What is Exocin?
Exocin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body.
Exocin is used to treat bacterial infections of the skin, lungs, prostate, or urinary tract (bladder and kidneys). Exocin is also used to treat pelvic inflammatory disease and Chlamydia and/or gonorrhea.
Fluoroquinolone antibiotics can cause serious or disabling side effects that may not be reversible. Exocin should be used only for infections that cannot be treated with a safer antibiotic.
Exocin may also be used for purposes not listed in this medication guide.
Additional studies in rats with doses up to 360 mg/kg/day during late gestation showed no adverse effect on late fetal development, labor, delivery, lactation, neonatal viability, or growth of the newborn. There are, however, no adequate and well-controlled studies in pregnant women. Exocin ophthalmic solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
How should this medicine be used?
Ophthalmic Exocin comes as an solution (liquid) to instill in the eye. It is usually instilled in the affected eye(s) four or more times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Exocin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
As with other anti-infectives, prolonged use may result in overgrowth of non susceptible organisms, including fungi. If super infection occurs discontinue use and institute alternative therapy. Whenever clinical judgment dictates, the patient should be examined with the aid of magnification, such as slit lamp biomicroscopy and, where appropriate, fluorescein staining. Exocin should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity reaction.
The systemic administration of quinolones, including Exocin, has led to lesions or erosions of the cartilage in weight-bearing joints and other signs of arthropathy in immature animals of various species. Exocin, administered systemically at 10 mg/kg/day in young dogs (equivalent to 110 times the maximum recommended daily adult ophthalmic dose) has been associated with these types of effects.
Common Side Effects of Exocin
Oral form: Tell your doctor if any of the following side effects of become severe or don't go away:
- Nausea, mild diarrhea, constipation, gas, or vomiting
- Stomach pain or cramps
- Loss of appetite
- Change in ability to taste food
- Dry mouth
- Excessive tiredness
- Pain, swelling, or itching of the vagina
Ear drops: Tell your doctor know if any of the following side effects become severe or don't go away:
- Ear pain or itching
- Changes in taste
Eye drops: Tell your doctor if any of the following side effects become severe or don't go away:
- Blurred vision
- Burning, itching, stinging, redness, or discomfort in the eye
- Dry eyes, eye pain, or tearing
- Sensitivity to sunlight
Which drugs or supplements interact with Exocin?
Exocin reduces the elimination of theophylline, elevating blood levels of theophylline. (Theophylline is used to open airways in the treatment of asthma.) If concurrent use of Exocin and theophylline cannot be avoided, frequent blood tests to monitor theophylline blood levels should be performed. Exocin can enhance the action of the anticoagulant (blood thinner) warfarin (Coumadin), and increase the risk of bleeding. Both high and low blood sugar levels have been reported, especially in patients with diabetes who were also receiving insulin or other medications used to lower the blood sugar. Careful monitoring of blood sugar levels is recommended. Sucralfate (Carafate), iron, multivitamins containing zinc, didanosine (Videx), as well as antacids containing calcium, magnesium, or aluminum should not be taken within two hours before or after taking Exocin.
Michael Stewart, Reviewed by Sid Dajani | Last edited 18 May 2017 | Certified by The Information Standard
Exocin drops are used to treat bacterial eye infections.
Your vision may become slightly blurred for a short while after using the drops. If so, do not drive or use tools or machines until you can see clearly again.
After your symptoms have gone, continue to use the drops for a further 48 hours to make sure all the infection has cleared.
Exocin eye drops are used to treat bacterial eye infections. They work by helping to kill the bacteria which are causing the infection.
Exocin ophthalmic solution is indicated for the treatment of infections caused by susceptible strains of the following bacteria in the conditions listed below:
Avoid contaminating the applicator tip with material from the eye, fingers or other source.
Systemic quinolones, including Exocin, have been associated with hypersensitivity reactions, even following a single dose. Discontinue use immediately and contact your physician at the first sign of a rash or allergic reaction.
Getting the most from your treatment
- Before you start the treatment, read the manufacturer's printed information leaflet from the pack. The manufacturer's leaflet will give you more information about the drops, and a full list of side-effects which you may experience from using them.
- If your eyes have an obvious discharge or 'crust', it can help if you bathe them with cool clean water before using Exocin.
- Use the drops regularly, exactly as your doctor tells you to. If the infection is severe, this is likely to be every 2-4 hours for the first two days. (Just use the drops while you are awake - you do not need to wake yourself up during the night to put them in.) On day three, reduce the frequency down to four times a day.
- If your symptoms do not improve within a few days, or if they become worse, speak again with your doctor.
- When you first put the drops into your eye, it may cause blurred vision. This should quickly clear, but make sure you can see clearly again before you drive or use machines or tools.
- Take care to avoid spreading the infection from one eye to the other, and to other members of your family. Washing your hands regularly (particularly after touching your eyes), and not sharing towels or pillows will help to prevent the infection from spreading.
- If the tip of the bottle touches your eye(s) when putting the drops in, it is a good idea to squeeze out two or three drops straightaway on to some tissue and rinse the tip with salt water.
- Eye infections, or using Exocin eye drops, may cause your eyes to become more sensitive to sunlight than usual. Wearing sunglasses may help to protect your eyes.
- If you are using any other eye drops, leave at least five minutes between applying each preparation. This is to prevent more liquid going into your eye than it can handle. Otherwise the drops will overflow from your eye and not have the intended effect.
- Even when your eye appears normal again, there may still be some bacteria present. It is important to continue to use the drops for a further 48 hours once your eye appears normal. This will help to make sure that all the bacteria have been killed. It is likely that you may need to use the drops for about a week, but you should not use them for any longer than 10 days.
- Do not wear contact lenses until your symptoms have completely gone. Wait for 24 hours after the last dose of eye drops before using your lenses again.
How to store Exocin eye drops
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
- Throw away the bottle after you have finished the course of treatment, even if there is some liqu >
The drops are for use in the eyes only. If someone swallows some, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are using.
If you buy any medicines check with a pharmacist that they are suitable to take with your other medicines.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
What are some things I need to know or do while I take Exocin?
- Tell all of your health care providers that you take Exocin (ophthalmic). This includes your doctors, nurses, pharmacists, and dentists.
- Use care when driving or doing other tasks that call for clear eyesight.
- Bright lights may bother you. Wear sunglasses.
- Do not use longer than you have been told. A second infection may happen.
- Very bad and sometimes deadly allergic reactions have rarely happened with other forms of Exocin (ophthalmic) as well as drugs like this one. Talk with the doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Exocin (ophthalmic) while you are pregnant.
What is the dosage for Exocin?
- The usual dose for patients with normal renal function is 200 to 400 mg every 12 hours.
- Dosages require adjustment in patients with severely abnormal liver or kidney function.
- Oflaxacin is available as tablets: 200, 300, and 400mg.
- Exocin should be stored in a closed container at 15 C - 30 C (59 F - 86 F).