Q: Is there a remedy for the reaction I am having to Clindamicin? I am using Lanacaine and CVS's Instant Relief Spray to no avail.
A: Cleocin (Clindamicin) is an antibiotic that is used to treat a variety of infections. If you have a reaction to Clindamicin which causes rash, it can be treated with Benadryl (diphenhydramine) which will help to reduce some of the itching. If the reaction consists of difficulty breathing, stop using the Clindamicin and contact your physician as soon as possible. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Megan Uehara, PharmD
Clostridium perfringens Fusobacterium necrophorum Fusobacterium nucleatum Peptostreptococcus anaerobius Prevotella melaninogenica
At least 90% of the microorganisms listed below exhibit in vitro minimum inhibitory concentrations (MICs) less than or equal to the Clindamicin susceptible MIC breakpoint for organisms of a similar type to those shown in Table 1. However, the efficacy of Clindamicin in treating clinical infections due to these microorganisms has not been established in adequate and well-controlled clinical trials.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Antibiotic-associated diarrhea. Symptoms can include:
- severe diarrhea
- bloody diarrhea
- stomach cramping and pain
- loss of appetite
- weight loss
- severe rash
- peeling skin
- swollen face or tongue
- blisters on your skin or blisters in or around your nose, mouth, and eyes
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Clindamicin oral capsule can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
The antibiotics erythromycin and Clindamicin can decrease each other’s effectiveness. They shouldn’t be taken at the same time .
Significant mortality was observed in mice at an intravenous dose of 855 mg/kg and in rats at an oral or subcutaneous dose of approximately 2618 mg/kg. In the mice, convulsions and depression were observed.
Hemodialysis and peritoneal dialysis are not effective in removing Clindamicin from the serum.
Some antibiotics are known to reduce the effectiveness of birth control pills . The effect of Clindamicin on birth control has not been studied. However, it would be wise to use additional contraceptive measures while on this antibiotic .
What should I avoid while using Clindamicin?
Do not use Clindamicin at the same time as the antibiotic, erythromycin.