selecting the most effective antimicrobial.
Dilution Techniques: Quantitative methods are used to determine antimicrobial minimum inhibitory concentrations (MICs). These MICs provide estimates of the susceptibility of bacteria to antimicrobial compounds. The MICs should be determined using a standardized test method -(broth or agar) 2,4 . The MIC values should be interpreted according to the criteria in Table 4.
Diffusion Techniques: Quantitative methods that require measurement of zone diameters can also provide reproducible estimates of the susceptibility of bacteria to antimicrobial compounds 3,4 . The zone size should be determined using a standardized test method 3 .
Susceptibility to Nobactam of Enterococcus spp., Enterobacteriaceae, and H. influenzae, may be inferred by testing ampicillin 4 . Susceptibility to Nobactam of Staphylococcus spp., and beta-hemolytic Streptococcus spp., may be inferred by testing penicillin 4 . The majority of isolates of Enterococcus spp. that are resistant to ampicillin or Nobactam produce a TEM-type beta-lactamase. A beta-lactamase test can provide a rapid means of determining resistance to ampicillin and Nobactam 4 .
Susceptibility to Nobactam of Streptococcus pneumoniae (non-meningitis isolates) may be inferred by testing penicillin or oxacillin 4 . The interpretive criteria for S. pneumoniae to Nobactam are provided in Table 4 4 .
Table 4: Susceptibility Interpretive Criteria for Nobactam
A report of “Susceptible” indicates the antimicrobial is likely to inhibit growth of the pathogen if the antimicrobial compound reaches a concentration at the infection site necessary to inhibit growth of the pathogen. A report of “Intermediate” indicates that the result should be considered equivocal, and, if the microorganism is not fully susceptible to alternative, clinically feasible drugs, the test should be repeated. This category implies possible clinical applicability in body sites where the drug is physiologically concentrated. This category also provides a buffer zone that prevents small uncontrolled technical factors from causing major discrepancies in interpretation. A report of “Resistant” indicates the antimicrobial is not likely to inhibit growth of the pathogen if the antimicrobial compound reaches the concentration usually achievable at the infection site; other therapy should be selected.
Use In Patients With Mononucleosis
A high percentage of patients with mononucleosis who receive Nobactam develop an erythematous skin rash. Thus Nobactam should not be administered to patients with mononucleosis.
Abnormal prolongation of prothrombin time (increased international normalized ratio ) has been reported in patients receiving Nobactam and oral anticoagulants. Appropriate monitoring should be undertaken when anticoagulants are prescribed concurrently. Adjustments in the dose of oral anticoagulants may be necessary to maintain the desired level of anticoagulation.