Ethiflox

Ethiflox

  • Active Ingredient: Ofloxacin
  • 400 mg, 200 mg
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What is Ethiflox?

The active ingredient of Ethiflox brand is ofloxacin. Ofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Ofloxacin, USP is an off-white to pale yellow crystalline powder. The molecule exists as a zwitterion at the pH conditions in the small intestine. The relative solubility characteristics of Ofloxacin, USP at room temperature, as defined by USP nomenclature, indicate that Ofloxacin, USP is considered to be soluble in aqueous solutions with pH between 2 and 5. It is sparingly to slightly soluble in aqueous solutions with pH 7 (solubility falls to 4 mg/mL) and freely soluble in aqueous solutions with pH above 9. Ofloxacin, USP has the potential to form stable coordination compounds with many metal ions. This in vitro chelation potential has the following formation order: Fe +3 > Al +3 > Cu +2 > Ni +2 > Pb +2 > Zn +2 > Mg +2 > Ca +2 > Ba +2.

Used for

Ethiflox is used to treat diseases such as: Anthrax, Anthrax Prophylaxis, Bladder Infection, Bone infection, Bronchitis, Campylobacter Gastroenteritis, Cervicitis, Chancroid, Chlamydia Infection, Epididymitis, Non-Specific, Epididymitis, Sexually Transmitted, Gonococcal Infection, Disseminated, Gonococcal Infection, Uncomplicated, Joint Infection, Kidney Infections, Methicillin-Resistant Staphylococcus Aureus Infection, Mycobacterium avium-intracellulare, Treatment, Nongonococcal Urethritis, Pelvic Inflammatory Disease, Plague, Pneumonia, Prostatitis, Salmonella Enteric Fever, Salmonella Gastroenteritis, Shigellosis, Skin or Soft Tissue Infection, Traveler's Diarrhea, Tuberculosis, Active, Urinary Tract Infection.

Side Effect

Possible side effects of Ethiflox include: itching of the vagina or outside the genitals; burning, dry, or itching eyes; discouragement; increased urination; redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid; cough; darkening of the skin; Change in taste.

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Getting the most from your treatment

  • Before you start the treatment, read the manufacturer's printed information leaflet from the pack. The manufacturer's leaflet will give you more information about the drops, and a full list of side-effects which you may experience from using them.
  • If your eyes have an obvious discharge or 'crust', it can help if you bathe them with cool clean water before using Ethiflox.
  • Use the drops regularly, exactly as your doctor tells you to. If the infection is severe, this is likely to be every 2-4 hours for the first two days. (Just use the drops while you are awake - you do not need to wake yourself up during the night to put them in.) On day three, reduce the frequency down to four times a day.
  • If your symptoms do not improve within a few days, or if they become worse, speak again with your doctor.
  • When you first put the drops into your eye, it may cause blurred vision. This should quickly clear, but make sure you can see clearly again before you drive or use machines or tools.
  • Take care to avoid spreading the infection from one eye to the other, and to other members of your family. Washing your hands regularly (particularly after touching your eyes), and not sharing towels or pillows will help to prevent the infection from spreading.
  • If the tip of the bottle touches your eye(s) when putting the drops in, it is a good idea to squeeze out two or three drops straightaway on to some tissue and rinse the tip with salt water.
  • Eye infections, or using Ethiflox eye drops, may cause your eyes to become more sensitive to sunlight than usual. Wearing sunglasses may help to protect your eyes.
  • If you are using any other eye drops, leave at least five minutes between applying each preparation. This is to prevent more liquid going into your eye than it can handle. Otherwise the drops will overflow from your eye and not have the intended effect.
  • Even when your eye appears normal again, there may still be some bacteria present. It is important to continue to use the drops for a further 48 hours once your eye appears normal. This will help to make sure that all the bacteria have been killed. It is likely that you may need to use the drops for about a week, but you should not use them for any longer than 10 days.
  • Do not wear contact lenses until your symptoms have completely gone. Wait for 24 hours after the last dose of eye drops before using your lenses again.

Ethiflox Ophthalmic S >

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe burning, stinging, or irritation after using this medicine;
  • eye pain;
  • eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection); or
  • severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • blurred vision;
  • eye pain or
  • mild burning, stinging, or other discomfort;
  • eye redness, itching, or watering;
  • red or puffy eyelids;
  • your eyes being more sensitive to light; or
  • eye dryness, feeling like something is in your eye.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pediatric Use

Safety and effectiveness in infants below the age of one year have not been established. Quinolones, including Ethiflox, have been shown to cause arthropathy in immature animals after oral administration; however, topical ocular administration of Ethiflox to immature animals has not shown any arthropathy. There is no evidence that the ophthalmic dosage form of Ethiflox has any effect on weight bearing joints.

Ethiflox Ophthalmic Interactions

Avoid wearing contact lenses until you no longer have symptoms of the eye infection.

This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Do not use other eye medications unless your doctor tells you to.

It is not likely that other drugs you take orally or inject will have an effect on Ethiflox used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Ethiflox?"

Pregnancy and Ethiflox

It's not known whether Ethiflox can harm an unborn baby.

Tell your doctor if you're pregnant, or might become pregnant, before taking this medicine.

It's also not known whether this drug can harm a breastfeeding baby. Don't breastfeed while taking Ethiflox.

What are some other side effects of Ethiflox?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Pregnancy Category C: Ethiflox has been shown to have an embryocidal effect in rats and in rabbits when given in doses of 810 mg/kg/day (equivalent to 9000 times the maximum recommended daily ophthalmic dose) and 160 mg/kg/day (equivalent to 1800 times the maximum recommended daily ophthalmic dose).

These dosages resulted in decreased fetal body weight and increased fetal mortality in rats and rabbits, respectively. Minor fetal skeletal variations were reported in rats receiving doses of 810 mg/kg/day. Ethiflox has not been shown to be teratogenic at doses as high as 810 mg/kg/day and 160 mg/kg/day when administered to pregnant rats and rabbits, respectively.

Michael Stewart, Reviewed by Sid Dajani | Last edited 18 May 2017 | Certified by The Information Standard

Ethiflox drops are used to treat bacterial eye infections.

Your vision may become slightly blurred for a short while after using the drops. If so, do not drive or use tools or machines until you can see clearly again.

After your symptoms have gone, continue to use the drops for a further 48 hours to make sure all the infection has cleared.

Important Information

Ethiflox can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar.

Stop using Ethiflox and call your doctor at once if you have symptoms such as: headache, hunger, irritability, numbness, tingling, burning pain, confusion, agitation, paranoia, problems with memory or concentration, thoughts of suicide, or sudden pain or movement problems in any of your joints.

In rare cases, Ethiflox may cause damage to your aorta, which could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.


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