Cephoral tablets

Cephoral

  • Active Ingredient: Cefixime
  • 100 mg
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What is Cephoral?

The active ingredient of Cephoral brand is cefixime. Cefixime is a cephalosporin (SEF a low spor in) antibiotic. It works by fighting bacteria in your body.

Used for

Cephoral is used to treat diseases such as: Bladder Infection, Bronchitis, Gonococcal Infection, Disseminated, Gonococcal Infection, Uncomplicated, Kidney Infections, Otitis Media, Pneumonia, Sinusitis, STD Prophylaxis, Tonsillitis/Pharyngitis, Upper Respiratory Tract Infection, Urinary Tract Infection.

Side Effect

Possible side effects of Cephoral include: muscle aches; dizziness; paralysis; lower back or side pain; difficulty with swallowing; red, irritated eyes; swelling of the face, ankles, or hands; unusual tiredness or weakness.

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Summary

Cephoral (Suprax) is an antibiotic in the cephalosporin class of drugs. Cephoral (Suprax) is prescribed for the treatment of bacterial infections. Review side effects, drug interactions, warnings and precautions, and patient information prior to taking any medication.

How should this medicine be used?

Cephoral comes as a tablet, chewable tablet, capsule, and suspension (liquid) to take by mouth. It is usually taken with or without food every 12 or 24 hours . When used for the treatment of gonorrhea it may be given in a single dose. Take Cephoral at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Cephoral exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well before each use to mix the medication evenly.

If you are taking the chewable tablets, chew these tablets completely before swallowing; do not swallow the chewable tablets whole. If you have trouble chewing you may crush them before swallowing.

Cephoral tablets come with a line down the middle of the tablet. If your doctor tells you to take half a tablet, break it carefully on the line. Take half the tablet as directed, and save the other half for your next dose.

Different Cephoral products are absorbed by the body in different ways and cannot be substituted for one another. If you need to switch from one Cephoral product to another, your doctor may need to adjust your dose.

You should begin to feel better during the first few days of treatment with Cephoral. If your symptoms do not improve or get worse, call your doctor.

Continue to take Cephoral even if you feel better. If you stop taking Cephoral too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Pediatric Patients (6 Months Or Older)

The recommended dose is 8 mg/kg/day of the suspension. This may be administered as a single daily dose or may be given in two divided doses, as 4 mg/kg every 12 hours.

A suggested dose has been determined for each pediatric weight range. Refer to Table 1. Ensure all orders that specify a dose in milliliters include a concentration, because SUPRAX for oral suspension is available in three different concentrations (100 mg/5 mL, 200 mg/5 mL, and 500 mg/5 mL).

Table 1. Suggested doses for pediatric patients

Children weighing more than 45 kg or older than 12 years should be treated with the recommended adult dose. SUPRAX (Cephoral) chewable tablets must be chewed or crushed before swallowing.

Otitis media should be treated with the chewable tablets or suspension. Clinical trials of otitis media were conducted with the chewable tablets or suspension, and the chewable tablets or suspension results in higher peak blood levels than the tablet when administered at the same dose.

Therefore, the tablet or capsule should not be substituted for the chewable tablets or suspension in the treatment of otitis media .

In the treatment of infections due to Streptococcus pyogenes, a therapeutic dosage of Cephoral should be administered for at least 10 days.

Cephoral is a broad-spectrum antibiotic, which means that it is active against a wide variety of bacteria. It is used to treat short-term (acute) bacterial infections such as urinary tract infections, chest and throat infections, and ear infections. Cephoral treats an infection by killing the bacteria that are causing it.

2 Uses and Applications

Cefdinir is a third-generation oral cephalosporin antibiotic similar to Cephoral . It is reported to be much more active in vitro than Cephoral against Staphylococcus aureus and Enterococcus faecalis, but it is less active against Enterobacteriaceae. It is given by mouth in a usual dose of 600 mg daily as a single dose or in two divided doses. Children may be given 14 mg/kg body-weight daily up to a maximum of 600 mg. Doses should be reduced in patients with renal impairment (with a creatinine clearance of less than 30 mL/min) to 300 mg once daily .

Dosage Forms And Strengths

SUPRAX is available for oral administration in the following dosage forms and strengths:

  • Film-coated tablets provide 400 mg of Cephoral as trihydrate. These are white to off-white, film-coated, capsule shaped tablets with beveled edges and a divided score line on each side. The tablet is debossed with “SUPRAX” across one side and “LUPIN” across the other side.
  • Capsules provide 400 mg of Cephoral as trihydrate. These are size “00EL” capsules with pink opaque cap and pink opaque body with “LU” on the cap and “U43” on the body in black ink. Capsules contain white to yellowish white granular powder.
  • Chewable tablets provide either 100 mg or 150 mg or 200 mg of Cephoral as trihydrate. The 100 mg tablet is pink, round tablet, debossed with “SUPRAX 100” on one side and “LUPIN” on other side. The 150 mg tablet is pink, round tablet, debossed with “SUPRAX 150” on one side and “LUPIN” on other side. The 200 mg tablet is pink, round tablet, debossed with “SUPRAX 200” on one side and “LUPIN” on other side.
  • Powder for oral suspension, when reconstituted, provides either 100 mg/5 mL or 200 mg/5 mL or 500 mg/5 mL of Cephoral as trihydrate. For 100 mg/5 mL and 200 mg/5 mL, the powder has an off white to pale yellow color and is strawberry flavored. For 500 mg/5 mL, the powder has an off white to cream color and is strawberry flavored.

What is Cephoral, and how does it work (mechanism of action)?

Cephoral is a semi-synthetic (partially man-made), oral antibiotic in the cephalosporin family of antibiotics. The cephalosporin family includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefprozil (Cefzil), and many injectable forms. Like other cephalosporins, Cephoral stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together; most bacteria cannot survive without a cell wall. Cephoral is active against a very wide spectrum of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes (the cause of strep throat), Hemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella, Proteus mirabilis, Salmonella, Shigella, and Neisseria gonorrhoeae. The FDA approved Cephoral in April 1989.


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