Cifran tablets

Cifran

  • Active Ingredient: Ciprofloxacin
  • 1000 mg, 750 mg, 500 mg, 250 mg
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What is Cifran?

The active ingredient of Cifran brand is ciprofloxacin. Ciprofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Ciprofloxacin is used to treat different types of bacterial infections. Ciprofloxacin is also used to treat people who have been exposed to anthrax or certain types of plague. Ciprofloxacin film-coated Tablets are available in 250 mg, 500 mg and 750 mg (Ciprofloxacin equivalent) strengths. Ciprofloxacin tablets USP are white to slightly yellowish. The inactive ingredients are pregelatinized starch, microcrystalline cellulose, colloidal silicon dioxide, crospovidone, magnesium stearate, hypromellose, titanium dioxide, polyethylene glycol, and purified water.

Used for

Cifran is used to treat diseases such as: Anthrax, Anthrax Prophylaxis, Bacteremia, Bacterial Infection, Bladder Infection, Bone infection, Bronchiectasis, Bronchitis, Chancroid, Cholera, Crohn's Disease, Cutaneous Bacillus anthracis, Diverticulitis, Epididymitis, Sexually Transmitted, Febrile Neutropenia, Gonococcal Infection, Disseminated, Gonococcal Infection, Uncomplicated, Granuloma Inguinale, Infection Prophylaxis, Infectious Diarrhea, Intraabdominal Infection, Joint Infection, Kidney Infections, Meningococcal Meningitis Prophylaxis, Mycobacterium avium-intracellulare, Treatment, Nosocomial Pneumonia, Peritonitis, Plague, Plague Prophylaxis, Pneumonia, Pneumonia with Cystic Fibrosis, Pouchitis, Prostatitis, Rabbit Fever, Salmonella Enteric Fever, Salmonella Gastroenteritis, Shigellosis, Sinusitis, Skin and Structure Infection, Skin or Soft Tissue Infection, Surgical Prophylaxis, Traveler's Diarrhea, Tuberculosis, Active, Typhoid Fever, Urinary Tract Infection.

Side Effect

Possible side effects of Cifran include: dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position; confusion; Bloody or black, tarry stools; Acid or sour stomach; chills or fever; hearing loss; numbness of the hands; clumsiness or unsteadiness.

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COMMON BRAND(S): Cipro

GENERIC NAME(S): Cifran

OTHER NAME(S): Cifran Suspension, Microcapsule Reconstituted

Quinolone antibiotics (including Cifran) may cause serious and possibly permanent tendon damage (such as tendonitis, tendon rupture), nerve problems in the arms and legs (peripheral neuropathy), and nervous system problems. Get medical help right away if you have any of the following symptoms: pain/numbness/burning/tingling/weakness in your arms/hands/legs/feet, changes in how you sense touch/pain/temperature/vibration/body position, severe/lasting headache, vision changes, shaking (tremors), seizures, mental/mood changes (such as agitation, anxiety, confusion, hallucinations, depression, rare thoughts of suicide).

Tendon damage may occur during or after treatment with this medication. Stop exercising, rest, and get medical help right away if you develop joint/muscle/tendon pain or swelling. Your risk for tendon problems is greater if you are over 60 years of age, if you are taking corticosteroids (such as prednisone), or if you have a kidney, heart, or lung transplant.

This medication may make a certain muscle condition (myasthenia gravis) worse. Tell your doctor right away if you have new or worsening muscle weakness (such as drooping eyelids, unsteady walk) or trouble breathing.

Discuss the risks and benefits with your doctor before using this medication.

This medication is used to treat a variety of bacterial infections. Cifran belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. It will not work for virus infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

What else should I know about Cirpo?

  • Storage of Cirpo:
    • Tablets should be stored below 30 C (86 F).
    • Extended release tablets should be stored between 15 C to 30 C (59 F to 86 F).
    • Microcapsules should be stored below 25 C (77 F) and protected from freezing. Injections should be stored between 5 C to 30 C (41 F to 86 F) and prevented from freezing.
  • You need a prescription for Cipro from you doctor or other healthcare professional.
  • Cifran is the generic name for Cipro and Cipro XR.
  • Cipro is available in generic form.

Generic Name: Cifran (oral) (SIP roe FLOX a sin)Brand Names: Cipro, Cipro XR, Proquin XR

Medically reviewed by Kaci Durbin, MD Last updated on Dec 13, 2018.

Rated Cifran (Cipro) for Diverticulitis Report

I was prescribed Metronidazole AND Cifran 500mg each. Next time my diverticulitis flares up, I'm going on a garlic soup diet or something other than pharmaceuticals. Cause Damn. Side effects of taking both these drugs together. dizzy, diarrhea, stoned (but not fun), found out that Metronidazole is actually a carcinogen and Cifran destroys your tendons. Look it up. I'm only 2 days in on a 10 day prescription, which I'll cut to 5-7 days since I've seen that's been prescribed elsewhere. Just hoping there's no permanent damage done after taking these drugs.

