Doxycycline vs. Acnamino: What's the difference?
- Doxycycline and Acnamino are tetracycline antibiotics used to treat many different types of infections, including respiratory tract infections due to Hemophilus influenzae, Streptococcus pneumoniae, or Mycoplasma pneumoniae. Doxycycline and Acnamino are also used to treat Rocky Mountain spotted fever, typhus, and acne.
- Brand names for doxycycline include Vibramycin, Oracea, Adoxa, Atridox, Acticlate, Acticlate Cap, Doryx, Doxteric, Doxy, and Monodox.
- Brand names for Acnamino include Dynacin, Minocin, and Solodyn.
- Side effects of doxycycline and Acnamino that are similar include diarrhea or loose stools, nausea, vomiting, tooth discoloration, and photosensitivity (exaggerated sunburn).
- Side effects of doxycycline that are different from Acnamino include abdominal pain.
- Side effects of Acnamino that are different from doxycycline include headache, fatigue, dizziness, itching, and reduced bone development in children.
Rated Acnamino for Acne Report
I started taking this drug around September or October of 2017 and was set to be weaned off of it in December of 2017. In terms of treating my acne, it was effective while I took it but as soon as I started weaning off of it the acne came back. To that end, it was not very effective at treating my condition. From December 2017 until now, I have been in a low mental state. It has finally gotten better in recent months (currently February 2019), but after reading some of these reviews I am seriously considering if being taken off this drug induced depression in me. For the year after I went off the drug, I had severely decreased drive, almost-detrimental academic performance, and frequent suicidal thoughts. I'm not saying that there could not have been other factors, but the cessation of my Acnamino usage had impeccable timing with when I started feeling awful. While looking up Acnamino, I read that it had been discovered that Acnamino has properties which allow it to function as an antidepressant. I wonder if the drop from the emotional high that I was on for a few months left an impact. Take caution when using this drug.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to Acnamino.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking Acnamino.
Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the Acnamino, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
COMMON BRAND(S): Dynacin, Minocin
GENERIC NAME(S): Acnamino
Acnamino is used to treat a wide variety of infections. It may also be used along with other medications to treat severe acne. This medication belongs to a class of drugs known as tetracycline antibiotics. It works by stopping the growth of bacteria.
This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.
Rated Acnamino for Acne Report
VERY VERY irritated/itchy skin all over my body! Clears up acne good though!!
In summary, Acnamino has long been used as an antibiotic for acne vulgaris, perioral disease and cutaneous sarcoidosis, and it is currently used for the treatment of inflammatory diseases such as rheumatoid arthritis. However, Acnamino has now been demonstrated to have anti-inflammatory, immunomodulatory and neuroprotective effects. Various studies in animal models and some clinical trials have confirmed the beneficial effects and safety of Acnamino, alone or combined with other drugs, as a promising therapeutic for diseases with an inflammatory background. Multiple mechanisms of action have been proposed for Acnamino, which stands out as a drug affecting multiple targets. Its antioxidant properties, calcium chelation and ability to inhibit pro-inflammatory enzymes such as iNOS or MMPs may have prominent roles in its beneficial effects in most of the diseases considered in this review. However, other tetracyclines, especially doxycycline, have been reported to share some of these properties, yet have not exhibited a similar efficacy in the same models. Therefore, it seems that it is Acnamino's multiple targets that makes it such an outstanding drug among the tetracyclines. In addition, Acnamino has been shown to display several attractive advantages that deserve our attention: it is generally considered a safe drug in humans, with a known side-effect profile; it is relatively inexpensive, which makes it suitable for long-term use in these diseases; and, lastly, it is established as an oral therapy, being well absorbed (95–100%) and reaching most of the compartments of the body, including the CNS. Although a better understanding of the mechanisms involved in the action of Acnamino in vivo is required before its therapeutic potential can be accurately assessed, the encouraging results and attractive merits of this antibiotic indicate that it will have potential as a therapeutic approach for treating many of the diseases described in this review.
