Amoxi tablets

Amoxi

  • Active Ingredient: Amoxicillin
  • 500 mg, 250 mg
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What is Amoxi?

The active ingredient of Amoxi brand is amoxicillin. Amoxicillin is a penicillin antibiotic that fights bacteria. The Amoxicillin molecular formula is C16H19N3O5S•3H2O, and the molecular weight is 419.45. Capsules of Amoxicillin are intended for oral administration. Each capsule of Amoxicillin with blue cap and pink body, contains 250 mg or 500 mg Amoxicillin as the trihydrate. The body of the 250 mg capsule is imprinted with ‘A44’ in black ink. The body of the 500 mg capsule is imprinted with ‘A45’ in black ink. Inactive ingredients: microcrystalline cellulose, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin, magnesium stearate, titanium dioxide, and sodium lauryl sulfate. Meets USP Dissolution Test 2.

Used for

Amoxi is used to treat diseases such as: Actinomycosis, Anthrax Prophylaxis, Bacterial Endocarditis Prevention, Bacterial Infection, Bladder Infection, Bronchiectasis, Bronchitis, Chlamydia Infection, Cutaneous Bacillus anthracis, Dental Abscess, Helicobacter Pylori Infection, Lyme Disease, Arthritis, Lyme Disease, Carditis, Lyme Disease, Erythema Chronicum Migrans, Lyme Disease, Neurologic, Otitis Media, Pneumonia, Sinusitis, Skin or Soft Tissue Infection, Spleen Removal, Tonsillitis/Pharyngitis, Upper Respiratory Tract Infection, Urinary Tract Infection.

Side Effect

Possible side effects of Amoxi include: chest pain; diarrhea, watery and severe, which may also be bloody; cough; diarrhea; muscle aches; fever; red, irritated eyes.

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Why it’s used

Amoxi is an antibiotic. It’s used to treat infections caused by a certain type of bacteria.

Amoxi may be used as part of a combination therapy. This means you may need to take it with other medications.

What are the uses for Amoxi (what does it treat)?

  • Amoxi is used to treat infections due to bacteria that are susceptible to the effects of Amoxi.
  • middle ear,
  • tonsils,
  • throat,
  • larynx (laryngitis),
  • bronchi (bronchitis),
  • lungs (pneumonia),
  • genital and urinary tract,
  • Helicobacter pylori (H. pylori) infection
  • anthrax,
  • endocarditis,
  • urinary tract, and
  • skin.

Amoxi also is used to treat gonorrhea.

Q: How do antibiotics (specifically amoxycillin) affect glucose levels in a person with diabetes?

A: A review of the package insert and medical literature showed some reports of increased blood glucose levels in patients taking Amoxi or related antibiotics. These reports were rare and no scientific studies on this effect have been done. The package insert for Amoxi cautions users about the potential for an inaccurate result on urine glucose tests using CLINITEST, Benedict's Solution, or Fehling's Solution in patients taking Amoxi. It is recommended that glucose tests based on enzymatic glucose oxidase reactions (such as CLINISTIX) be used when patients are receiving Amoxi or similar antibiotics. For more information, please consult with your healthcare provider. Michelle McDermott, PharmD

Amoxi Overdose

Though rare, it's possible to take an overdose of Amoxi.

If you or someone else takes too much medicine, call your local poison control center at 1-800-222-1222.

If the person collapses, stops breathing, or has any severe symptoms after an overdose, call 9-1-1.

2. Key facts

  • For most infections, you'll start to feel better in a few days.
  • The most common side effects of Amoxi are feeling sick (nausea) and diarrhoea.
  • Liquid Amoxi can stain your teeth. This doesn't last and is removed by brushing.
  • You can drink alcohol while taking Amoxi.
  • Amoxi is also called by the brand name Amoxil.

Amoxi is stable in the presence of gastric acid and is rapidly absorbed after oral administration. The effect of food on the absorption of Amoxi from the tablets and suspension of AMOXIL has been partially investigated; 400-mg and 875-mg formulations have been studied only when administered at the start of a light meal.

Orally administered doses of 250-mg and 500-mg Amoxi capsules result in average peak blood levels 1 to 2 hours after administration in the range of 3.5 mcg/mL to 5.0 mcg/mL and 5.5 mcg/mL to 7.5 mcg/mL, respectively.

Mean Amoxi pharmacokinetic parameters from an open, two-part, single-dose crossover bioequivalence study in 27 adults comparing 875 mg of AMOXIL with 875 mg of AUGMENTIN® (Amoxi/clavulanate potassium) showed that the 875-mg tablet of AMOXIL produces an AUC0-∞ of 35.4 ± 8.1 mcg•hr/mL and a Cmax of 13.8 ± 4.1 mcg/mL. Dosing was at the start of a light meal following an overnight fast.

Orally administered doses of Amoxi suspension, 125 mg/5 mL and 250 mg/5 mL, result in average peak blood levels 1 to 2 hours after administration in the range of 1.5 mcg/mL to 3.0 mcg/mL and 3.5 mcg/mL to 5.0 mcg/mL, respectively.

Oral administration of single doses of 400-mg chewable tablets and 400 mg/5 mL suspension of AMOXIL to 24 adult volunteers yielded comparable pharmacokinetic data:

Table 3: Mean Pharmacokinetic Parameters of Amoxi (400 mg chewable tablets and 400 mg/5 mL suspension) in Healthy Adults

What should I avoid while taking Amoxi?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using Amoxi and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.


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