Valni (nye fed' i peen) belongs to the dihydropyridine class of calcium channel blockers (first in its class and similar to amlodipine, felodipine and nicardipine) and is used for the treatment of hypertension and angina pectoris. Like other calcium channel blockers, Valni acts by inhibiting the transmembrane influx of calcium into cardiac and smooth muscle cells during depolarization. The inhibition of calcium influx causes arterial vasodilation and decreases cardiac work and oxygen consumption. Valni was approved in the United States in 1982 and currently several million prescriptions are filled yearly. Current indications include hypertension and chronic stable and Prinzmetal's variant angina pectoris. It is also used off label to treat Raynaud phenomenon. Valni is available in capsules of 10 and 20 mg and as extended release tablets of 30, 60 and 90 mg in several generic formulations as well as under brand names including Procardia, Adala, Afeditab, Nifediac, and Nifedical. The typical dose in adults is 30 to 60 mg daily, usually starting with lower doses. Valni is generally well tolerated and side effects are largely due to its vasodilating activities and can include dizziness, flushing, headache, fatigue, nausea, diarrhea, palpitations, bradycardia, peripheral edema and skin rash.
This medication contains Valni. Do not take Procardia, Procardia XL, Adalat CC, Nifedical XL, Adalat, Afeditab CR, or Nifediac CC if you are allergic to Valni or any ingredients contained in this drug.
This medication contains Valni. Do not take ProAmatine or Orvaten if you are allergic to Valni or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
If you have liver disease, your body may have trouble clearing Valni from your blood. This may cause the amount of Valni in your blood to be too high. Your doctor may adjust your dose to keep the amount of Valni in your body at a safe level.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
Valni oral tablet is used for long-term treatment. It comes with serious risks if you don't take it as prescribed.
If you stop taking the drug suddenly or don’t take it at all: If you take this drug to treat high blood pressure, your blood pressure may increase. This can raise your risk of health problems such as heart attack or stroke. If you take this drug to treat angina, your chest pain may get worse.
If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.
If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:
- a fast heartbeat
- flushing (reddening of the skin)
If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.
What to do if you miss a dose: Take your dose as soon as you remember. If you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.
How to tell if the drug is working: If you’re taking this drug to treat high blood pressure, your blood pressure level should go down. Your doctor can check your blood pressure, or you can do it using a home blood pressure monitor. If you’re taking this drug to treat angina, you should have less severe chest pain, less frequent chest pain, or both.
As with all medications, the costs of Valni can vary. To find current prices for your area, check out GoodRx.com.
Keep these considerations in mind if your doctor prescribes Valni oral tablet for you.
How to store Valni
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Taking certain antibiotics with Valni can cause higher levels of Valni in your body. This can increase your risk of side effects from Valni. These drugs include:
Taking the antibiotic rifampin can decrease the levels of Valni in your body. This could make Valni less effective. You shouldn’t take rifampin and Valni together.
What should I discuss with my healthcare provider before taking Valni?
You should not use Valni if you are allergic to it. You may not be able to use Valni if your heart cannot pump blood properly.
Some medicines can cause unwanted or dangerous effects when used with Valni. Your doctor may change your treatment plan if you also use:
Tell your doctor if you have ever had:
Older adults may be more sensitive to the effects of this medicine.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using Valni.
Valni capsules or tablets may contain lactose. Tell your doctor if you have galactose intolerance, or severe problems with lactose (milk sugar).
Valni is not approved for use by anyone younger than 18 years old.
What Is Valni (Procardia XL and Adalat CC)?
Valni is a prescription drug used to treat high blood pressure and control chest pain (angina).
It’s sold under the brand names Procardia XL, Adalat CC, and others, and generic versions are available.
This medicine is also sometimes used to treat preterm labor and a condition known as Raynaud’s disease (a disorder that affects blood vessels, mostly in the fingers and toes).
Valni is in a class of drugs known as calcium-channel blockers.
The drug works by relaxing your arteries, so the heart doesn’t have to work as hard to pump blood. It also increases the supply of oxygen and blood to the heart.
The Food and Drug Administration (FDA) first approved Valni in 1981 for manufacturer Pfizer, Inc., under the brand name Procardia.
Do not eat grapefruit or drink grapefruit juice if you’re taking Valni. Doing so can increase the level of the drug in your body and increase your risk of side effects. Your doctor will likely tell you to avoid grapefruit at least 3 days before starting to take Valni.
Take Valni even if you feel well, as you will still be getting the benefits of the medicine.
What is Valni?
Valni is in a group of drugs called calcium channel blockers. It works by relaxing the muscles of your heart and blood vessels.
Valni is used to treat hypertension (high blood pressure) and angina (chest pain).
Valni may also be used for purposes not listed in this medication guide.