Monodoks tablets


  • Active Ingredient: Doxycycline
  • 200 mg, 100 mg
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What is Monodoks?

The active ingredient of Monodoks brand is doxycycline. Doxycycline is a tetracycline antibiotic that fights bacteria in the body.

Used for

Monodoks is used to treat diseases such as: Acne, Actinomycosis, Amebiasis, Anthrax, Anthrax Prophylaxis, Bacterial Infection, Bartonellosis, Bronchiectasis, Bronchitis, Brucellosis, Bullous Pemphigoid, Cervicitis, Chancroid, Chlamydia Infection, Cholera, Cutaneous Bacillus anthracis, Ehrlichiosis, Enterocolitis, Epididymitis, Sexually Transmitted, Gastroenteritis, Gonococcal Infection, Uncomplicated, Granuloma Inguinale, Inclusion Conjunctivitis, Lyme Disease, Lyme Disease, Arthritis, Lyme Disease, Carditis, Lyme Disease, Erythema Chronicum Migrans, Lyme Disease, Neurologic, Lymphogranuloma Venereum, Malaria, Malaria Prevention, Melioidosis, Mycoplasma Pneumonia, Nongonococcal Urethritis, Ocular Rosacea, Ornithosis, Pelvic Inflammatory Disease, Pemphigoid, Pemphigus, Periodontitis, Plague, Pleural Effusion, Pneumonia, Proctitis, Prostatitis, Psittacosis, Q Fever, Rabbit Fever, Rheumatoid Arthritis, Rickettsial Infection, Rosacea, Skin or Soft Tissue Infection, STD Prophylaxis, Syphilis, Early, Syphilis, Latent, Tertiary Syphilis, Trachoma, Upper Respiratory Tract Infection, Urinary Tract Infection.

Side Effect

Possible side effects of Monodoks include: sore throat; difficulty with swallowing; sores in the mouth; clay-colored stools; unusual weight loss; cough.

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Postmarketing Experience

The following adverse reactions have been identified during post-approval use of Monodoks. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate a causal relationship to drug exposure.

Due to oral Monodoks's virtually complete absorption, side effects to the lower bowel, particularly diarrhea, have been infrequent. The following adverse reactions have been observed in patients receiving tetracyclines:

Gastrointestinal: Anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis, and inflammatory lesions (with monilial overgrowth) in the anogenital region. Hepatotoxicity has been reported. These reactions have been caused by both the oral and parenteral administration of tetracyclines. Esophagitis and esophageal ulcerations have been reported in patients receiving capsule and tablet forms of drugs in the tetracycline-class. Most of these patients took medications immediately before going to bed .

Skin: Maculopapular and erythematous rashes, Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis, and erythema multiforme have been reported. Photosensitivity is discussed above .

Renal: Rise in BUN has been reported and is apparently dose-related .

Intracranial Hypertension: Intracranial hypertension (IH, pseudotumor cerebri) has been associated with the use of tetracycline

Thyroid Gland Changes: When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of thyroid glands. No abnormalities of thyroid function are known to occur.


Use of tetracyclines during tooth development (last half of pregnancy through age 8 years) can cause permanent discoloration of teeth; use Monodoks in pediatric patients 8 years of age or less only when potential benefits expected to outweigh risks in severe or life-threatening conditions (eg, anthrax, Rocky Mountain spotted fever); particularly when there are no alternative therapies

Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, and may range in severity from mild diarrhea to fatal colitis

Photosensitivity manifested by an exaggerated sunburn reaction has been observed in some individuals taking tetracyclines

May result in overgrowth of non-susceptible organisms, including fungi. If such infections occur, discontinue use and institute appropriate therapy

Severe skin reactions, such as exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS) reported; if severe skin reactions occur, discontinue therapy immediately and institute appropriate therapy

Intracranial hypertension (pseudotumor cerebri) reported (rare) may occur; symptoms include headache, blurred vision, diplopia, and vision loss; papilledema can be found on funduscopy; women of childbearing age who are overweight or have a history of IH are at greater risk; possibility for permanent visual loss exists; if visual disturbance occurs during treatment, prompt ophthalmologic evaluation is warranted; intracranial pressure can remain elevated for weeks after drug cessation; monitor until they stabilize

All tetracyclines form a stable calcium complex in any bone-forming tissue; decrease in fibula growth rate has been observed in prematures given an oral tetracycline; reaction was shown to be reversible when the drug was discontinue

Antianabolic action of the tetracyclines may cause an increase in BUN; studies to date indicate that this does not occur with the use of Monodoks in patients with impaired renal function

Monodoks offers substantial but not complete suppression of the asexual blood stages of Plasmodium strains

Prescribing Monodoks in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria

In long-term therapy, periodic laboratory evaluation of organ systems, including hematopoietic, perform renal and hepatic studies

Rated Monodoks (Oracea, Doryx) for Otitis Media Report

Worst drug I have ever taken.6 days off still experiencing fatigue extreme nausea and anxiety .Never been anxious before.I am very frightened that these will be long term side effects.

Serious Side Effects of Monodoks

Serious side effects of Monodoks can also occur.

If you have any of these side effects, stop taking Monodoks and call your doctor right away:

  • Severe headache
  • Blurry vision
  • Rash or hives
  • Trouble breathing or swallowing
  • Sunburn
  • Yellowing of the skin or eyes
  • Dark-colored urine
  • Light-colored bowel movements
  • Loss of appetite
  • Nausea or vomiting
  • Stomach pain
  • Extreme tiredness or weakness
  • Confusion
  • Less frequent urination

Q: I was positive for Lyme disease. I took Monodoks and most of the symptoms have cleared up. Is there another test that is done to see if the disease is gone or do they do the same blood test that diagnosed it?

