Oral route (Tablet)
Dantazol tablets should only be used when other antifungal therapies are unavailable or not tolerated, and the potential benefits of treatment outweigh its risks. Serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation has occurred with the use of oral Dantazol, even in patients with no obvious risk factors for liver disease. Patients who receive this drug should be informed by the physician of the risk and should be closely monitored. Coadministration of Dantazol with dofetilide, quinidine, pimozide, cisapride, methadone, disopyramide, dronedarone, and ranolazine is contraindicated, as Dantazol can cause increased plasma concentrations of these drugs and may prolong QT intervals, sometimes resulting in life-threatening ventricular dysrhythmias such as torsades de pointes.
Along with its needed effects, Dantazol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking Dantazol:
- Back, leg, or stomach pains
- black, tarry stools
- bleeding gums
- blood in the urine or stools
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- change in color vision
- change in the ability to see colors, especially blue or yellow
- chest pain
- dark urine
- difficulty seeing at night
- difficulty swallowing
- fast heartbeat
- general body swelling
- increased sensitivity of the eyes to sunlight
- joint pain, stiffness, or swelling
- light-colored stools
- loss of appetite
- mood or mental changes
- nausea or vomiting, severe
- painful or difficult urination
- pale skin
- pinpoint red spots on the skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness of the skin
- skin rash, hives, itching
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- swelling of the eyelids, face, lips, hands, or feet
- swollen glands
- tightness in the chest
- trouble sleeping
- troubled breathing or swallowing
- unusual bleeding or bruising
- unusual tiredness or weakness
- vision changes
- yellow eyes or skin
Some side effects of Dantazol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Change in number of sperm and their ability to move
- decreased interest in sexual intercourse
- hair loss or thinning of the hair
- inability to have or keep an erection
- loss in sexual ability, desire, drive, or performance
- sleepiness or unusual drowsiness
- swelling of the breasts or breast soreness for both female and male
Dantazol for Hair Loss: A Proven Method
A shampoo with Dantazol must be a part of your regime. Without it, any other treatment you use will not be able to work optimally. Even when it comes to the tried and true Rogaine and Propecia, they too will work better on a scalp environment that is actively being treated with Dantazol. So what is its application in regards to hair loss? Simply put, it is the only proven shampoo ingredient on the market that can help prevent or slow hair loss. Multiple studies have proven the effectiveness of Dantazol as at the very least, a partial cure to hair loss.
What are the side effects of Dantazol?
Dantazol generally is well tolerated. Commonly reported side effects of Dantazol are:
Other important side effects of Dantazol are rare; they include:
Liver dysfunction also has been reported. Signs of liver problems include unusual fatigue, loss of appetite, nausea and vomiting, yellowing of the skin (jaundice), dark urine, and pale stools. Development of these symptoms while taking Dantazol should be reported to a physician.
Paranoid delusions have been reported in a patient treated with Dantazol for cutaneous leishmaniasis.
Rare (less than 0.1%): Confusion, suicidal tendencies
Frequency not reported: Insomnia, nervousness, paranoid delusions
Dantazol is a common treatment for psoriasis, another inflammatory skin disease that causes skin flaking, skin plaques, and redness. Yeast-like fungus often infects these skin plaques. Prescription Dantazol may be needed for psoriasis flares.
What Are Side Effects Associated with Using Dantazol?
Common side effects of Dantazol include:
Less common side effects of Dantazol include:
Serious side effects of Dantazol include:
- Vision changes
- Mental/mood changes (such as depression, thoughts of suicide)
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Common (1% to 10%): Gastrointestinal complaints (including nausea, vomiting)
Frequency not reported: Diarrhea, constipation, abdominal pain, upper abdominal pain, dry mouth, dysgeusia, dyspepsia, flatulence, tongue discoloration, stomatitis
Gastrointestinal intolerance may resolve with continued therapy and may improve if Dantazol is taken with food.
