Amoxifur capsules

Amoxifur

  • Active Ingredient: Amoxicillin
  • 500 mg, 250 mg
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What is Amoxifur?

The active ingredient of Amoxifur brand is amoxicillin. Amoxicillin is a penicillin antibiotic that fights bacteria. The Amoxicillin molecular formula is C16H19N3O5S•3H2O, and the molecular weight is 419.45. Capsules of Amoxicillin are intended for oral administration. Each capsule of Amoxicillin with blue cap and pink body, contains 250 mg or 500 mg Amoxicillin as the trihydrate. The body of the 250 mg capsule is imprinted with ‘A44’ in black ink. The body of the 500 mg capsule is imprinted with ‘A45’ in black ink. Inactive ingredients: microcrystalline cellulose, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin, magnesium stearate, titanium dioxide, and sodium lauryl sulfate. Meets USP Dissolution Test 2.

Used for

Amoxifur is used to treat diseases such as: Actinomycosis, Anthrax Prophylaxis, Bacterial Endocarditis Prevention, Bacterial Infection, Bladder Infection, Bronchiectasis, Bronchitis, Chlamydia Infection, Cutaneous Bacillus anthracis, Dental Abscess, Helicobacter Pylori Infection, Lyme Disease, Arthritis, Lyme Disease, Carditis, Lyme Disease, Erythema Chronicum Migrans, Lyme Disease, Neurologic, Otitis Media, Pneumonia, Sinusitis, Skin or Soft Tissue Infection, Spleen Removal, Tonsillitis/Pharyngitis, Upper Respiratory Tract Infection, Urinary Tract Infection.

Side Effect

Possible side effects of Amoxifur include: unable to sleep; pale skin; changes in behavior; puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue; sores, welting, or blisters; clay-colored stools.

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Side Effects

Diarrhea, nausea, or vomiting may occur. If any of these effects persist or worsen, tell the doctor or pharmacist promptly. Taking this medication with food will help to reduce stomach upset.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell the doctor right away if any of these rare but serious side effects occur: dark urine, persistent nausea/vomiting, severe stomach/abdominal pain, yellowing eyes/skin, easy bruising/bleeding, new signs of infection (such as fever, persistent sore throat), unusual tiredness.

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea or opioid medications if you have any of the following symptoms because these products may make them worse. Tell the doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact the doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Amoxifur can commonly cause a mild rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe allergic reaction. Therefore, get medical help right away if you develop any rash.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact the doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Amoxifur Overdose

Though rare, it's possible to take an overdose of Amoxifur.

If you or someone else takes too much medicine, call your local poison control center at 1-800-222-1222.

If the person collapses, stops breathing, or has any severe symptoms after an overdose, call 9-1-1.

How does Amoxifur work?

Amoxifur works by inhibiting the formation of bacterial cell walls.

Probenecid

Probenecid decreases the renal tubular secretion of Amoxifur. Concurrent use of Amoxifur and probenecid may result in increased and prolonged blood levels of Amoxifur.

What Is Amoxifur (Amoxil)?

Amoxifur is the generic form of the brand-name drug Amoxil, a drug used to treat bacterial infections.

Doctors prescribe Amoxifur to treat infections caused by bacteria that are sensitive to the drug, including E. coli, staphylococcus, streptococcus, H. influenzae, and H. pylori.

Your doctor may prescribe Amoxifur to treat infections of the skin, throat, ears, nose, stomach, lungs, and urinary tract infections (UTI).

However, the drug will not work against infections caused by viruses such as cold and flu.

Also, guidelines urge doctors to prescribe Amoxifur only when an infection is strongly suspected to be caused by bacteria.

The Food and Drug Administration (FDA) first approved Amoxifur in the 1980s.

Today, different drug companies produce this antibiotic: Brand names include Amoxil and Moxatag.

Q: Is Amoxifur good for a painful boil?

A: Boils do not always require antibiotic therapy, often times they resolve on their own. To properly evaluate the boil and determine if treatment with an antibiotic is necessary, you should consult your health care provider. Amoxifur (Amoxil) is an antibiotic categorized as a penicillin which fights bacteria in your body. Amoxifur is indicated in the treatment of several different types of bacterial infections including ear infections, bladder infections, pneumonia, gonorrhea and E.coli or salmonella infections. Amoxifur is also approved to treat stomach ulcers caused by Helicobacter pylori (H. pylori) infections in combination with other medications, such as Biaxin (clarithromycin) and Prevacid (lansoprazole). Amoxifur is approved to treat some skin infections caused by certain bacteria. Some of the possible side effects associated with Amoxifur treatment include nausea, vomiting, stomach pain, vaginal itching or discharge, headache, swollen, black or hairy tongue or thrush (white patches inside the mouth and throat). Antibiotics, such as Amoxifur, can cause diarrhea. This could be a side effect of the medication or it could indicate a new infection. If you experience diarrhea that is watery, or has blood in it, contact your doctor immediately and do not take any medication to stop the diarrhea unless otherwise instructed. Amoxifur may be taken with or without food. If stomach upset occurs, take Amoxifur with food. Amoxifur should be taken for the entire length of time prescribed by your doctor. Although your symptoms may begin to resolve before the infection is completely treated, do not stop taking Amoxifur until you are finished with the course of therapy. Amoxifur will not treat a viral infection such as a cold or the flu. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Beth Isaac, PharmD

What other drugs will affect Amoxifur?

Before giving Amoxifur, tell your veterinarian if your pet is being given another antibiotic (for the same or a different infection), allopurinol, or probenecid. You may not be able to give Amoxifur or you may need to have the dosage adjusted. Drugs other than those listed here may also interact with Amoxifur. Talk to your veterinarian or pharmacist before giving any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Amoxifur side-effects

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with Amoxifur. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Allopurinol

The concurrent administration of allopurinol and Amoxifur increases the incidence of rashes in patients receiving both drugs as compared to patients receiving Amoxifur alone. It is not known whether this potentiation of Amoxifur rashes is due to allopurinol or the hyperuricemia present in these patients.

Quality Control

Standardized susceptibility test procedures 2,3,4 require use of laboratory controls to monitor and ensure the accuracy and precision of the supplies and reagents used in the assay, and the techniques of the individuals performing the test control. Standard Amoxifur powder should provide the following range of MIC values provided in Table 5 4 . For the diffusion technique the criteria provided in Table 5 should be achieved.

Table 5: Acceptable Quality Control Ranges for Amoxifur a

Other uses for this medicine

Amoxifur also is sometimes used to treat Lyme disease, to prevent anthrax infection after exposure, and to treat anthrax infection of the skin . Talk with your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Amoxifur in vitro susceptibility testing methods for determining minimum inhibitory concentrations (MICs) and zone sizes have not been standardized, validated, or approved for testing H. pylori. Specimens for H. pylori and clarithromycin susceptibility test results should be obtained on isolates from patients who fail triple therapy. If clarithromycin resistance is found, a non-clarithromycin-containing regimen should be used.


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