A: Lyme disease is an infection that is transmitted to humans through a tick bite. Ticks become infected by feeding on an infected animal. Some of the common symptoms of Lyme disease are rash, fever, headache, muscle pain, fatigue, or joint pain. The most common symptom is a rash that occurs about 1 to 2 weeks after a tick bite, but may occur up to 36 days post-bite. Monodoks is one of the most frequently used antibiotics for the treatment of Lyme disease. Usually, a follow-up appointment should take place about 1 to 2 weeks after symptoms resolve. Further testing is not usually performed because a positive test result can appear for years after the initial infection. It is recommended that you follow-up with your healthcare provider to ensure that the course of antibiotic therapy was effective. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Megan Uehara, PharmD

Monodoks for Acne

For many years, doctors have prescribed Monodoks to treat acne.

It's sometimes used as an alternative to another acne drug with more side effects, minocycline.

However, a study published in 2015 found that people with acne who used an antibiotic-free facial gel had greatly improved acne, according to MedPage Today.

The study suggests that using the facial gel containing adapalene/benzoyl peroxide might be a better alternative than using antibiotics such as Monodoks for acne.

How should I take Monodoks?

Take Monodoks exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Monodoks with a full glass of water. Drink plenty of liquids while you are taking this medicine.

Most brands of doxycyline may be taken with food or milk if the medicine upsets your stomach. Different brands of Monodoks may have different instructions about taking them with or without food.

Take Oracea on an empty stomach, at least 1 hour before or 2 hours after a meal.

You may open a regular capsule or break up a regular tablet and sprinkle the medicine into a spoonful of applesauce to make swallowing easier. Swallow right away without chewing. Do not save the mixture for later use. Drink a full glass (8 ounces) of cool water right away.

Do not crush, break, or open a delayed-release capsule or tablet. Swallow the pill whole.

You may need to split a Monodoks tablet to get the correct dose. Follow your doctor's instructions.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

If you take Monodoks to prevent malaria: Start taking the medicine 1 or 2 days before entering an area where malaria is common. Continue taking the medicine every day during your stay and for at least 4 weeks after you leave the area. Use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria.

Monodoks is usually given by injection only if you are unable to take the medicine by mouth. A healthcare provider will give you this injection as an infusion into a vein.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Monodoks will not treat a viral infection such as the flu or a common cold.

If you need surgery, tell the surgeon ahead of time that you are using Monodoks.

Store at room temperature away from moisture, heat and light.

Throw away any unused medicine after the expiration date on the label has passed. Using expired Monodoks can cause damage to your kidneys.

2. Key facts

  • For most infections, you'll start to feel better in a few days but it is important to finish the course of medicine.
  • The most common side effects of Monodoks are headaches, feeling or being sick. It can also make your skin sensitive to the sun.
  • Monodoks can affect growing teeth so it's not prescribed for children under 12 years old or given to pregnant and breastfeeding women.
  • Do not drink alcohol while taking Monodoks. There are also some common medicines you should not mix with it.
  • Monodoks can also be called by the brand name Vibramycin-D.
About where to purchase Dumaflox tablets for treat Plague Prophylaxis

Drug interaction overview

  • Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage
  • Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracyclines in conjunction with penicillin
  • Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate, and iron-containing preparations
  • Concurrent use of tetracyclines, may render oral contraceptives less effective
  • Barbiturates, carbamazepine, and phenytoin decrease the half-life of Monodoks
  • Coadministration of tetracycline and methoxyflurane has been reported to result in fatal renal toxicity
  • False elevations of urinary catecholamines may occur due to interference with the fluorescence test

Q: Is Monodoks different than Malarone?

A: Monodoks is a tetracycline-type antibiotic used to treat bacterial infections (e.g., Rickettsial infections, sexually transmitted infections, respiratory tract infections, ophthalmic infections, Anthrax, adjunctive therapy in acute intestinal amebiasis and severe acne, and prophylaxis of malaria). The most common side effects reported with tetracyclines include anorexia, nausea, vomiting, diarrhea, rash, photosensitivity, urticaria, and hemolytic anemia. Malarone is a combination of atovaquone and proguanil. These medications are used to treat and prevent malaria. Malaria is caused by parasites and these drugs work to inhibit the growth to the parasites in the human body. Malarone is associated with headache, cough, abdominal pain, and vomiting, nausea, diarrhea, weakness and dizziness. Monodoks should be taken with plenty of fluids to minimize stomach irritation. Monodoks should not be taken with dairy products or high-fat foods. Malarone should be taken with food to minimize stomach upset. Michelle McDermott, RPh, PharmD

By Mary Elizabeth Dallas | Medically Reviewed by Niya Jones, MD, MPH

Latest Update: 2014-07-31 Copyright © 2014 Everyday Health Media, LLC

When penicillin is contraindicated, Monodoks is an alternative treatment of the following infections:

  • Syphilis caused by Treponema pallidum
  • Yaws caused by Treponema pallidum subspecies pertenue
  • Vincent’s infection caused by Fusobacterium fusiforme
  • Actinomycosis caused by Actinomyces israelii. Infections caused by Clostridium species
  • Syphilis ( 8 years, 8 years, ≥45 kg

What Other Drugs Interact with Monodoks?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Severe Interactions of Monodoks include:

Monodoks has serious interactions with at least 67 different drugs.

Monodoks moderate interactions with at leas 51 different drugs.

Monodoks moderate interactions with at leas 32 different drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

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