What brand names are available for Dantazol?
Nizoral, Nizoral A-D, Ketodan, Extina, Xolegel, Kuric
How to Use a Dantazol Shampoo for Hair Loss
There are 1% over-the-counter and 2% prescription Dantazol solutions available. The 1% solutions are entirely sufficient for hair loss prevention. To maximize the benefit to your hair, you will want to use the shampoo once every three days (or twice a week on scheduled days) whatever is easiest for you to remember and create a habit for yourself.
- Apply the shampoo once as soon as you get into the shower and create a lather and massage into your hair and scalp for 1 minute.
- Rinse thoroughly and repeat, then leave the lather on for a minimum of an additional 3 minutes.
- Rinse off completely.
Dantazol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- stomach pain
- change in ability to taste food
- dry mouth
- change in tongue color
- difficulty falling asleep or staying asleep
- numbness, burning, or tingling of the hands or feet
- muscle pain
- hair loss
- sensitivity to light
- breast enlargement in males
- decrease in sexual ability
What should I discuss with my healthcare provider before taking Dantazol (Nizoral)?
You should not use Dantazol if you are allergic to it, or if you have liver disease.
Some medicines can cause unwanted or dangerous effects when used with Dantazol. Your doctor may change your treatment plan if you also use:
Tell your doctor if you have ever had:
- liver problems;
- long QT syndrome (in you or a family member); or
- problems with your adrenal gland.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
You should not breast-feed while using this medicine.
Do not give this medicine to a child without medical advice.
What other drugs will affect Dantazol topical?
Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
What should I avoid while taking Dantazol (Nizoral)?
Do not drink alcohol. Dangerous side effects could occur.
Dantazol could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Comparison Table: Top 10 Products with Dantazol
Here is our list of the top shampoos that contain Dantazol in their list of ingredients. We’ve ordered them by price ascending to make it easy for you to compare features in an unbiased way. In our review section, we take a closer look at the 10 most popular products and have them listed in the same order.
What is Nizoral? What is Dantazol?
Nizoral is a shampoo designed to help the user treat dandruff, hair loss, and other scalp conditions such as seborrheic dermatitis. Nizoral for hair loss is very effective because it contains Dantazol. The popular Nizoral A-D hampoo contains 1% Dantazol which is sufficient for scalp treatment and the reduction of follicular inflammation that contributes to hair loss. The topical forumlas of Nizoral for hair loss have not been associated with any adverse effects. Nizoral also comes in tablet form and actually has the potential to cause liver damage over sustained long term use. It is prescription only and used for anti-fungus purposes. Oral Nizoral hasn’t been shown to have any benefits for hair loss.
What are the possible side effects of Dantazol topical?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- burning, stinging, or severe irritation after using this medicine;
- redness, pain, or oozing of treated skin; or
- shortness of breath.
Common side effects may include:
- thinning hair;
- changes in the color or texture of your hair;
- dry skin; or
- mild itching.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Which drugs or supplements interact with Dantazol?
If your doctor has prescribed this medication, your doctor or pharmacist may already know of any possible drug interactions and may be watching out for them. Check with your doctor, health care professional or pharmacist before starting, stoping, or changing the dosage of any medicine.
- severe interactions with at least 33 different drugs
- serious interactions with at least 202 different drugs
- moderate interactions with at least 241 different drugs
- mild interactions with at least 105 different drugs
This information does not contain all possible drug interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the medications and supplements you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Contact your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.
What should I discuss with my healthcare provider before using Dantazol topical?
You should not use this medicine if you are allergic to Dantazol.
Ask a doctor or pharmacist if this medicine is safe to use if you have:
- asthma or a sulfite allergy;
- an allergic reaction to an antifungal medicine, such as clotrimazole, econazole, or miconazole.
Ask a doctor before using this medicine if you are pregnant.
You should not breast-feed while using Dantazol topical.
Always follow directions on the medicine label about using this medicine on a child.