Drug-drug. Amiodarone, bepridil, disopyramide, erythromycin, pentamidine, phenothiazines, pimozide, procainamide, quinidine, sotalol, tricyclic antidepressants: increased risk of serious adverse cardiovascular reactions
Antacids, bismuth subsalicylate, iron or zinc salts, sucralfate: decreased Gamoflo absorption
Corticosteroids: increased risk of tendon rupture
Probenecid: decreased renal elimination of Gamoflo
Theophylline: increased theophylline blood level and possible toxicity
Warfarin: increased warfarin effects
Drug-diagnostic tests. Alanine aminotransferase, aspartate aminotransferase, platelets: increased levels
Hemoglobin, hematocrit: decreased values
Drug-food. Milk or yogurt (consumed alone), tube feedings: impaired drug absorption
Drug-herbs. Fennel: decreased drug absorption
Dong quai, St. John's wort: phototoxicity
Drug-behaviors. Sun exposure: phototoxicity
Pharmacologic class: Fluoroquinolone
Therapeutic class: Anti-infective
Pregnancy risk category C
As with other anti-infectives, prolonged use may result in overgrowth of non susceptible organisms, including fungi. If super infection occurs discontinue use and institute alternative therapy. Whenever clinical judgment dictates, the patient should be examined with the aid of magnification, such as slit lamp biomicroscopy and, where appropriate, fluorescein staining. Gamoflo should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity reaction.
The systemic administration of quinolones, including Gamoflo, has led to lesions or erosions of the cartilage in weight-bearing joints and other signs of arthropathy in immature animals of various species. Gamoflo, administered systemically at 10 mg/kg/day in young dogs (equivalent to 110 times the maximum recommended daily adult ophthalmic dose) has been associated with these types of effects.
Is Gamoflo safe to take while pregnant or breastfeeding?
Gamoflo should be avoided during pregnancy because it is secreted in breast milk and can cause adverse events in the infant.
Gamoflo should be avoided in nursing mothers, as safe use has not been established.
What Other Drugs Interact with Gamoflo?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Gamoflo has no known severe interactions with other drugs.
Gamoflo has serious interactions with at least 42 different drugs.
Gamoflo has moderate interactions with at least 162 different drugs.
Gamoflo has mild interactions with at least 94 different drugs.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.