Nizale cream

Nizale

  • Active Ingredient: Ketoconazole
  • 200 mg
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What is Nizale?

The active ingredient of Nizale brand is ketoconazole. Ketoconazole is an antifungal medication that fights infections caused by fungus. Molecular Formula: C26H28Cl2N4O4 Molecular Weight: 531.43 After a single topical application to the chest, back and arms of normal volunteers, systemic absorption of ketoconazole was not detected at the 5 ng/mL level in blood over a 72-hour period. Two dermal irritancy studies, a human sensitization test, a phototoxicity study and a photoallergy study conducted in 38 male and 62 female volunteers showed no contact sensitization of the delayed hypersensitivity type, no irritation, no phototoxicity and no photoallergenic potential due to Ketoconazole Cream, 2%.

Used for

Nizale is used to treat diseases such as: Blastomycosis, Chromomycosis, Chronic Mucocutaneous Candidiasis, Coccidioidomycosis, Dermatophytosis, Esophageal Candidiasis, Histoplasmosis, Onychomycosis, Fingernail, Onychomycosis, Toenail, Oral Thrush, Paracoccidioidomycosis, Tinea Corporis, Tinea Versicolor, Vaginal Yeast Infection.

Side Effect

Possible side effects of Nizale include: dizziness; difficulty seeing at night; unusual bleeding or bruising; sore throat; chills; light-colored stools; blood in the urine or stools.

How to Buy Nizale tablets online?

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Nizale for Hair Loss: The Link Between the Two

After identifying its success in treating dandruff, scientists began looking into its ability to manage seborrheic dermatitis. They found that using a shampoo containing a 2% concentration for two to four weeks resulted in an 88% reduction in the condition. When the study’s participants continued to use it following the end of the trial period, their hair loss didn’t return.

It’s therefore fair to assume that Nizale is useful for treating seborrheic dermatitis. As this is a condition that involves temporary hair loss, using Nizale ability to break down the cell membrane of fungi will restore any temporary hair loss you encounter.

Interactions that increase your risk of side effects

Taking certain drugs with Nizale raises your risk of side effects.

  • Side effects from Nizale: Taking Nizale with certain medications raises your risk of side effects from Nizale. This is because the amount of Nizale in your body is increased. Examples of these drugs include:
    • ritonavir
    • atorvastatin
  • Pain drugs, such as buprenorphine, fentanyl, and oxycodone. Taking these drugs with Nizale may cause slowed breathing.
  • Anticoagulants, such as rivaroxaban, dabigatran, and warfarin. Taking these drugs with Nizale may increase your risk of bleeding.
  • Heart drugs, such as felodipine and nisoldipine. Taking these drugs with Nizale may cause swelling of your legs or arms and heart failure.
  • Tamsulosin. Taking these drugs together may cause headache, dizziness, and orthostatic hypotension (low blood pressure when you stand up from a sitting or lying position).
  • Digoxin. Taking these drugs together may cause dizziness, headache, and stomach pain. Your doctor may monitor your digoxin blood levels.
  • Eletriptan. Taking these drugs together may cause weakness, nausea, dizziness, and drowsiness.
  • Antipsychotic drugs, such as aripiprazole, buspirone, haloperidol, quetiapine, and risperidone. Taking these drugs with Nizale may cause dizziness, drowsiness, and headaches.
  • Ramelteon. Taking these drugs together may cause dizziness, drowsiness, and fatigue.
  • Antivirals such as indinavir, maraviroc, and saquinavir. Taking these drugs with Nizale may cause stomach pain, nausea, and headaches.
  • Blood pressure drugs, such as verapamil and aliskiren.Taking these drugs with Nizale may cause low blood pressure, low heart rate, and dizziness.
  • Drugs for erectile dysfunction, such as sildenafil, tadalafil, and vardenafil. Taking these drugs with Nizale may cause headaches, upset stomach, and muscle pain.
  • Drugs for urine problems, such as solifenacin and tolterodine. Taking these drugs with Nizale may cause dry mouth, headaches, and dizziness.

What is the dosage for Nizale?

