Moxan for Dogs
Moxan is often prescribed for dogs and cats that have bacterial infections.
Amoxi-Tabs is one brand name of this antibiotic; it's also available as a capsule and a liquid.
Moxan is usually well-tolerated by most pets, and side effects are few. The drug can be given with food.
Give Moxan to your dog or cat according to your veterinarian's instructions, and don't stop giving the drug until the entire course of treatment is completed.
Q: My allergist has me on a 30 day regimen of 4 prednisone daily for 1 week, 3 the next week, 2 the next and 1 the 4th week. At the same time, I'm to take 1 Moxan twice daily. Now, in the 3rd week, I'm feeling a lot of stomach pain and wonder if this is related?
A: Stomach pain and/or cramping is a common side effect of Moxan. Other common side effects include nausea, vomiting, and diarrhea. Contact your healthcare provider right away if the stomach pain is severe or accompanied by diarrhea, blood in your stool, fever, yellowing of the skin, loss of appetite, dark urine, or clay-colored stools. You may also find helpful information at //www.everydayhealth.com/drugs/Moxan Sarah McKenney Lewis, PharmD
Pregnancy Category B. Reproduction studies have been performed in mice and rats at doses up to 2000 mg/kg (3 and 6 times the 3 g human dose, based on body surface area). There was no evidence of harm to the fetus due to Moxan. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, Moxan should be used during pregnancy only if clearly needed.
See to it you constantly take Moxan as suggested, observing the amount extremely carefully. It's particularly important to take the whole quantity of this medication suggested, as quiting before it's time may result in a relapse of infection. Your blood, along with your renal or liver function need to be checked before you could securely take Moxan. Make sure you see your medical service provider routinely to see if every little thing is going equally as planned.
Other information about Moxan
- Moxan is available in generic form and is available by prescription only.
- Brand names available in the US for Moxan are Amoxil, Moxatag, and Larotid.
Resistance to Moxan is mediated primarily through enzymes called beta-lactamases that cleave the beta-lactam ring of Moxan, rendering it inactive.
Moxan has been shown to be active against most isolates of the bacteria listed below, both in vitro and in clinical infections as described in the INDICATIONS AND USAGE section.
H. pylori Eradication To Reduce The Risk Of Duodenal Ulcer Recurrence
Randomized, double-blind clinical studies performed in the United States in patients with H. pylori and duodenal ulcer disease (defined as an active ulcer or history of an ulcer within 1 year) evaluated the efficacy of lansoprazole in combination with Moxan capsules and clarithromycin tablets as triple 14-day therapy, or in combination with Moxan capsules as dual 14-day therapy, for the eradication of H. pylori. Based on the results of these studies, the safety and efficacy of 2 different eradication regimens were established: Triple therapy: Moxan 1 gram twice daily/clarithromycin 500 mg twice daily/lansoprazole 30 mg twice daily (see Table 6). Dual therapy: Moxan 1 gram three times daily/lansoprazole 30 mg three times daily (see Table 7. All treatments were for 14 days. H. pylori eradication was defined as 2 negative tests (culture and histology) at 4 to 6 weeks following the end of treatment. Triple therapy was shown to be more effective than all possible dual therapy combinations. Dual therapy was shown to be more effective than both monotherapies. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.
Table 6: H. pylori Eradication Rates When Moxan is Administered as Part of a Triple Therapy Regimen
Table 7: H. pylori Eradication Rates When Moxan is Administered as Part of a Dual Therapy Regimen
1. Swanson-Biearman B, Dean BS, Lopez G, Krenzelok EP. The effects of penicillin and cephalosporin ingestions in children less than six years of age. Vet Hum Toxicol. 1988; 30: 66-67.
2. Clinical and Laboratory Standards Institute (CLSI). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically; Approved Standard – Tenth Edition. CLSI document M07-A10, Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA, 2015.
3. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Disk Diffusion Susceptibility Tests; Approved Standard – Twelfth Edition. CLSI document M02-A12, Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA, 2015.
4. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing; Twenty-fifth Informational Supplement, CLSI document M100-S25. CLSI document M100-S25, Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087, USA, 2015.
Mixing Moxan with herbal remedies and supplements
There are no known problems with taking herbal remedies and supplements alongside Moxan.
Interactions that increase the risk of side effects from other drugs
Taking Moxan with certain medications raises your risk of side effects from these medications. Moxan increases the amount of these drugs in your body.
Examples of these drugs include drugs to treat blood clots. If you use them with Moxan, you have a higher risk of bleeding.
Probenecid decreases the renal tubular secretion of Moxan. Concurrent use of Moxan and probenecid may result in increased and prolonged blood levels of Moxan.
Q: Moxan suspension was left out of refrigerator for about 11 hours over night. Is is dangerous to give to our 8 year old? Has it gone bad?
A: According to Pharmacist's Letter, Moxan suspension can be kept at room temperature for at least 10 days. Although refrigeration improves taste, it is not needed to maintain the potency or safety of the drug. For more health information, visit everydayhealth.com and sign up for free newsletters.
What are the potential side effects of Moxan?
Contact your veterinarian immediately if the pet experiences severe or bloody diarrhea during treatment. Stop giving Moxan and seek emergency veterinary medical care in the event of an allergic reaction (shortness of breath; hives; swelling of the lips, tongue, or face; rash; or fainting), seizures, unusual bleeding, or bruising. Other less serious side effects such as mild nausea, vomiting, diarrhea or abdominal pain, or yeast or fungal infection may be more likely to occur. Continue to give Moxan and notify your veterinarian if these symptoms occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.
Q: I was prescribed Moxan 500 mg every eight hours. How much passes to my breast milk, and how much will this affect my baby?
A: Moxan is an antibiotic in the penicillin group of drugs. It fights bacteria in your body. Moxan is used to treat many types of infections caused by bacteria, such as ear infections, bladder infections, pneumonia, gonorrhea, and E. coli or salmonella infection. Penicillins have been shown to be excreted in human milk. Moxan use by nursing mothers may lead to sensitization of infants. Caution should be exercised when Moxan is administered to a nursing woman. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.
Important: if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic. Do not take any more Moxan and speak with your doctor or go to your local accident and emergency department straightaway.
If you experience any other symptoms which you think may be due to the antibiotic, speak with your doctor or pharmacist for further advice.
Moxan is similar to penicillin in its bactericidal action against susceptible bacteria during the stage of active multiplication. It acts through the inhibition of cell wall biosynthesis that leads to the death of the bacteria.
Dizziness occurs when you feel lightheaded, like you might faint, being unsteady, or experiencing a loss of balance or vertigo (a feeling that you or the room is spinning or moving).
Most causes of dizziness are not serious and either quickly get better on their own or are easily treated.
Tell your doctor all of the medications you are currently taking before they prescribe you Moxan. To prevent dizziness, avoid drinking alcohol when on Moxan.
Avoid driving until you know how Moxan will affect you. If you get dizzy, sit down for a moment and see if it passes. Keep your head elevated with a pillow if you lie down.
Dizziness may be a symptom of anemia or an allergic reaction.
If dizziness is severe or combined with symptoms like shortness of breath or swelling of the lips, face, or tongue, a severe allergic reaction could be present. Seek immediate medical attention.