Usual Adult Dose for Lymphogranuloma Venereum
Although Hostacyclins in general may be useful for the treatment of lymphogranuloma venereum, doxycycline is much more commonly used and is specifically recommended by the CDC as primary therapy for this disease. Therefore, the use of Hostacyclin for the treatment of this patient with lymphogranuloma venereum is not recommended. Doxycycline may be an effective alternative.
Hostacyclin and Other Interactions
Consuming dairy products, such as milk, yogurt, cheese, and ice cream, may interfere with the absorption of Hostacyclin. You should talk to your doctor about this interaction.
This medication may make your skin more sensitive to sunlight. You should avoid unnecessary or prolonged sun exposure while taking Hostacyclin.
What Is Hostacyclin and How Does It Work?
Hostacyclin is an antibiotic used to treat many different bacterial infections, such as urinary tract infections, acne, gonorrhea, chlamydia, and others.
Hostacyclin is available under the following different brand names: Sumycin, Actisite, and Achromycin V.
Common Side Effects of Hostacyclin
You should call your doctor if any of the following side effects become severe or do not go away:
- Upset stomach
- Sore mouth
- Skin color changes
- Rectum or vaginal itching
Usual Adult Dose for Tertiary Syphilis
500 mg orally every 6 hours for 28 days
Hostacyclin should be used only if penicillins are contraindicated.
- It is recommended that doxycycline not be taken at the same time as aluminum, magnesium, or calcium based antacids, such as Mylanta, Maalox, Tums, or Rolaids because, like food, these medications bind doxycycline in the intestine and prevent its absorption. Similarly, doxycycline should not be taken with minerals (such as calcium or iron) or with bismuth subsalicylate (Pepto Bismol).
- Doxycycline may enhance the activity of warfarin (Jantoven, Coumadin) and cause excessive "thinning" of the blood leading to exaggerated bleeding, necessitating a reduction in the dose of warfarin. Phenytoin (Dilantin), carbamazepine (Tegretol), and barbiturates (such as phenobarbital) may enhance the metabolism (destruction) of doxycycline thus making it less effective.
- Doxycycline may interfere with the action of penicillins and should not be combined with penicillins. It may also reduce the effect of oral contraceptives. Combining Hostacyclin and methoxyflurane (Penthrane) may reduce kidney function.
Nausea, vomiting, diarrhea, loss of appetite, mouth sores, black hairy tongue, sore throat, dizziness, headache, or rectal discomfort may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: nail discoloration, muscle pain, difficult or painful swallowing, signs of kidney problems (such as change in the amount of urine), brown/gray tooth discoloration, numbness/tingling of the hands/feet, unusual fatigue, new signs of infection (e.g., persistent sore throat, fever, chills), hearing changes (e.g., ringing in the ears, decreased hearing), easy bruising/bleeding, severe stomach/abdominal pain, yellowing eyes/skin, dark urine.
Hostacyclin may rarely cause a serious increase in pressure inside the skull (intracranial hypertension-IH). The risk of this side effect is greater for women of childbearing age who are overweight or who have had IH in the past. If IH develops, it usually goes away after Hostacyclin is stopped; however, there is a chance of permanent vision loss or blindness. Get medical help right away if you have: persistent/severe headache, vision changes (such as blurred/double vision, decreased vision, sudden blindness), persistent nausea/vomiting.
This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped.. Do not use anti-diarrhea or opioid medications if you have the following symptoms because these products may make them worse. Tell your doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool..
Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, skin lesions/sores, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, new or worsening swelling/pain in the joints, chest pain, fast/irregular heartbeat.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
What is Hostacyclin?
Hostacyclin is an antibiotic that fights infection caused by bacteria.
Hostacyclin is used to treat many different bacterial infections of the skin, intestines, respiratory tract, urinary tract, genitals, lymph nodes, and other body systems. It is often used in treating severe acne, or sexually transmitted diseases such as syphilis, gonorrhea, or chlamydia.
Hostacyclin is also used to treat infections you can get from direct contact with infected animals or contaminated food.
In some cases, Hostacyclin is used when penicillin or another antibiotic cannot be used to treat serious infections such as Anthrax, Listeria, Clostridium, Actinomyces, and others.
How to use Hostacyclin HCL
Hostacyclin works best when taken on an empty stomach 1 hour before or 2 hours after meals. If stomach upset occurs, ask your doctor if you can take this medication with food. Take each dose with a full glass of water (8 ounces or 240 milliliters) unless your doctor directs you otherwise. Do not lie down for at least 10 minutes after taking this medication. For this reason, do not take it right before bedtime.
Take this medication 2-3 hours before or after taking any products containing magnesium, aluminum, or calcium. Some examples include antacids, quinapril, certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), vitamins/minerals, and sucralfate. Follow the same instructions with dairy products (e.g., milk, yogurt), calcium-enriched juice, bismuth subsalicylate, iron, and zinc. These products bind with Hostacyclin, preventing its full absorption.
Dosage is based on your medical condition and response to therapy. For use in children older than 8 years of age, the dosage is also based on weight.
For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.
Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.
Inform your doctor if your condition persists or worsens.