Side effects of Acnamino are:
- Tooth discoloration
- Reduced bone development in children
What is Acnamino?
Acnamino is a tetracycline antibiotic that fights bacteria in the body.
Acnamino is used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, chlamydia, tick fever, and others. It is also used for gonorrhoea, syphilis, and other infections as a second-line drug in those with a penicillin allergy.
Acnamino may also be used for purposes not listed in this medication guide.
Acnamino is a second-generation, semi-synthetic tetracycline that has been in therapeutic use for over 30 years because of its antibiotic properties against both gram-positive and gram-negative bacteria. It is mainly used in the treatment of acne vulgaris and some sexually transmitted diseases. Recently, it has been reported that tetracyclines can exert a variety of biological actions that are independent of their anti-microbial activity, including anti-inflammatory and anti-apoptotic activities, and inhibition of proteolysis, angiogenesis and tumour metastasis. These findings specifically concern to Acnamino as it has recently been found to have multiple non-antibiotic biological effects that are beneficial in experimental models of various diseases with an inflammatory basis, including dermatitis, periodontitis, atherosclerosis and autoimmune disorders such as rheumatoid arthritis and inflammatory bowel disease. Of note, Acnamino has also emerged as the most effective tetracycline derivative at providing neuroprotection. This effect has been confirmed in experimental models of ischaemia, traumatic brain injury and neuropathic pain, and of several neurodegenerative conditions including Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, Alzheimer's disease, multiple sclerosis and spinal cord injury. Moreover, other pre-clinical studies have shown its ability to inhibit malignant cell growth and activation and replication of human immunodeficiency virus, and to prevent bone resorption. Considering the above-mentioned findings, this review will cover the most important topics in the pharmacology of Acnamino to date, supporting its evaluation as a new therapeutic approach for many of the diseases described herein.
Rated Acnamino for Skin and Structure Infection Report
I was prescribed for perioral dermitis. One month, twice a day and once a day for two weeks after that. After two days of taking it, I had noticed my anxiety flare up and had a massive panic attack. Looked up reviews and bam. Never taking it again, nor do I recommend. I feel bad for the people that took so long to realize what was going on with their body. Always listen to your body no matter what!
Why is this medication prescribed?
Acnamino is used to treat infections caused by bacteria including pneumonia and other respiratory tract infections; certain infections of the skin, eye, lymphatic, intestinal, genital, and urinary systems; and certain other infections that are spread by ticks, lice, mites, and infected animals. It is also used along with other medications to treat acne. Acnamino is also used to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack). It can also be used in patients who cannot be treated with penicillin to treat certain types of food poisoning, and anthrax (a serious infection that may be spread on purpose as part of a bioterror attack). It can also be used to eliminate bacteria from your nose and throat that may cause meningitis (swelling of tissues around the brain) in others, even though you may not have an infection. Acnamino extended-release tablet (Solodyn) is only used to treat acne. Acnamino is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne.
