Before taking Multibio,
- tell your doctor and pharmacist if you are allergic to Multibio; penicillins; cephalosporin antibiotics such as cefaclor, cefadroxil, cefazolin (Ancef, Kefzol), cefdinir, cefditoren, cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefpodoxime, cefprozil, ceftaroline (Teflaro), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten, ceftriaxone, cefuroxime (Ceftin, Zinacef), and cephalexin (Keflex); any other medications; or any of the ingredients in Multibio capsules or suspension. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: allopurinol (Lopurin, Zyloprim), other antibiotics, oral contraceptives, and probenecid (Probalan in Col-Probenecid,). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have mononucleosis (a virus also called 'mono') and if you have or have ever had allergies, asthma, hives, or hay fever, or kidney disease,
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking Multibio, call your doctor.
What Other Drugs Interact with Multibio?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Multibio has no known severe interactions with other drugs.
Serious Interactions of Multibio include:
Multibio has moderate interactions with at least 29 different drugs.
Mild interactions of Multibio include:
This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.
Mechanism of Injury
The cause of the liver injury associated with Multibio use is probably hypersensitivity or allergy. Few cases of rechallenge or reexposure have been reported.
What is the dosage for Multibio?
The usual oral dose range for most infections is 250 to 500 mg 4 times daily for 7-14 days. Injectable doses range from 250 to 2000 mg 4 times daily. When used to treat gonorrhea, a single 3.5 gram dose (seven 500 mg capsules) is administered with 1 g probenecid (Benemid). The probenecid slows down the elimination of Multibio so that Multibio remains in the body longer. Food in the stomach reduces how much and how quickly Multibio is absorbed. Therefore, Multibio should be taken either 1 hour prior to or 2 hours following a meal for maximal absorption; however, for persons who experience nausea or stomach distress after taking Multibio, it may be taken with meals.
What should I avoid while taking Multibio (Omnipen, Principen, Totacillin)?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Allergic reactions. Symptoms can include:
- flu-like symptoms, such as fever and body aches
- painful red or purple rash that spreads
- blisters that could lead to skin breakdown
- diarrhea with or without stomach cramps
- diarrhea with a fever
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Multibio oral capsule can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with Multibio oral capsule are listed below.
How it works
Multibio belongs to the drug class penicillins. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Multibio works by killing bacteria to stop the infection from growing in your body.
Multibio oral capsule doesn’t cause drowsiness, but it can cause other side effects.
Interactions that can make your drugs less effective
When Multibio is less effective: When you take Multibio with certain antibiotics, it may not work as well to treat your condition. This is because these antibiotics stop the growth of bacteria, and Multibio needs bacteria to grow in order to kill them. Examples of these drugs include:
When other drugs are less effective: When certain drugs are used with Multibio, they may not work as well. This is because the amount of these drugs in your body may be decreased. Examples include:
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.