Nizale may be taken with or without food. The oral dose range is 200-400 mg daily. Recurrent tinea versicolor is treated with 400 mg monthly. Topical formulations are administered to affected areas once or twice daily.

What should I discuss with my healthcare provider before using Nizale topical?

You should not use this medicine if you are allergic to Nizale.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

  • asthma or a sulfite allergy;
  • an allergic reaction to an antifungal medicine, such as clotrimazole, econazole, or miconazole.

Ask a doctor before using this medicine if you are pregnant.

You should not breast-feed while using Nizale topical.

Always follow directions on the medicine label about using this medicine on a child.

Drugs you should not use with Nizale

Certain drugs should not be taken with Nizale. Doing so can cause dangerous effects in the body. Examples of these drugs include:

  • Antiarrhythmic drugs, such as dofetilide, quinidine, and dronedarone. Taking these drugs with Nizale may cause a heart problem called QT prolongation. This is a change in the electrical activity in the heart. It can cause irregular heartbeats and be life-threatening.
  • Methadone. Taking these drugs together may cause a heart problem called QT prolongation. This is a change in the electrical activity in the heart. It can cause irregular heartbeats and be life-threatening.
  • Ranolazine. Taking these drugs together may cause a heart problem called QT prolongation. This is a change in the electrical activity in the heart. It can cause irregular heartbeats and be life-threatening.
  • Simvastatin or lovastatin. Taking Nizale with these drugs may cause muscle problems.
  • Triazolam, midazolam, or alprazolam. Taking these drugs together may make you feel very drowsy for a long period of time.
  • Eplerenone. Taking these drugs together may cause low blood pressure and low potassium levels.

How Do Shampoos that Contain Nizale Work?

Many people get a little confused when first researching Nizale and its uses for hair loss and how it fits in the treatment picture. Nizale comes in both pill and topical form. Commonly, Nizale tablets are used as an antifungal agent to treat a variety of skin infections although oral Nizale has no use in the treatment of hair loss.

Nizale in shampoos primary use is to eliminate scalp conditions such as dandruff. It does this by killing fungi and yeasts that grow on the scalp through interfering with their cell membranes. Nizale stops the fungi from producing ergosterol, which cell membranes need to survive. It is marketed as an antifungal pill for people with dandruff or a skin condition. However, this is not its only use. Nizale for hair loss is an effective way to treat scalp DHT.

To use the over-the-counter shampoo, follow these steps:

  1. Be sure that your scalp is not broken, cut, or irritated. Do not use Nizale shampoo if your scalp is broken or irritated.
  2. Wet your hair thoroughly.
  3. Apply the shampoo to your hair.
  4. Use your fingers to rub the shampoo until it forms a lather.
  5. Rinse all of the shampoo out of your hair with plenty of water.
  6. Repeat steps 2 to 5.

Interactions that can make your drugs less effective

  • When Nizale is less effective: When Nizale is used with certain drugs, it may not work as well to treat your condition. This is because the amount of Nizale in your body may be decreased. Examples of these drugs include:
    • Ranitidine, famotidine, cimetidine, pantoprazole, omeprazole, and rabeprazole. You should take Nizale with an acidic beverage, such as a non-diet soda, if you take these drugs together.
    • Aluminum hydroxide. You should take this drug 1 hour before or 2 hours after taking Nizale.
    • Antibiotics, such as isoniazid and rifabutin
    • Anticonvulsants, such as carbamazepine and phenytoin
    • Antivirals, such as efavirenz and nevirapine
    • Carbamazepine. Your doctor may monitor your carbamazepine levels.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

What is Nizoral? What is Nizale?

Nizoral is a shampoo designed to help the user treat dandruff, hair loss, and other scalp conditions such as seborrheic dermatitis. Nizoral for hair loss is very effective because it contains Nizale. The popular Nizoral A-D hampoo contains 1% Nizale which is sufficient for scalp treatment and the reduction of follicular inflammation that contributes to hair loss. The topical forumlas of Nizoral for hair loss have not been associated with any adverse effects. Nizoral also comes in tablet form and actually has the potential to cause liver damage over sustained long term use. It is prescription only and used for anti-fungus purposes. Oral Nizoral hasn’t been shown to have any benefits for hair loss.


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