Getting the most from your treatment

  • Remember to keep any routine appointments with your doctor. This is so your progress can be monitored.
  • Cifran may cause your skin to become more sensitive to sunlight than normal. Protect your skin by using a sunscreen, particularly if you are exposed to strong sunlight for a prolonged period of time. Do not use sunbeds.
  • If you buy any medicines, check with a pharmacist that they are safe to take with this antibiotic. In particular, do not take painkillers called non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, while you are taking Cifran.
  • Some people develop thrush (redness and itching in the mouth or vagina) after taking a course of antibiotics. If you think you have thrush, speak with your doctor or pharmacist for advice.
  • This antibiotic may stop the oral typhoid vaccine from working. If you are due to have any vaccinations, make sure the person treating you knows that you are taking this medicine.
  • Cifran may make you feel light-headed and impair your ability to concentrate. Make sure your reactions are normal before you drive and before you use tools or machines.
  • If you have diabetes, you may need to check your blood glucose levels more regularly, as Cifran can affect the levels of sugar in your blood.

Rated Cifran (Cipro) for Ep >Report

I took Cifran 250 mg, twice daily, prescribed for 7 days. about 4 pills in i started noticing joint inflammation/ pain, neck pain, swollen neck lymph nodes, and had terrible, crippling anxiety. i couldn’t even go to class (i’m in college) without having an anxiety issue. I am 5 days off of cipro and still experiencing these issues. hoping to see some relief soon.

Cifran (Cipro) is more effective than amoxicillin-clavulanate (Augmentin) as a treatment for bladder infections in women, even when the microbe is susceptible to the latter drug, according to a report in the Journal of the American Medical Association.

Currently, the standard treatment for bladder infections or cystitis is trimethoprim-sulfamethoxazole (Bactrim), but emerging resistance to this agent has led to greater use of “fluoroquinolone” drugs, such as Cifran. In an effort to maintain the usefulness of this drug class, however, there has been a push to use non-fluoroquinolone antibiotics.

Despite increasing use of amoxicillin-clavulanate for cystitis, few studies have assessed the effectiveness of this treatment, according to Dr. Thomas M. Hooton of Harborview Medical Center in Seattle, and colleagues.

To investigate, the researchers assessed cure rates in 370 women with cystitis who were randomly selected to receive a 3-day course of Cifran or amoxicillin-clavulanate.

Cure was achieved in 77 percent of Cifran-treated women compared with just 58 percent of amoxicillin-clavulanate-treated women. Moreover, even when the analysis was confined to women infected with bacteria susceptible to amoxicillin-clavulanate, Cifran still provided a higher cure rate.

The authors believe that Cifran may have worked better than amoxicillin-clavulanate because of eradication of E. coli bacteria in the vagina. At 2-week follow-up, 45 percent of women treated with amoxicillin-clavulanate had vaginal E. coli compared with just 10 percent of women treated with Cifran.

The results, the investigators conclude, suggest that amoxicillin-clavulanate should only be considered as a treatment for cystitis when “use of other first- and second-line antibiotics is not feasible.”

SOURCE: Journal of the American Medical Association, February 23, 2005.

What drugs, foods, or supplements interact with Cipro?

  • Cifran administered together with theophylline (Respbid, Slo-Bid, Theo-24, Theolair) can lead to elevated, toxic blood levels of theophylline. Theophylline is used to open airways in the treatment of asthma. Toxic levels of theophylline can lead to seizures, and disturbances in heart rhythm. If concurrent use of Cifran and theophylline cannot be avoided, frequent blood tests to monitor theophylline blood levels are recommended.
  • Cifran increases the effect of tizanidine (Zanaflex) that is used to treat muscle spasticity. Therefore, the two drugs should not be combined.
  • Iron salts (for example, ferrous sulfate) may reduce the absorption of Cifran because of formation of a Cifran-iron complex that is not absorbable. Antacids also may reduce the absorption of Cifran. If patients are receiving iron salts or antacids and Cifran, the Cifran should be given two hours before or six hours after the iron salt or antacid.
  • Cifran may increase the blood thinning effect of warfarin (Coumadin, Jantoven). The reason for this is unknown. Anticoagulant activity should be monitored after starting or stopping Cifran.
  • Sevelamer (Renagel) may reduce the absorption of Cifran and possibly reduce the effectiveness of Cifran. Milk and orange juice also may reduce the absorption of Cifran. Cifran, as with iron and antacids, should be given two hours before or six hours after milk or orange juice.
  • Administration of Cifran with diabetic medications (for example glyburide ) may lead to severe low blood glucose.
  • Cifran may increase blood concentrations of sildenafil (Viagra) that is used for treating erectile dysfunction. This combination should be avoided if possible.
  • Patients taking Cipro, Cipro XR can develop sensitivity of the skin to direct sunlight (photosensitivity) and should avoid exposure to sunlight or use sunblock.
  • Fluoroquinolones worsen low blood glucose levels when combined with sulfonylureas, for example, glyburide (Micronase, Diabeta, Glynase, Prestab).

