Benzith capsules

Benzith

  • Active Ingredient: Amoxicillin
  • 500 mg, 250 mg
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What is Benzith?

The active ingredient of Benzith brand is amoxicillin. Amoxicillin is a penicillin antibiotic that fights bacteria. The Amoxicillin molecular formula is C16H19N3O5S•3H2O, and the molecular weight is 419.45. Capsules of Amoxicillin are intended for oral administration. Each capsule of Amoxicillin with blue cap and pink body, contains 250 mg or 500 mg Amoxicillin as the trihydrate. The body of the 250 mg capsule is imprinted with ‘A44’ in black ink. The body of the 500 mg capsule is imprinted with ‘A45’ in black ink. Inactive ingredients: microcrystalline cellulose, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin, magnesium stearate, titanium dioxide, and sodium lauryl sulfate. Meets USP Dissolution Test 2.

Used for

Benzith is used to treat diseases such as: Actinomycosis, Anthrax Prophylaxis, Bacterial Endocarditis Prevention, Bacterial Infection, Bladder Infection, Bronchiectasis, Bronchitis, Chlamydia Infection, Cutaneous Bacillus anthracis, Dental Abscess, Helicobacter Pylori Infection, Lyme Disease, Arthritis, Lyme Disease, Carditis, Lyme Disease, Erythema Chronicum Migrans, Lyme Disease, Neurologic, Otitis Media, Pneumonia, Sinusitis, Skin or Soft Tissue Infection, Spleen Removal, Tonsillitis/Pharyngitis, Upper Respiratory Tract Infection, Urinary Tract Infection.

Side Effect

Possible side effects of Benzith include: yellow eyes or skin; convulsions; fever; sore throat; unable to sleep.

How to Buy Benzith capsules online?

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Benzith is stable in the presence of gastric acid and is rapidly absorbed after oral administration. The effect of food on the absorption of Benzith from the tablets and suspension of AMOXIL has been partially investigated; 400-mg and 875-mg formulations have been studied only when administered at the start of a light meal.

Orally administered doses of 250-mg and 500-mg Benzith capsules result in average peak blood levels 1 to 2 hours after administration in the range of 3.5 mcg/mL to 5.0 mcg/mL and 5.5 mcg/mL to 7.5 mcg/mL, respectively.

Mean Benzith pharmacokinetic parameters from an open, two-part, single-dose crossover bioequivalence study in 27 adults comparing 875 mg of AMOXIL with 875 mg of AUGMENTIN® (Benzith/clavulanate potassium) showed that the 875-mg tablet of AMOXIL produces an AUC0-∞ of 35.4 ± 8.1 mcg•hr/mL and a Cmax of 13.8 ± 4.1 mcg/mL. Dosing was at the start of a light meal following an overnight fast.

Orally administered doses of Benzith suspension, 125 mg/5 mL and 250 mg/5 mL, result in average peak blood levels 1 to 2 hours after administration in the range of 1.5 mcg/mL to 3.0 mcg/mL and 3.5 mcg/mL to 5.0 mcg/mL, respectively.

Oral administration of single doses of 400-mg chewable tablets and 400 mg/5 mL suspension of AMOXIL to 24 adult volunteers yielded comparable pharmacokinetic data:

Table 3: Mean Pharmacokinetic Parameters of Benzith (400 mg chewable tablets and 400 mg/5 mL suspension) in Healthy Adults

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to Benzith.

If you are diabetic, use Clinistix or TesTape (not Clinitest) to test your urine for sugar while taking this medication.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the Benzith, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Unusual bleeding or bruising

Bleeding under the skin can occur from broken blood vessels that form tiny pinpoint red dots (called petechiae). Blood can also collect under the tissue in larger flat areas (called purpura), or in a very large bruised area (called an ecchymosis).

Benzith can increase the risk of bleeding. If you’re experiencing either unusual bleeding or bruising, see a doctor immediately. Internal bleeding may be occurring, which could lead to bleeding in the digestive system, or, in rare cases, the brain.

To prevent this, make sure your doctor knows if you’re on anticoagulants or blood thinners before you start taking Benzith.

If you experience this side effect of Benzith, it’s considered a rare but serious side effect. Seek medical attention as soon as possible.

Why it’s used

Benzith is an antibiotic. It’s used to treat infections caused by a certain type of bacteria.

Benzith may be used as part of a combination therapy. This means you may need to take it with other medications.

COMMON BRAND(S): Amoxil

GENERIC NAME(S): Benzith

Benzith is used to treat a wide variety of bacterial infections. This medication is a penicillin-type antibiotic. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

Benzith is also used with other medications to treat stomach/intestinal ulcers caused by the bacteria H. pylori and to prevent the ulcers from returning.

