The half-life of Augmaxcil is 61.3 minutes. Approximately 60% of an orally administered dose of Augmaxcil is excreted in the urine within 6 to 8 hours. Detectable serum levels are observed up to 8 hours after an orally administered dose of Augmaxcil. Since most of the Augmaxcil is excreted unchanged in the urine, its excretion can be delayed by concurrent administration of probenecid .
Do not use this medication if you are allergic to Augmaxcil or to any other penicillin antibiotic, such as ampicillin (Omnipen, Principen), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.
Before using Augmaxcil, tell your doctor if you are allergic to cephalosporins such as Omnicef, Cefzil, Ceftin, Keflex, and others. Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy.
Augmaxcil can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking this medicine. Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Augmaxcil will not treat a viral infection such as the common cold or flu. Do not share this medication with another person, even if they have the same symptoms you have.
Antibiotic medicines can cause diarrhea. This may happen while you are taking Augmaxcil, or within a few months after you stop taking it. This may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Augmaxcil and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
What happens if I miss giving a dose of Augmaxcil?
Give the missed dose as soon as you remember unless it is almost time for the next regularly scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.
What are the side effects of Augmaxcil?
Side effects due to Augmaxcil include
People who are allergic to the cephalosporin class of antibiotics, which are related to the penicillins, for example, cefaclor (Ceclor), cephalexin (Keflex), and cefprozil (Cefzil), may or may not be allergic to penicillins.
Serious but rare reactions include:
Augmaxcil can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting Augmaxcil (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.
Resistance to Augmaxcil is mediated primarily through enzymes called beta-lactamases that cleave the beta-lactam ring of Augmaxcil, rendering it inactive.
Augmaxcil has been shown to be active against most isolates of the bacteria listed below, both in vitro and in clinical infections as described in the INDICATIONS AND USAGE section.