Other uses for this medicine
Minac is also sometimes used to treat rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function). Talk to your doctor about the risks of using this medication for your condition.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
This medication contains Minac. Do not take Dynacin, Minocin, Minocin Kit, Solodyn, or Ximino if you are allergic to Minac or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
Effects of Minac on inflammatory bowel disease
The effects of Minac on experimental colitis were first described in 2009 by Huang et al. (2009b), who reported its ability to prevent and treat dextran sodium sulphate-induced colitis, significantly diminishing the mortality rate and attenuating the severity of the disease. These beneficial effects were associated with reduced iNOS and MMP expression in the intestinal tissue. Supporting these observations, Garrido-Mesa et al. (2011a) confirmed the intestinal anti-inflammatory effect of Minac in experimental models of colitis in both mice and rats, showing it to have a higher efficacy than other antibiotics like metronidazole, traditionally used to treat human inflammatory bowel disease, although it was devoid of immunomodulatory properties (Perencevich and Burakoff, 2006). That study proposed that Minac's ability to modulate both the immune and the microbiological parameters of the disease contribute to its beneficial effects. Regarding the latter, these studies revealed that the imbalance in the composition of the intestinal microbiota that characterizes experimental colitis was restored after Minac treatment, while the other antibiotics tested did not show this effect. Furthermore, in a mouse model of reactivated colitis, the association of Minac with the probiotic Escherichia coli Nissle 1917, which has been reported to show beneficial effects in these intestinal conditions (Schultz, 2008), exerted a greater intestinal anti-inflammatory effect than the individual treatments and, in addition, was able to attenuate the reactivation of the colitis (Garrido-Mesa et al., 2011b). Therefore, combined immunomodulatory and anti-microbial properties of Minac could be very useful in the treatment of multifactorial conditions, like inflammatory bowel disease.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to Minac.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking Minac.
Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the Minac, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
See also Side Effects section.
Before taking Minac, tell your doctor or pharmacist if you are allergic to it; or to other tetracyclines (such as doxycycline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, trouble swallowing, esophagus problems (such as hiatal hernia or reflux/heartburn).
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.
Minac may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Children younger than 8 years may be more sensitive to the side effects of Minac, especially tooth discoloration. Tooth discoloration has also occurred in older children and in young adults. Discuss the risks and benefits of this medication with the doctor.
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using Minac. Minac may harm an unborn baby. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
This medication passes into breast milk. Consult your doctor before breast-feeding.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Minac only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2019 Cerner Multum, Inc. Version: 15.01.
What is the dosage for Minac?
Adults (immediate-release tablets and capsules): The recommended dose for Minac is: 200 mg initially, followed by 100 mg every 12 hours. If more frequent doses are preferred, then two or four 50 mg capsules initially, followed by 500 mg 4 times a day.
Children 8 years of age and older (immediate-release tablets and capsules): The recommended dose of Minac is: 4 mg/kg initially, followed by 2 mg/kg every 12 hours, not to exceed the usual adult dose.
Adults and children 12 years of age and older (extended-release tablets): The recommended dose for Minac is: Approximately 1 mg/kg by mouth once daily for up to 12 weeks for the treatment of inflammatory lesions of non-nodular acne vulgaris.
Safe and effective use of Minac is not established for children under the age of 8.
How should this medicine be used?
Minac comes as a regular capsule, a pellet-filled capsule, and an extended-release tablet (Solodyn) to take by mouth. The capsule and pellet-filled capsule is usually taken twice a day (every 12 hours) or four times a day (every 6 hours). The extended-release tablet is usually taken once a day to treat acne. Minac can be taken with or without food. Drink a full glass of water with each dose. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Minac exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the pellet-filled capsules and extended-release tablets whole; do not split, chew, or crush them.
What should I avoid while taking Minac?
For 2 hours before or after you take Minac: Avoid taking antacids, laxatives, multivitamins, or supplements that contain calcium, magnesium, or iron. These other medicines can make it harder for your body to absorb Minac.
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Avoid exposure to sunlight or tanning beds. Minac can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Rated Minac for Acne Report
PLEASE ANYONE READING DO YOUR RESEARCH AND KEEP TRACK OF YOUR SIDE EFFECTS. I have never in my life dealt with anxiety, depression or any mental illness at all in my life before Minac. I started taking Minac and immediately became depressed, felt terrible everyday, constant chest pains and crying and I felt like I was out of my mind. I stopped taking the medication after two and a half months after reading these reviews. It did clear my skin completely but it was not worth the emotional pain I went through. Two months later I finally feel like I'm in control of myself again. I started getting a little bit of my acne back but it is nowhere near as bad as how it originally was before I started Minac nor do I know if it will get any worse again in the future. If I had known my mental health was affected by Minac earlier, I would've stopped then and there.
Before taking Minac,
- tell your doctor and pharmacist if you are allergic to Minac, tetracycline, doxycycline, demeclocycline, any other medications, or any of the ingredients in Minac capsules, pellet-filled capsules, or extended-release tablets. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Ergomar, in Cafergot, Migergot), and methylergonovine (Methergine); and penicillin. Also tell your doctor or pharmacist if you are taking isotretinoin (Absorica, Amnesteem, Clavaris, others) or have recently stopped taking it. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Minac decreases the effectiveness of some oral contraceptives; talk to your doctor about selecting another form of birth control to use while taking this medication.
- be aware that antacids containing magnesium, aluminum, or calcium, calcium supplements, zinc products, iron products, and laxatives containing magnesium interfere with Minac, making it less effective. Take Minac2 hours before or 6 hours after antacids , calcium supplements, and laxatives containing magnesium. Take Minac 2 hours before or 4 hours after iron preparations and vitamin products that contain iron. Take Minac 2 hours before or after zinc containing products.
- tell your doctor if you have or have ever had asthma, lupus (condition in which the immune system attacks many tissues and organs including the skin, joints, blood, and kidneys), intracranial hypertension (pseudotumor cerebri; high pressure in the skull that may cause headaches, blurry or double vision, vision loss, and other symptoms), or kidney or liver disease.
- you should know that Minac may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, or injections). Talk to your doctor about using another form of birth control.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking Minac, call your doctor immediately. Minac can harm the fetus.
- you should know that Minac may make you lightheaded or dizzy. Do not drive a car or operate machinery until you know how this medication affects you.
- plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Minac may make your skin sensitive to sunlight.
- you should know that when Minac is used during pregnancy or in babies or children up to age 8, it can cause the teeth to become permanently stained. Minac should not be used in children under age 8 except for inhalational anthrax or if your doctor decides it is needed.