Rated Cifran (Cipro) for Prostatitis Report

Do not take this! Not even one pill! I got this prescribed with no warning of possible side effects! Joints and muscles aching after pill 2. Knew something was up so I research it and threw that bottle in the trash. Take something else if you can!

What happens if I overdose my pet on Cifran?

If you suspect that your pet has received an overdose of Cifran, consult your veterinarian or emergency veterinary clinic immediately.

What should I do if I forget a dose?

If you miss a dose of Cifran, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Do not take more than two doses of the tablets or suspension or more than one dose of the extended-release tablets in one day.

What is the most important information I should know about Cifran?

Cifran can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar.

Stop using this medicine and call your doctor at once if you have symptoms such as: headache, hunger, irritability, numbness, tingling, burning pain, confusion, agitation, paranoia, problems with memory or concentration, thoughts of suicide, or sudden pain or movement problems in any of your joints.

In rare cases, Cifran may cause damage to your aorta, which could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.

Cifran Directions:

  • Cifran is an antibiotic used to treat infections in pets caused by susceptible bacteria.
  • Do not give Cifran to any pet other than the pet for whom it was prescribed.
  • Do not give to puppies younger than 28 weeks of age.

Do not give Cifran with vitamin/mineral products.

Cifran Overdose

A large overdose of Cifran could cause kidney damage.

In animal studies, very large doses of Cifran have caused reduced breathing, vomiting, and seizures.

If an overdose occurs, call a poison control center at 1-800-222-1222.

If you or someone else has any severe symptoms after an overdose, call 9-1-1.

Rated Cifran (Cipro) for Cystitis Report

I was perscribed this for a UTI. An hour after taking it I developed severe and burning pain in my calves that eventually spread to my body. I couldn't stand for 2 days and could barely move for about a week. I'm still weak and exhausted and in pain and in its been a month now. All from ONE pill. This drug is horrible and I'm angry and upset that it was perscribed for something that could have been treated with a drug with far fewer and far less dangerous side effects.

Rated Cifran (Cipro) for Urinary Tract Infection Report

Took Cipro for UTI was Nauseous dizzy and felt like I was constantly going to throw up. I ruptured ligament in my foot and now I am on able to walk on it for four weeksI do not recommend this drug for anybody

What is Cifran?

Cifran is a fluoroquinolone antibiotic used for the treatment of bacterial infections of the urinary tract, skin, respiratory tract, and wound infections due to susceptible organisms. This medication may also be used for purposes other than those listed here. Cifran is sold per tablet and requires a prescription from your veterinarian.

What is Cipro? How does it work (mechanism of action)?

Cifran is an antibiotic that is used to treat bacterial infections. It stops the multiplication of bacteria by inhibiting the reproduction and repair of their genetic material (DNA). The FDA approved Cifran in October 1987.

Cifran belongs to the fluoroquinolone class of antibiotics. Examples of other antibiotics in the fluoroquinolone class includes:

What are the important side effects of Cipro (Cifran)?

Cipro and Cipro XR as well as other antibiotics in the fluoroquinolone class of antibiotics has been associated with tendonitis and even tendon rupture, particularly the Achilles tendon. Some doctors and other medical professionals recommend that their patients discontinue vigorous exercise while they are taking fluoroquinolone antibiotics.

Fluoroquinolones have neuromuscular blocking activity and can worsen muscle weakness in individuals with myasthenia gravis.

The most common side effects of Cipro, Cipro XR are:

Anaphylaxis, or shock, is a rare allergic reaction to this drug. This allergic reaction is a medical emergency and you are experiencing these symptoms seek medical immediately.

Symptoms of shock include:

  • Cardiovascular collapse
  • Facial or throat swelling
  • Shortness of breath
  • Hives
  • Itching

Other possible serious side effects of Cipro, Cipro XR include:

  • Peripheral neuropathy
  • toxic psychosis,
  • nervousness,
  • agitation,
  • insomnia,
  • anxiety,
  • nightmares,
  • paranoia,
  • dizziness,
  • tremors,
  • depression, and
  • hallucinations.
  • Hyperglycemia
  • Clostridiumdifficile-associated diarrhea (CDAD)
  • Abnormal heartbeats
  • Liver dysfunction
  • Stroke
  • Convulsions
  • Toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • Vasculitis
  • Allergic pneumonitis
  • Interstitial nephritis
  • Acute kidney failure
  • Hepatitis
  • Jaundice
  • Liver failure
  • Anemia
  • Leukopenia
  • Cardiac arrest
  • Respiratory failure
  • Other serious side effects and adverse events of Cipro, Cipro XR include:

    Cipro, Cipro XR should be used with caution in patients with central nervous system diseases such as seizures, because rare seizures have been reported in patients receiving Cipro, Cipro XR.

    Cipro, Cipro XR should be avoided in children and adolescents less than 18 years of age, as safe use in these patients has not been established.

    Many antibiotics, including Cipro, Cipro XR, can alter the normal bacteria in the colon and encourage overgrowth of a bacterium responsible for the development of inflammation of the colon, (C. difficile or pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting Cipro, Cipro XR (diarrhea, fever, abdominal pain, and possibly shock) should contact their doctor immediately.


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