Vireth

Vireth

  • Active Ingredient: Acyclovir
  • 800 mg, 400 mg, 200 mg
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What is Vireth?

The active ingredient of Vireth brand is acyclovir. Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. Acyclovir will not cure herpes, but it can lessen the symptoms of the infection. The inhibitory activity of acyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV and VZV. This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue. The monophosphate is further converted into diphosphate by cellular guanylate kinase and into triphosphate by a number of cellular enzymes. In vitro, acyclovir triphosphate stops replication of herpes viral DNA. This is accomplished in 3 ways: 1) competitive inhibition of viral DNA polymerase, 2) incorporation into and termination of the growing viral DNA chain, and 3) inactivation of the viral DNA polymerase. The greater antiviral activity of acyclovir against HSV compared with VZV is due to its more efficient phosphorylation by the viral TK.

Used for

Vireth is used to treat diseases such as: Cold Sores, Herpes Simplex, Herpes Simplex - Congenital, Herpes Simplex Encephalitis, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Herpes Simplex, Mucocutaneous/Immunocompromised Host, Herpes Simplex, Suppression, Herpes Zoster, Infectious Mononucleosis, Mononucleosis, Ramsay Hunt Syndrome, Varicella-Zoster.

Side Effect

Possible side effects of Vireth include: hallucinations (seeing, hearing, or feeling things that are not there); blood in urine or stools; large hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs; decreased frequency of urination or amount of urine; itching or skin rash; Abdominal or stomach pain; changes in vision; sense of agitation or uneasiness.

How to Buy Vireth online?

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Before taking this medicine

You should not take this medicine if you are allergic to Vireth or valVireth (Valtrex). You should not take Vireth buccal tablets (Sitavig) if you are allergic to milk proteins.

To make sure Vireth is safe for you, tell your doctor if you have:

kidney disease; or

a weak immune system (caused by disease or by using certain medicine).

Vireth is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection.

Vireth passes into breast milk, but is considered compatible with breast feeding. Tell your doctor if you are breast-feeding a baby while taking this medication.

Use in younger children is not recommended due to potential risk of choking.

General

  • Take this drug at the time(s) recommended by your doctor.
  • You can take Vireth with or without food. Taking it with food may help reduce upset stomach.
  • Do not cut or crush this medication.
  • Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.

History and Etymology for Vireth

acycl(ic) + -o- + vir(us); from its containing less cyclic structure than its naturally occurring analogue guanosine

Important considerations for taking Vireth

Keep these considerations in mind if your doctor prescribes Vireth oral tablet for you.

Geriatric Use

Of 376 subjects who received ZOVIRAX (Vireth) in a clinical study of herpes zoster treatment in immunocompetent subjects ¡Ý50 years of age, 244 were 65 and over while 111 were 75 and over. No overall differences in effectiveness for time to cessation of new lesion formation or time to healing were reported between geriatric subjects and younger adult subjects. The duration of pain after healing was longer in patients 65 and over. Nausea, vomiting, and dizziness were reported more frequently in elderly subjects. Elderly patients are more likely to have reduced renal function and require dose reduction. Elderly patients are also more likely to have renal or CNS adverse events. With respect to CNS adverse events observed during clinical practice, somnolence, hallucinations, confusion, and coma were reported more frequently in elderly patients (see CLINICAL PHARMACOLOGY, ADVERSE REACTIONS: Observed During Clinical Practice, and DOSAGE AND ADMINISTRATION).


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