Antibiotics such as Acnamino will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Effects of Acnamino on atherosclerosis
Various studies have proposed Acnamino to prevent atherosclerosis, in relation to its cytoprotective effects in vascular cells. Accordingly, Acnamino has been shown to protect against diabetic microvascular complications (Krady et al., 2005) and to reduce neointima formation in macrovascular disease following acute vascular injury of the rat carotid artery (Pinney et al., 2003). In these studies, a reduction in the number of vascular smooth muscle cells (VSMC) was seen after Acnamino treatment, which was attributed to an inhibition of MMP activity and cytokine-induced VSMC migration (Pinney et al., 2003; Yao et al., 2004). Moreover, Acnamino has been shown to inhibit VEGF-induced MMP-9 mRNA transcription and protein activation in human aortic VSMCs in vitro (Pinney et al., 2003; Yao et al., 2004). More recently, Shahzad et al. (2011) showed Acnamino to reduce plaque size and vascular stenosis in diet-induced atherosclerosis through a PARP-1 and p27Kip1-dependent mechanism. In vitro assays revealed that Acnamino reduced the proliferative process in different cell types, including human aortic smooth muscle cells (HASMC) and murine primary aortic VSMCs. These data may explain the lower number of VSMC observed within atherosclerotic plaques of ApoE-/- high-fat diet (HFD) mice treated with Acnamino (Shahzad et al., 2011). These authors also established that Acnamino's anti-proliferative effect in VSMC depended on p27Kip1, as it induced in vitro expression in both VSMCs and HASMCs, and in atherosclerotic plaques analysed ex vivo. Of note, the knockdown of p27Kip1 in primary mouse aortic cells abolished the anti-proliferative effect of Acnamino. In addition, Acnamino reduced poly(ADP-ribose) formation, a marker of PARP-1 activity, in plaques of the truncus brachiocephalicus of ApoE-/- HFD mice and markedly reduced PARP-1 expression, particularly in low-density lipoprotein-treated HASMCs. The reduction of atherosclerotic plaque size after Acnamino treatment, mainly due to its anti-proliferative effects on VSMCs, suggests a potential application of Acnamino on vascular complications. However, no clinical trials have been conducted yet.
Effects of Acnamino on inflammatory bowel disease
The effects of Acnamino on experimental colitis were first described in 2009 by Huang et al. (2009b), who reported its ability to prevent and treat dextran sodium sulphate-induced colitis, significantly diminishing the mortality rate and attenuating the severity of the disease. These beneficial effects were associated with reduced iNOS and MMP expression in the intestinal tissue. Supporting these observations, Garrido-Mesa et al. (2011a) confirmed the intestinal anti-inflammatory effect of Acnamino in experimental models of colitis in both mice and rats, showing it to have a higher efficacy than other antibiotics like metronidazole, traditionally used to treat human inflammatory bowel disease, although it was devoid of immunomodulatory properties (Perencevich and Burakoff, 2006). That study proposed that Acnamino's ability to modulate both the immune and the microbiological parameters of the disease contribute to its beneficial effects. Regarding the latter, these studies revealed that the imbalance in the composition of the intestinal microbiota that characterizes experimental colitis was restored after Acnamino treatment, while the other antibiotics tested did not show this effect. Furthermore, in a mouse model of reactivated colitis, the association of Acnamino with the probiotic Escherichia coli Nissle 1917, which has been reported to show beneficial effects in these intestinal conditions (Schultz, 2008), exerted a greater intestinal anti-inflammatory effect than the individual treatments and, in addition, was able to attenuate the reactivation of the colitis (Garrido-Mesa et al., 2011b). Therefore, combined immunomodulatory and anti-microbial properties of Acnamino could be very useful in the treatment of multifactorial conditions, like inflammatory bowel disease.
How does Acnamino work in acne?
Acnamino is used for the treatment of inflammatory acne. Acnamino is lipid soluble and is excreted in sebum. It decreases the production of free fatty acids in the sebum. These acids have an irritating effect on the skin and are produced by Propionibacterium acnes.
Several weeks are needed for significant decrease of the fatty acids and evident clinical effect. Acnamino decreases the activity of Propionibacterium acnes as well as its number.
What Is Acnamino and How Does It Work?
Acnamino is used to treat moderate to severe acne in people 12 years and older. It helps to reduce the number of pimples. Acnamino belongs to a class of drugs known as tetracycline antibiotics. It works by stopping the growth of bacteria that may make acne worse.
Acnamino treats acne that is thought to be caused by a bacterial infection. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.
Acnamino is also used to treat many different bacterial infections, such as urinary tract infections, severe acne, gonorrhea, tick fever, chlamydia, and others.
Acnamino is available under the following different brand names: Dynacin, Minocin, Minocin Kit, Solodyn, and Ximino.
What Are Side Effects Associated with Using Acnamino?
Common side effects of Acnamino include:
This is not a complete list of side effects and other serious side effects may occur. Call your doctor for information and medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Rated Acnamino for Acne Report
I had severe depression and suicide thoughts on this medication. It was awful