E-Glades ointment


  • Active Ingredient: Erythromycin
  • 500 mg, 250 mg
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What is E-Glades?

The active ingredient of E-Glades brand is erythromycin. Erythromycin is a macrolide antibiotic. Erythromycin fights bacteria in the body.

Used for

E-Glades is used to treat diseases such as: Bacterial Endocarditis Prevention, Bartonellosis, Bowel Preparation, Bronchitis, Bullous Pemphigoid, Campylobacter Gastroenteritis, Chancroid, Chlamydia Infection, Dental Abscess, Legionella Pneumonia, Lyme Disease, Lymphogranuloma Venereum, Mycoplasma Pneumonia, Nongonococcal Urethritis, Ocular Rosacea, Otitis Media, Pemphigoid, Pertussis, Pharyngitis, Pneumonia, Rheumatic Fever Prophylaxis, Skin or Soft Tissue Infection, Strep Throat, Syphilis, Early, Upper Respiratory Tract Infection.

Side Effect

Possible side effects of E-Glades include: diarrhea; Abdominal or stomach cramps or tenderness; Blistering, peeling, or loosening of the skin; bloating; tightness in the chest; sore throat.

How to Buy E-Glades ointment online?

To purchase E-Glades online - just click on the "Buy Now" button from the top and follow on to our store. Order and payment takes a couple of minutes, and all measures are obvious. We don't require a medical prescription and we have many procedures of payment. Considering each detail of fast shipping and confidentiality, you may read on the applicable pages on the hyperlinks in the top menu.

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Diphtheria is a disease that causes symptoms and signs such as fever, enlarged lymph nodes, and swallowing problems. E-Glades is the primary treatment for diphtheria. Vaccines that prevent diphtheria include the DTaP, Tdap, DT, and Td.

1. About E-Glades

E-Glades is an antibiotic.

E-Glades is used in children, often to treat ear infections or chest infections.

The medicine is available on prescription as tablets, capsules, or a liquid that you drink.

It's also available as a skin solution to treat skin infections like acne. It can be given by injection, but this is usually only done in hospital.

Drug interactions with E-Glades

E-Glades has important interactions with other medications. Tell your doctor the names of all medications you are taking, whether prescribed or purchased without a prescription.

  • E-Glades should not be taken with terfenadine, astemizole or cisapride because it could result in dangerous irregularities of the heartbeat and sudden death. These drugs are no longer available in New Zealand.
  • Other drugs that can prolong the Q-T interval include amiodarone, risperidone, haloperidol, citalopram and ciprofloxacin.

E-Glades can increase the concentration of the following medications resulting in potentially toxic levels.

  • Warfarin (additional prothrombin time blood tests are necessary)
  • Statins, particularly simvastatin and atorvastatin. Toxicity results in muscle pain and weakness, which may be serious. If long-term treatment with a statin and E-Glades is required, suitable alternatives are fluvastatin, pravastatin and rosuvastatin.
  • Caffeine
  • Theophylline
  • Carbamazepine
  • Ciclosporin
  • Ergotamine (increases peripheral ischaemia )
  • Digoxin
  • Triazolam
  • M >New Zealand approved datasheets are the official source of information for these prescription medicines, including approved uses and risk information. Check the individual New Zealand datasheet on the Medsafe website.

How to use E-Glades Ointment

To apply eye ointment, wash your hands first. To avoid contamination, be careful not to touch the tip of the tube or let it touch your eye, eyelid, or any other surface. Apply to the eyes only. Do not swallow or inject.

Do not wear contact lenses while you are using this medication. Sterilize contact lenses according to the manufacturer's directions, and check with your doctor before you begin using them again.

To apply eye ointments, tilt your head back, look up, and gently pull down the lower eyelid to make a pouch. Place about a half-inch (1 centimeter) strip of ointment into the pouch as directed by your doctor. Gently close the eye and roll the eyeball in all directions to spread the medication. Try not to blink and do not rub the eye. Repeat these steps for your other eye if so directed. Wipe the tip of the ointment tube with a clean tissue to remove extra medication before recapping it. Wait several minutes for your vision to clear before driving or operating machinery.

The dosage is based on your medical condition and response to treatment. Do not increase your dose or use it more often than directed.

If you are using another kind of eye medication (such as drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the drops to enter the eye.

Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. Continue using it for the full time prescribed. Stopping the medication too soon may allow the bacteria to continue to grow, which may result in a return of the infection.

Tell your doctor if your condition persists or worsens.

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References updated: 10 August 2017

50%] as well as eosinophilia , elevations in ALT and Alk P ; 13 rechallenged, invariably followed by rapid recurrence, often severe])

3 weeks; lymphocyte transformation tests was positive 2 years later to estolate but not stearate or E-Glades base).

5000 physicians using E-Glades in UK during 2 months of 1982, 3 reports of jaundice attributable to drug, all due to E-Glades stearate).

15% after the courses, usually mild and transient; only 3 attributed to drug).

E-Glades Ophthalmic Interactions

This medicine may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

Do not use other eye medications unless your doctor tells you to.

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Which drugs or supplements interact with E-Glades?

E-Glades when used with antiarrhythmic drugs such as, amiodarone (Cordarone), bretylium (Bretylol), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Pronestyl), quinidine (Quinaglute, Quinidex, Quinora) and sotalol (Betapace) exaggerates the effect of the antiarrhythmic drugs which may give rise to abnormal heart rhythms such as torsades de pointes.