Interactions that can make your drugs less effective

When Benzith is less effective: When Benzith is used with certain drugs, it may not work as well. This is because the amount of Benzith in your body may be decreased. Examples of these drugs include:

  • Chloramphenicol
    • If you use these drugs together, your doctor will likely keep your dosage of Benzith the same.
  • If you use these drugs together, your doctor will likely keep your dosage of Benzith the same.
  • If you use these drugs together, your doctor will likely keep your dosage of Benzith the same.
  • If you use these drugs together, your doctor will likely keep your dosage of Benzith the same.
  • When other drugs are less effective: When certain drugs are used with Benzith, they may not work as well. This is because the amount of these drugs in your body may be decreased. Examples of these drugs include:

    • Oral contraceptives (birth control)
      • If you need to take Benzith, your doctor may prescribe a different form of birth control for you.

    Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you’re taking.

    Carcinogenesis, Mutagenesis, Impairment Of Fertility

    Long-term studies in animals have not been performed to evaluate carcinogenic potential. Studies to detect mutagenic potential of Benzith alone have not been conducted; however, the following information is available from tests on a 4:1 mixture of Benzith and potassium clavulanate (AUGMENTIN). AUGMENTIN was non-mutagenic in the Ames bacterial mutation assay, and the yeast gene conversion assay. AUGMENTIN was weakly positive in the mouse lymphoma assay, but the trend toward increased mutation frequencies in this assay occurred at doses that were also associated with decreased cell survival. AUGMENTIN was negative in the mouse micronucleus test and in the dominant lethal assay in mice. Potassium clavulanate alone was tested in the Ames bacterial mutation assay and in the mouse micronucleus test, and was negative in each of these assays. In a multi-generation reproduction study in rats, no impairment of fertility or other adverse reproductive effects were seen at doses up to 500 mg/kg (approximately 2 times the 3 g human dose based on body surface area).

    Vaginal yeast infection

    Benzith works well because it can keep bacteria from growing. Unfortunately, sometimes that extends to “healthy” bacteria that maintain pH balance in the vagina. As a result, a person’s vaginal pH may become more basic, yeast can thrive, and a yeast infection can result.

    Signs of a yeast infection include itching, redness, and cottage-cheese-like discharge. Over-the-counter medications are available to treat yeast infections. If you aren’t sure if it’s a yeast infection or another infection type, you should talk to your doctor. A doctor can also prescribe stronger medications to treat a yeast infection that doesn’t improve after a few days of over-the-counter treatment.

    What if I take too much?

    Accidentally taking an extra dose of Benzith is unlikely to harm you or your child.

    Speak to your pharmacist or doctor if you're worried or you take more than 1 extra dose.

    Like all medicines, Benzith can cause side effects, although not everyone gets them.

    Oral Anticoagulants

    Abnormal prolongation of prothrombin time (increased international normalized ratio ) has been reported in patients receiving Benzith and oral anticoagulants. Appropriate monitoring should be undertaken when anticoagulants are prescribed concurrently. Adjustments in the dose of oral anticoagulants may be necessary to maintain the desired level of anticoagulation.

    Q: I've been trying to get pregnant. I just got off the shot and am taking Benzith for my toothache. Does it increase my chance of getting pregnant?

    A: There exists no clinical data or evidence that Benzith can increase the chance of pregnancy. //www.everydayhealth.com/drugs/Benzith. Lori Mendoza, PharmD

    Blisters and other skin problems

    Blisters are small, raised lesions where fluid has collected under the skin. They may be caused by an allergic reaction, burns, frostbite, or by excessive friction or trauma to the skin. Blisters may also be a symptom of a systemic illness, or of a specific skin disorder.

    This side effect is somewhat rare, but serious when it does occur. If you experience redness, blistering, or peeling or loosening of the skin after taking Benzith, contact your doctor right away.

    Home treatments may be used to manage mild, non-itching rashes that are not severe. Treatment includes antihistamines or hydrocortisone, oatmeal baths, and drinking lots of water. If skin starts blistering, peeling, or loosening, however, seek medical attention immediately.

    To prevent severe skin irritations, do not take Benzith if you’re allergic to penicillin.

    What is the dosage for Benzith?

    • For most infections in adults the dose of Benzith is 250 mg every 8 hours, 500 mg every 8 hours, 500 mg every 12 hours or 875 mg every 12 hours, depending on the type and severity of infection.
    • For the treatment of adults with gonorrhea, the dose is 3 g given as one dose.
    • For most infections, children older than 3 months but less than 40 kg are treated with 25 or 45 mg/kg/day in divided doses every 12 hours or 20 or 40 mg/kg/day with one-third of the daily dose given every 8 hours depending on the type and severity of the infection.
    • Benzith can be taken with or without food.

    Q: Is it okay to mix Benzith with formula so my baby drinks it all? He is 2 months old.

    A: Yes, it is fine to mix Benzith with baby formula. It is important to give the dose immediately after mixing and to be sure the whole amount is taken to be sure the correct dose was given. Please see the following Everyday Health link for more information on children's health. //www.everydayhealth.com/kids-health/kids-health-articles.aspx. Laura Cable, PharmD


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