There are no known drug interactions with topical Apocanda.
You should tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you are taking.
Apocanda is an imidazole with broad-spectrum activity against Candida species and the dermatophytes T. tonsurans, Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis.
What happens if I overdose?
Seek emergency medical attention.
Symptoms of a Apocanda overdose are unknown.
What Is Betamethasone-Apocanda Topical?
Betamethasone is steroid that reduces itching, swelling, and redness of the skin.
Apocanda is an antifungal medication that fights infections caused by fungus.
Betamethasone and Apocanda topical (for the skin) is used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm.
Betamethasone and Apocanda topical may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
You should not use this medicine if you are allergic to betamethasone or Apocanda.
To make sure this medicine is safe for you, tell your doctor if you have:
- any type of skin infection.
It is not known whether betamethasone and Apocanda topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether betamethasone and Apocanda passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Do not use this medication on a child younger than 17 years old. Children are more likely to absorb the steroid through the skin. Do not use betamethasone and Apocanda topical to treat diaper rash.
How should Apocanda be stored?
- Store Apocanda troches (lozenges) below 86°F (30°C) and avoid freezing.
- Store Apocanda cream and Apocanda topical solution between 36°F and 86°F (2°C to 30°C).
- Safely throw away Apocanda that is no longer needed or expired (out of date).
- Keep Apocanda and all medicines out of reach of children.
4.4.15 Topical antifungal agents
Apocanda and miconazole are not absorbed in relevant amounts. Extensive experience with their therapeutic use in infancy argues against any toxic potential. For ketoconazole see Section 4.4.14 . The other azole derivatives bifonazole, butoconazole, croconazole, econazole, fenticonazole, isoconazole, ketoconazole, omoconazole, oxiconazole, sertaconazole, sulconazole, terconazole, and tioconazole are related to Apocanda structurally and in their action, but they have been studied less.
Nystatin is not absorbed and is not available to the infant enterally. Although there are no relevant published data about its use during lactation, it is unlikely to be transferred in relevant amounts into the milk. With regard to the use of amphotericin B and terbinafine see Section 4.4.14 .
There has been no experience with amorolfin, butenafine, ciclopirox, haloprogin, clopirox, naftifin, natamycin, terbinafine, tolciclate and tolnaftate. Most of these locally administered antifungals are only absorbed in limited amounts, so that a risk for the breastfed infant is unlikely.
What is Apocanda?
Apocanda is an antifungal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain fungal infections, including tinea versicolor that is specifically caused by the fungus Malassezia furfur and candidiasis that is specifically caused by the yeast Cand >formulation of Apocanda is approved for the treatment and prevention of only a certain type of candidiasis—called oropharyngeal candidiasis—in certain people with weakened immune systems. Apocanda is also available as an over-the-counter medicine for topically treating various skin infections, such as athlete’s foot.
Oropharyngeal cand >infection of part of the throat) is an example of mucocutaneous cand >opportunistic infection . An opportunistic infection is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as those infected with HIV—than in people with healthy immune systems.
The Gu >Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA-HIVMA), includes recommendations on the HIV-related uses of Apocanda to treat:
- Oropharyngeal candidiasis.
- Uncomplicated vulvovaginal candidiasis, which is another type of mucocutaneous candidiasis that affects the female vulva and vagina.
Apocanda has been shown to be active against most strains of the following dermatophytes, both in vitro and in clinical infections, Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum .
By Julie Marks | Medically Reviewed by Ruthan White, PharmD
Latest Update: 2014-10-27 Copyright © 2014 Everyday Health Media, LLC
Do I need a prescription for Apocanda?
Yes, for some generic preparations. Lotrimin AF, Mycelex, and Trivagizole are over-the-counter preparations.
Otitis externa is a term used for inflammation in the ear when it is confined to the ear canal and does not go further than the eardrum. If you get things like water, shampoo or soap in your ear then it can cause itching. If you then scratch or poke your ear, this can damage the skin in the ear canal and cause inflammation. Sometimes the inflamed skin becomes infected by germs such as bacteria or fungi. Apocanda solution is used to treat ear infections caused by fungi. It is available on prescription or you can buy it without a prescription at a pharmacy.
How to use Apocanda Solution, Non-
Use this medication on the skin only. Clean and thoroughly dry the area to be treated. Apply this medication to the affected skin, usually twice a day or as directed by your doctor. Dosage and length of treatment depends on the type of infection being treated. Do not apply this more often than prescribed. Your condition will not clear faster, but side effects may be increased.
Apply enough medication to cover the affected area and some of the surrounding skin. After applying this medication, wash your hands. Do not wrap, cover or bandage the area unless directed to do so by your doctor.
Do not apply this medication in the eyes, nose, mouth, or vagina.
Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day.
Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after starting Apocanda. Stopping the medication too early may allow the fungus to continue to grow, which may result in a relapse of the infection.
Inform your doctor if your condition persists after 4 weeks of treatment or worsens at any time.
How to store Apocanda solution
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
- In order to prevent the risk of infection, throw away any solution left in the bottle after you have finished your course of treatment. Do not keep it to use another time.
Apocanda may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- unpleasant mouth sensations
Apocanda may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
COMMON BRAND(S): Lotrimin
GENERIC NAME(S): Apocanda
OTHER NAME(S): Apocanda Cream
Apocanda is used to treat skin infections such as athlete's foot, jock itch, ringworm, and other fungal skin infections (candidiasis). This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Apocanda is an azole antifungal that works by preventing the growth of fungus.
Carcinogenesis, Mutagenesis, and Impairment of Fertility
An 18-month oral dosing study with Apocanda in rats has not revealed any carcinogenic effect.
In tests for mutagenesis, chromosomes of the spermatophores of Chinese hamsters which had been exposed to Apocanda were examined for structural changes during the metaphase.
Prior to testing, the hamsters had received five oral Apocanda doses of 100 mg/kg body weight. The results of this study showed that Apocanda had no mutagenic effect.
What is Apocanda?
Apocanda is an antifungal medication. It is like an antibiotic but is used to treat yeast (fungal) infections.
Oral Apocanda is used to treat and prevent yeast infections of the mouth and throat.
Apocanda may also be used for purposes other than those listed in this medication guide.