Virosil

Virosil

  • Active Ingredient: Acyclovir
  • 800 mg, 400 mg, 200 mg
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What is Virosil?

The active ingredient of Virosil brand is acyclovir. Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. Acyclovir will not cure herpes, but it can lessen the symptoms of the infection. The inhibitory activity of acyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV and VZV. This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue. The monophosphate is further converted into diphosphate by cellular guanylate kinase and into triphosphate by a number of cellular enzymes. In vitro, acyclovir triphosphate stops replication of herpes viral DNA. This is accomplished in 3 ways: 1) competitive inhibition of viral DNA polymerase, 2) incorporation into and termination of the growing viral DNA chain, and 3) inactivation of the viral DNA polymerase. The greater antiviral activity of acyclovir against HSV compared with VZV is due to its more efficient phosphorylation by the viral TK.

Used for

Virosil is used to treat diseases such as: Cold Sores, Herpes Simplex, Herpes Simplex - Congenital, Herpes Simplex Encephalitis, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Herpes Simplex, Mucocutaneous/Immunocompromised Host, Herpes Simplex, Suppression, Herpes Zoster, Infectious Mononucleosis, Mononucleosis, Ramsay Hunt Syndrome, Varicella-Zoster.

Side Effect

Possible side effects of Virosil include: Bleeding or oozing from puncture sites or mucous membranes (bowel, mouth, nose, or urinary bladder), continuing; itching or skin rash; pale skin; fast heartbeat; buccal mucosa tablet; nausea or vomiting; confusion.

How to Buy Virosil online?

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El Virosil puede provocar efectos secundarios. DГ­gale a su doctor si cualquiera de estos sГ­ntomas se vuelve severo o si no desaparece:

  • malestar estomacal
  • vГіmitos
  • diarrea
  • mareos
  • cansancio
  • agitaciГіn
  • dolor, especialmente en las articulaciones
  • pГ©rdida del cabello
  • cambios en la visiГіn

General

  • Take this drug at the time(s) recommended by your doctor.
  • You can take Virosil with or without food. Taking it with food may help reduce upset stomach.
  • Do not cut or crush this medication.
  • Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.

How it works

Virosil belongs to a class of drugs called antivirals. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Virosil works by lowering the ability of the herpes virus to multiply in your body. This treats the symptoms of your infection. However, this drug doesn't cure herpes infections. Herpes infections include cold sores, chickenpox, shingles, or genital herpes. Even with this drug, the herpes virus may still live in your body. Your symptoms may occur again later even after the symptoms of your current infection go away.

Virosil oral tablet doesn't cause drowsiness but it can cause other side effects.

How it works

Virosil belongs to a class of drugs called antivirals. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Virosil works by lowering the ability of the herpes virus to multiply in your body. This treats the symptoms of your infection. However, this drug doesn’t cure herpes infections. Herpes infections include cold sores, chickenpox, shingles, or genital herpes. Even with this drug, the herpes virus may still live in your body. Your symptoms may occur again later even after the symptoms of your current infection go away.

Virosil oral tablet doesn’t cause drowsiness but it can cause other side effects.

To use buccal Virosil, follow these steps:

  1. Find the area on the upper gum above your left and right incisor teeth (the teeth just to the left and right of your two front teeth).
  2. With dry hands, remove one delayed-release tablet from the container.
  3. Gently apply the tablet to the upper gum area as high as it will go on your gum above one of your incisor teeth on the side of your mouth with the cold sore. Do not apply it to the inside of the lip or cheek.
  4. Hold the tablet in place for 30 seconds.
  5. If the tablet does not stick to your gum or if it sticks to your cheek or the inside of your lip, reposition it to stick to your gum. Leave the tablet in place until it dissolves.
  6. Do not interfere with the placement of the tablet. Check to see if the tablet is still in place after eating, drinking, or rinsing your mouth.

If the delayed-release buccal tablet comes off within the first 6 hours of application, reapply the same tablet. If it still will not stick, then apply a new tablet. If you accidentally swallow the tablet within the first 6 hours of application, drink a glass of water and place a new tablet on your gum. If the tablet falls off or is swallowed 6 or more hours after application, do not apply a new tablet until your next regular time.

