What should I discuss with my veterinarian before giving CIPROFAT to my pet?
Tell your veterinarian if your pet has had epilepsy or seizures, or has joint problems or kidney disease. Tell your veterinarian if your pet is pregnant or lactating.
Some drugs may affect the way CIPROFAT works, and CIPROFAT may affect other drugs you are taking.
It's very important to let your doctor know about all drugs you take, including over-the-counter (OTC) antacids, vitamins, and supplements.
Many antacids, vitamins, and supplements that contain magnesium, calcium, aluminum, iron, or zinc can interfere with CIPROFAT.
Other OTC drugs, including such pain and fever medications as Advil, Aleve, and Motrin, may also interact with CIPROFAT.
CIPROFAT may increase the effects of caffeine.
If you drink caffeinated drinks or take OTC medications that contain caffeine while taking CIPROFAT, you may have some caffeine side effects such as nervousness, sleeplessness, or anxiety.
You may not be able to take CIPROFAT if you are also taking the drug theophylline to treat asthma and wheezing (brand names include Elixophyllin, Uniphyl, and Theo-24).
Serious reactions, including heart attack, decreased ability to breathe, and seizures, have happened when people took these medications together.
Other medications that interact with CIPROFAT include:
- Blood thinners, such as warfarin (Coumadin, Jantoven)
- Anti-seizure medication, including phenytoin (Dilantin, Phenytek)
- Certain antidepressants and medications to treat mental illness, such as clozapine (Clozaril, FazaClo)
- Medications that contain caffeine, including Excedrin, NoDoz, and Vivarin
- The immunosuppressant cyclosporine (Gengraf, Neoral, Sandimmune)
- The muscle relaxant tizanidine (Zanaflex)
- Diuretics (water pills)
- Certain drugs for irregular heartbeat, such as amiodarone (Cordarone), disopyramide (Norpace), and procainamide (Procanbid)
- The arthritis drug methotrexate (Rheumatrex, Trexall)
- A drug used to treat nausea, vomiting, heartburn, and reflux called metoclopramide (Reglan)
- The type 2 diabetes drug glyburide (DiaBeta, Glucovance, Micronase)
- Some non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn)
Rated CIPROFAT (Cipro) for Diverticulitis Report
Cipro is rough on a body. I’ve taken different types of antibiotics for different medical reasons, but Cipro is by far the worst reaction I have ever had to a drug. It has drained me of energy, made me very light headed, left me tasting metallic, loss of appetite, sleepy, headaches and just plain feeling lousy. I stopped taking it after 4 days into a 7 day prescription. Awful stuff. Read the side affects and you may not take it at all.
By Chris Iliades, MD | Medically Reviewed by Farrokh Sohrabi, MD
Latest Update: 2014-07-30 Copyright © 2014 Everyday Health Media, LLC
What Are Side Effects Associated with Using CIPROFAT?
Common Side effects of CIPROFAT include:
Less common side effects of CIPROFAT include:
Side effects of CIPROFAT from postmarketing reports include:
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
What drugs interact with Cipro (CIPROFAT)?
CIPROFAT is an inhibitor of human cytochrome P450 1A2 (CYP1A2) mediated metabolism. Co-administration of CIPRO XR with other drugs primarily metabolized by CYP1A2 results in increased plasma concentrations of these drugs and could lead to clinically significant adverse events of the co-administered drug.
Adverse Laboratory Changes
Changes in laboratory parameters while on CIPRO are listed below:
Hepatic – Elevations of ALT (SGPT), AST (SGOT), alkaline phosphatase, LDH, serum bilirubin.
Hematologic – Eosinophilia, leukopenia, decreased blood platelets, elevated blood platelets, pancytopenia.
Renal – Elevations of serum creatinine, BUN, crystalluria, cylindruria, and hematuria have been reported.
Other changes occurring were: elevation of serum gammaglutamyl transferase, elevation of serum amylase, reduction in blood glucose, elevated uric acid, decrease in hemoglobin, anemia, bleeding diathesis, increase in blood monocytes, and leukocytosis.
Read the entire FDA prescribing information for Cipro (CIPROFAT)
Can CIPROFAT cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with CIPROFAT. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
What should I avoid while giving CIPROFAT to my pet?
Do not administer CIPROFAT to pregnant pets, as it has detrimental effects on growing joints and bones. Do not give CIPROFAT to pets younger than 1 year of age. It may also have a detrimental effect on growing large breed dogs as old as 2 years. Use with extreme caution on cats, especially those with pre-existing kidney failure. Use with caution in all pets with kidney disease, liver disease, central nervous system disorders, or epilepsy.