What is Fixx, and how does it work (mechanism of action)?
Fixx is a semi-synthetic (partially man-made), oral antibiotic in the cephalosporin family of antibiotics. The cephalosporin family includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefprozil (Cefzil), and many injectable forms. Like other cephalosporins, Fixx stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together; most bacteria cannot survive without a cell wall. Fixx is active against a very wide spectrum of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes (the cause of strep throat), Hemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella, Proteus mirabilis, Salmonella, Shigella, and Neisseria gonorrhoeae. The FDA approved Fixx in April 1989.
Fixx During Pregnancy and Breastfeeding
Fixx has been assigned to pregnancy category B by the FDA. Animal studies failed to reveal evidence of fetal harm. There are no controlled data in human pregnancy. Fixx is only recommended for use during pregnancy when benefit outweighs risk.
There are no data on the excretion of Fixx into human milk. Other cephalosporins are excreted into human milk in small amounts. While adverse effects are unlikely, the infant should be monitored closely.
Generic Name: Fixx (sef IX eem)Brand Name: Suprax
Medically reviewed by Drugs.com on Mar 29, 2019 – Written by Cerner Multum
storage and disposal of Fixx
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets, chewable tablets, and capsules at room temperature and away from excess heat and moisture (not in the bathroom).
Keep liquid medicine at room temperature or in the refrigerator, closed tightly, and dispose of any unused medication after 14 days. .
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
Before taking Fixx,
- tell your doctor and pharmacist if you are allergic to Fixx; other cephalosporin antibiotic such as cefaclor (Ceclor), cefadroxil cefazolin (Ancef, Kefzol), cefdinir, cefditoren (Spectracef), cefepime (Maxipime), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefpodoxime, cefprozil, ceftaroline (Teflaro), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten (Cedax), ceftriaxone (Rocephin), cefuroxime (Zinacef), or cephalexin (Keflex); penicillin antibiotics, or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking, or plant to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven), and carbamazepine (Carbatrol, Epito, Equetro, Tegretol, Teril). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had gastrointestinal disease (GI; affecting the stomach or intestines), especially colitis (condition that causes swelling in the lining of the colon ), or kidney or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking Fixx, call your doctor.
- if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that Fixx chewable tablets are sweetened with aspartame that forms phenylalanine.
What are some other side effects of Fixx Capsules and Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
What are the side effects of Fixx?
Common side effects of Fixx include:
Other side effects include:
Fixx 400 mg orally in a single dose, or ceftriaxone 125 mg IM in a single dose, or ciprofloxacin 500 mg orally in a single dose, or ofloxacin 400 mg orally in a single dose, or levofloxacin 250 mg orally in a single dose, plus, if chlamydial infection is not ruled out azithromycin 1 gm orally in a single dose or doxycycline 100 mg orally twice a day for 7 days.
Quinolones should not be used for infections acquired in Asia or the Pacific, including Hawaii. In addition, use of quinolones is inadvisable for treating infections acquired in California and in other areas with increased prevalence of quinolone resistance.
Generic Name: Fixx Capsules and Tablets (sef IKS eem)Brand Name: Suprax
Medically reviewed by Drugs.com. Last updated on Aug 18, 2019.
Hello Lalainuk. I'd say yes. But I'd leave it at one glass. As you know Fixx is an antibiotic, and as a rule antibiotics and alcohol are not mixed. When alcohol is consumned along with Fixx, it weakens the drug, in as much as it (Fixx) leaves your body earlier than intended. So, its not receiving the full theraputic effects of the drug. Thats why I suggested only the one glass. But, I'm not a doctor, so I'd check with your doctor or pharmacist to confirm or get thier opinion.very best to you
Fixx S >
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe stomach pain, diarrhea that is watery or bloody;
- jaundice (yellowing of the skin or eyes);
- pale or yellowed skin, dark colored urine, confusion or weakness;
- a seizure (convulsions);
- low blood cell counts--sudden weakness or ill feeling, fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling light-headed;
- kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
- severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
- indigestion, stomach pain;
- nausea, vomiting; or
- vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.