Cyclovax

Cyclovax

  • Active Ingredient: Acyclovir
  • 800 mg, 400 mg, 200 mg
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What is Cyclovax?

The active ingredient of Cyclovax brand is acyclovir. Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. Acyclovir will not cure herpes, but it can lessen the symptoms of the infection. The inhibitory activity of acyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV and VZV. This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue. The monophosphate is further converted into diphosphate by cellular guanylate kinase and into triphosphate by a number of cellular enzymes. In vitro, acyclovir triphosphate stops replication of herpes viral DNA. This is accomplished in 3 ways: 1) competitive inhibition of viral DNA polymerase, 2) incorporation into and termination of the growing viral DNA chain, and 3) inactivation of the viral DNA polymerase. The greater antiviral activity of acyclovir against HSV compared with VZV is due to its more efficient phosphorylation by the viral TK.

Used for

Cyclovax is used to treat diseases such as: Cold Sores, Herpes Simplex, Herpes Simplex - Congenital, Herpes Simplex Encephalitis, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Herpes Simplex, Mucocutaneous/Immunocompromised Host, Herpes Simplex, Suppression, Herpes Zoster, Infectious Mononucleosis, Mononucleosis, Ramsay Hunt Syndrome, Varicella-Zoster.

Side Effect

Possible side effects of Cyclovax include: Black, tarry stools; increased thirst; decreased frequency of urination or amount of urine; pinpoint red spots on skin; bluish coloring, especially of the hands and feet.

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Cyclovax Dosage

Your dose of Cyclovax will depend on why you're taking it.

Cyclovax comes in tablets, capsules, and liquid form. You can take it with or without food.

Lower doses may be best for elderly people and for anyone with kidney disease.

Common dosages are:

  • For treatment of shingles: 800 milligrams (mg) five times daily for 7 to 10 days
  • For genital herpes treatment: 200 mg five times daily for 10 days
  • For preventing a recurrence of genital herpes: 400 mg every 12 hours for 12 months
  • For treating chicken pox in adults and children who weigh more than 40 pounds: 800 mg four times daily for 5 days

How it works

Cyclovax belongs to a class of drugs called antivirals. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Cyclovax works by lowering the ability of the herpes virus to multiply in your body. This treats the symptoms of your infection. However, this drug doesn't cure herpes infections. Herpes infections include cold sores, chickenpox, shingles, or genital herpes. Even with this drug, the herpes virus may still live in your body. Your symptoms may occur again later even after the symptoms of your current infection go away.

Cyclovax oral tablet doesn't cause drowsiness but it can cause other side effects.

Cyclovax side effects

Get emergency medical help if you have any signs of an allergic reaction to Cyclovax: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

easy bruising or bleeding, purple or red pinpoint spots under your skin; or

signs of a kidney problem -little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath.

Common Cyclovax side effects may include:

general ill feeling;

mouth pain while using an Cyclovax buccal tablet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

WARNINGS

ZOVIRAX (Cyclovax) Capsules, Tablets, and Suspension are intended for oral ingestion only. Renal failure, in some cases resulting in death, has been observed with Cyclovax therapy (see ADVERSE REACTIONS: Observed During Clinical Practice and OVERDOSAGE). Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS), which has resulted in death, has occurred in immunocompromised patients receiving Cyclovax therapy.

Dosing Considerations

  • The dosage of ZOVIRAX® (Cyclovax) should be reduced in patients with impaired renal function.
  • Therapy should be initiated as soon as possible after a diagnosis of chickenpox or herpes zoster, or at the first sign or symptoms of an outbreak of genital herpes.
  • The recommended dose and duration of use is dependent on the indication.

Take as directed

Cyclovax oral tablet is used for short-term treatment of genital herpes, shingles, and chicken pox. It's used for long-term treatment of recurring genital herpes. This drug comes with serious risks if you don't take it as prescribed.

If you stop taking the drug suddenly or don't take it at all: The symptoms of your infection may not get better or may get worse.

If you miss doses or don't take the drug on schedule: Your medication may not work as well or may stop working completely. If you're taking this drug to prevent flare-ups of your infection, a certain amount needs to be in your body at all times. You shouldn't stop taking this drug without talking to your doctor first.

What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

If you take too much: You could have dangerous levels of the drug in your body and experience more severe side effects. If you think you've taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.

How to tell if the drug is working: The symptoms of your infection will get better.

Q: Can Cyclovax cause uncontrollable muscle twitching?

A: Cyclovax (Zovirax) //www.everydayhealth.com/drugs/Cyclovax is a medication used to treat viral infections. The most common side effects associated with the oral form of Cyclovax are diarrhea, nausea, vomiting, headache, and feeling tired (malaise). Cyclovax cream and ointment can cause skin irritation. A search of the prescribing information for Cyclovax did not specifically list uncontrollable muscle twitching as a side effect. Tell your health-care provider about any negative side effects from prescription drugs. You can also report them to the U.S. Food and Drug Administration by visiting www.fda.gov/medwatch or by calling 1-800-FDA-1088. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Lori Mendoza, PharmD

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to Cyclovax.

Do not let anyone else take or use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Q: What is Cyclovax used for?

A: Cyclovax (Zovirax) is an antiviral medication that can be used in the treatment of the herpes virus, including genital herpes, cold sores, and shingles. Cyclovax can also be used to help with the chicken pox virus. The most frequently reported adverse reactions differed among clinical trials of Cyclovax depending on the indication for use. During clinical trials of treatment with Cyclovax, the most frequently reported adverse reactions included nausea, vomiting, diarrhea, malaise and headache. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Kristen Dore, PharmD

By Chris Iliades, MD | Medically Reviewed by Niya Jones, MD, MPH

Latest Update: 2014-04-28 Copyright © 2014 Everyday Health Media, LLC

What is Cyclovax?

Cyclovax is an antiviral drug. It slows the growth and spread of the herpes virus in the body. It will not cure herpes, but it can lessen the symptoms of the infection.

Cyclovax is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chicken pox, as well as varicella (chickenpox), and cytomegalovirus.

Cyclovax may also be used for purposes not listed in this medication guide.

What are the side effects of Cyclovax?

The most common side effects are

Other reported side effects include:

What should I avoid while taking Cyclovax?

Avoid brushing your teeth, chewing gum, or wearing an upper denture while you have a buccal tablet in your mouth. You may rinse your mouth gently. Drink plenty of liquids to prevent dry mouth.

Herpes infections are contagious and you can infect other people, even while you are being treated with Cyclovax. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

Taking this medicine will not prevent you from passing genital herpes to your sexual partner. Avoid sexual intercourse while you have active lesions or the first symptoms of an outbreak. Genital herpes may still be contagious through "viral shedding" from your skin, even if you have no symptoms.


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