Important: if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic. Do not take any more amoxidura and speak with your doctor or go to your local accident and emergency department straightaway.
If you experience any other symptoms which you think may be due to the antibiotic, speak with your doctor or pharmacist for further advice.
Pregnancy Category B. Reproduction studies have been performed in mice and rats at doses up to 2000 mg/kg (3 and 6 times the 3 g human dose, based on body surface area). There was no evidence of harm to the fetus due to amoxidura. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, amoxidura should be used during pregnancy only if clearly needed.
Dosing In Neonates And Infants Aged ≤ 12 Weeks ( ≤ 3 Months)
Treatment should be continued for a minimum of 48 to 72 hours beyond the time that the patient becomes asymptomatic or evidence of bacterial eradication has been obtained. It is recommended that there be at least 10 days' treatment for any infection caused by Streptococcus pyogenes to prevent the occurrence of acute rheumatic fever. Due to incompletely developed renal function affecting elimination of amoxidura in this age group, the recommended upper dose of AMOXIL is 30 mg/kg/day divided every 12 hours. There are currently no dosing recommendations for pediatric patients with impaired renal function.
How it works
amoxidura belongs to a class of drugs called penicillins. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
amoxidura works by killing bacteria and stopping its growth in your body.
amoxidura oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking.
To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with amoxidura are listed below.
3. Who can and can't take amoxidura
amoxidura can be taken by adults, including pregnant and breastfeeding women.
amoxidura can be taken by children.
Q: amoxidura suspension was left out of refrigerator for about 11 hours over night. Is is dangerous to give to our 8 year old? Has it gone bad?
A: According to Pharmacist's Letter, amoxidura suspension can be kept at room temperature for at least 10 days. Although refrigeration improves taste, it is not needed to maintain the potency or safety of the drug. For more health information, visit everydayhealth.com and sign up for free newsletters.
amoxidura diffuses readily into most body tissues and fluids, with the exception of brain and spinal fluid, except when meninges are inflamed. In blood serum, amoxidura is approximately 20% protein-bound. Following a 1-gram dose and utilizing a special skin window technique to determine levels of the antibiotic, it was noted that therapeutic levels were found in the interstitial fluid.
In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of amoxidura are not associated with significant clinical symptoms.
Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with amoxidura 1 .
Crystalluria, in some cases leading to renal failure, has also been reported after amoxidura overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of amoxidura crystalluria.
Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of amoxidura. amoxidura may be removed from circulation by hemodialysis.