Theophyllines such as theophylline (Theo-Dur), oxtriphylline (Choledyl SA), and aminophylline (Phyllocontin) reduce E-Glades blood levels by increasing elimination of E-Glades by the kidneys, which may reduce the effectiveness of E-Glades. Conversely, E-Glades inhibits the metabolism (breakdown) of theophyllines by the liver and causes an increase in blood levels of theophylline. High theophylline levels may give rise to side effects such as seizures and disturbances in heart rhythm. Therefore, the dose of theophyllines should be reduced or theophylline levels in the blood should be measured in patients taking E-Glades.

Combining E-Glades with ergotamine or ydroergotamine has been associated with acute ergot toxicity. This combination should be avoided.

E-Glades prevents digoxin (Lanoxin) from being eliminated by the kidneys; this in turn causes increased levels of digoxin in the blood. Increased levels of digoxin can cause disturbances in heart rhythm. Therefore, it is important to monitor and adjust digoxin doses when treating with E-Glades.

E-Glades prevents the elimination of warfarin (Coumadin) from the body which can raise the levels of warfarin in the blood. Warfarin is an anticoagulant or blood thinner, and an increase in its level in blood can increase the risk of bleeding. It is important to monitor the effects of warfarin and adjust warfarin doses when treating with E-Glades.

E-Glades inhibits the breakdown of HMG-CoA reductase inhibitors (statins) such as atorvastatin (Lipitor), lovastatin (Mevacor) and simvastatin (Zocor) by the liver leading to increased levels of statins in the blood. High levels of statins could result in severe myopathy (muscle damage) with rhabdomyolysis (r (rapid breakdown of skeletal muscle) that may damage the kidneys or even lead to death. E-Glades also can elevate blood levels of some anti-seizure drugs such as carbamazepine (Tegretol) by preventing the breakdown of the anti-seizure drug by the liver. Therefore, doses of the anti-seizure drugs may need to be reduced during treatment with E-Glades. E-Glades also increases blood levels of sildenafil (Viagra). The dose of sildenafil should be reduced when treating with E-Glades.

Grapefruit juice may prevent the breakdown of E-Glades, resulting in elevated levels of E-Glades in the blood. Therefore, it is important to avoid eating grapefruit or drinking grapefruit juice during treatment with E-Glades.

What are the side effects of E-Glades?

The most frequent side effects of E-Glades are

These gastrointestinal side effects are usually dose-related, i.e., more pronounced with higher doses.

Allergic reactions such as


E-Glades and other macrolides inhibit bacterial protein synthesis and are bacteriostatic. Macrolides are primarily applied in the treatment of infections with Gram-positive germs, but are also effective against Haemophilus influenzae and intracellular pathogens such as chlamydia. Macrolides offer an alternative for patients with penicillin allergy.

E-Glades is the oldest medication of this group. Its resorption can be delayed in the third trimester. Gastrointestinal side effects can lead to lower than therapeutic plasma concentrations, resulting in treatment failure ( Larsen 1998 ). Only 5–20% of the maternal E-Glades concentration is obtained in the fetus. Therefore, E-Glades is not a sufficiently reliable drug for fetal or amniotic infections.

The newer macrolide antibiotics azithromycin, clarithromycin, dirithromycin, josamycin, midecamycin, roxithromycin and troleandomycin have a similar antibacterial spectrum as E-Glades, but to some degree less gastrointestinal side effects. Spiramycin is used for toxoplasmosis in the first trimester.

Telithromycin is the first ketolide antibiotic for clinical use. It is structurally related to E-Glades.


Before using E-Glades, tell your doctor or pharmacist if you are allergic to it; or to other macrolide antibiotics (such as clarithromycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.

After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether E-Glades passes into breast milk when given as an eye ointment. It is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

What other drugs will affect E-Glades?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can interact with E-Glades, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

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What Is E-Glades Ophthalmic?

E-Glades is an antibiotic that fights bacteria.

E-Glades ophthalmic (for the eyes) is used to treat bacterial infections of the eyes.

E-Glades ophthalmic may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

You should not use this medicine if you are allergic to E-Glades.

  • a viral or fungal infection in your eye.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

E-Glades Ophthalmic S >

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using E-Glades ophthalmic and call your doctor at once if you have:

  • severe burning, stinging, or irritation after using this medicine; or
  • signs of eye infection--pain, swelling, severe discomfort, crusting or drainage, eyes more sensitive to light.

Common side effects may include:

  • eye redness; or
  • mild eye irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Before taking E-Glades, tell your doctor or pharmacist if you are allergic to it; or to other macrolide antibiotics (such as azithromycin, clarithromycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, a certain type of muscle disease (myasthenia gravis).

E-Glades may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using E-Glades, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using E-Glades safely.

E-Glades may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Some E-Glades products may contain sodium. Ask your doctor or pharmacist for more information if you are on a salt-restricted diet or if you have a condition such as congestive heart failure that could be worsened by an increase in salt intake.

Older adults may be more sensitive to the side effects of this drug, especially hearing loss and QT prolongation (see above).

Tell your doctor if you are pregnant before using this medication.

This medication passes into breast milk. Consult your doctor before breast-feeding.

E-Glades Dosage

E-Glades is available in many different dosage forms including cream, gel, tablet, and solution for injection into the veins.

Depending on the condition, doses of E-Glades tend to range from the following:

  • 250 milligrams (mg) to 500 mg, every six to 12 hours
  • 500 mg every 12 hours
  • 333 mg every eight hours

When taking tablets, be sure to take the medication exactly as your doctor or pharmacist directed.

Be sure to finish the entire prescription - even if you start to feel better or your symptoms subside. Otherwise, the infection could come back and might be much more difficult to treat.

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