  • Take this drug at the time(s) recommended by your doctor.
  • You can take Virosil with or without food. Taking it with food may help reduce upset stomach.
  • Do not cut or crush this medication.
  • Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.

Other uses for this medicine

Virosil is also sometimes used to treat eczema herpeticum (a skin infection caused by the herpes virus) to treat and prevent herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV), and to treat oral hairy leukoplakia (condition that causes hairy white or gray-colored patches on the tongue or inside of the cheek).

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Virosil only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2019 Cerner Multum, Inc. Version: 5.08.

What should I avoid while taking Virosil?

Avoid brushing your teeth, chewing gum, or wearing an upper denture while you have a buccal tablet in your mouth. You may rinse your mouth gently. Drink plenty of liquids to prevent dry mouth.

Herpes infections are contagious and you can infect other people, even while you are being treated with Virosil. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

Taking this medicine will not prevent you from passing genital herpes to your sexual partner. Avoid sexual intercourse while you have active lesions or the first symptoms of an outbreak. Genital herpes may still be contagious through "viral shedding" from your skin, even if you have no symptoms.

Pediatric Use

Safety and effectiveness of oral formulations of Virosil in pediatric patients younger than 2 years of age have not been established.

Which drugs or supplements interact with Virosil?

Virosil may decrease levels of phenytoin (Dilantin) or valproic acid (Depakote, Depakote ER). Probenecid (Benemid) may increase Virosil serum levels by decreasing renal excretion of Virosil. Virosil may increase serum levels of theophylline (Theo-Dur, Respbid, Slo-Bid, Theo-24, Theolair, Uniphyl, Slo-Phyllin).

Combining Virosil with cidofovir (Vistide), amphotericin B (Fungizone) or other drugs that reduce kidney function may increase harmful effects on the kidney.

Q: What is Virosil?

A: Virosil (Zovirax) is an antiviral medication indicated for the acute treatment of herpes zoster (shingles), the treatment of initial episodes and the management of recurrent episodes of genital herpes and the treatment of chickenpox. Virosil is only approved, by the U.S. Food and Drug Administration (FDA), for the treatment of chickenpox in the pediatric population 2 year of age and older. The safety and effectiveness of oral Virosil in the pediatric population, younger than 2 years of age, has not been established. The dosage and administration of oral Virosil depends upon the indication for use and age of the patient. Virosil can be administered with or without food. Virosil is the generic equivalent of Zovirax and is currently available, for oral administration, in capsule and tablet form and as a suspension for patients who have difficulty swallowing pills. Treatment with Virosil should be initiated as soon as possible after the first appearance of symptoms, such as tingling, burning or blisters. Patients being treated with Virosil are advised to stay adequately hydrated and take each dose with a full glass of water to protect the kidneys. The most frequently reported adverse reactions differed among clinical trials of Virosil depending on the indication for use. During clinical trials of treatment with Virosil, the most frequently reported adverse reactions included nausea, vomiting, diarrhea, malaise and headache. For the treatment of shingles, there is no information regarding initiation of treatment more than 72 hours following the onset of rash. Patients should initiate treatment as soon as possible after diagnosis. For the treatment of chickenpox, information gathered during clinical studies reflects initiation of treatment within 24 hours following rash. There is no information available regarding the effectiveness of treatment initiated after 24 hours. Patients should be advised that Virosil is not a cure for genital herpes and there is no available research regarding whether Virosil will prevent the transmission of the virus to other individuals.

Adult Mice and Rats: The acute toxicity of oral Virosil was determined as shown in Table 6.

Table 6 : Acute Toxicity Studies

Warnings for certain groups

For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well. This may increase the levels of this drug in your body and cause more side effects.

This medication may also decrease your kidney function. This means your kidney disease may get worse. Your doctor will adjust your dose depending on how well your kidneys are working.

For pregnant women: Virosil is a category B pregnancy drug. That means two things:

  1. Studies of the drug in pregnant animals have not shown a risk to the fetus.
  2. There aren’t enough studies done in pregnant women to show if the drug poses a risk to the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should be used only if the potential benefit justifies the potential risk to the fetus.

Call your doctor right away if you become pregnant while taking this drug.

For women who are breastfeeding: Virosil may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your baby. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

For children: This drug hasn’t been studied in children younger than 2 years.

This dosage information is for Virosil oral tablet. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose


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